Real Time Single Cell Analysis of Bid Cleavage and Bid ...
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Real Time Single Cell Analysis ...
Bcl-2 homology domain (BH) 3-only proteins couple stress signals to evolutionarily conserved mitochondrial apoptotic pathways. Caspase 8-mediated cl ...
650.70 KB
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Phenotype Data: A Neglected Res ...
To a great extent, our phenotype is determined by our genetic material. Many genotypic modifications may ultimately become manifest in more or less p ...
392.38 KB
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The Role of the COG Database in ...
A major breakthrough in classifying proteins from different microbial genomes in terms of sequence similarity was the development of the COG concept ...
152.48 KB
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OX40:OX40L Axis: Emerging Targe ...
Recent advances in our understanding of the mechanisms through which T cells are activated have led to new therapeutic approaches in the treatment of ...
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152.63 KB
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Accessibility Control of Recomb ...
During B cell development, two somatic DNA recombination events occur at the immunoglobulin heavy chain loci: VDJ recombination and class switch reco ...
503.30 KB
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The Role of the COG Database in ...
A major breakthrough in classifying proteins from different microbial genomes in terms of sequence similarity was the development of the COG concept ...
152.48 KB
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De Novo and Molecular Target-In ...
There is immediate potential to enhance success and innovation in drug development by pairing newly emerging approaches in medicinal chemistry and co ...
217.43 KB
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Liposomal Muramyl Tripeptide Ph ...
About one third of osteosarcoma patients develop lung metastasis refractory to chemotherapy. Recent studies indicate that biological response modifie ...
220.63 KB
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Cholinergic Treatment of Trauma ...
In spite of affecting the life of millions of people, chronic traumatic brain injury (TBI) has not been hitherto treatable with effective pharmacolog ...
224.09 KB
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Phenotype Data: A Neglected Res ...
To a great extent, our phenotype is determined by our genetic material. Many genotypic modifications may ultimately become manifest in more or less p ...
392.38 KB
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Colloidal and Pharmacological A ...
Human albumin is extensively used and investigated in clinical fluid management. Whether albumin confers sufficient benefit to justify its cost has b ...
485.63 KB
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Induction of RhoGAP and Patholo ...
Novel experiments with Ultrasound Associated with High Frequency Electromagnetic Field (UAHFEMF) irradiation on rats and mice found evidences of char ...
504.60 KB
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GSK3 at the Edge: Regulation of ...
GSK3 is a multifunctional protein kinase that is pivotal for the regulation of metabolism, the cytoskeleton, and gene expression. Multicellular eukar ...
513.75 KB
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Ribonucleotide Reductase Inhibi ...
Ribonucleotide reductase (RR) is a multisubunit enzyme responsible for the reduction of ribonucleotides to their corresponding deoxyribonucleotides, ...
524.30 KB
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Bacterial Stationary-State Muta ...
Mechanisms of cellular adaptation may have some commonalities across different organisms. Revealing these common mechanisms may provide insight in th ...
453.55 KB
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Crystal structure of SV40 large ...
The transformation potential of Simian Virus 40 depends on the activities of large T-antigen (LTag), which interacts with several cellular tumor supp ...
841.49 KB
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Phenotype Data: A Neglected Res ...
To a great extent, our phenotype is determined by our genetic material. Many genotypic modifications may ultimately become manifest in more or less p ...
392.38 KB
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Estrogen Signaling Multiple Pat ...
Steroid hormones exert profound effects on cell growth, development, differentiation, and homeostasis. Their effects are mediated through specific in ...
295.71 KB
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A rapid and specific PCR–ELISA ...
Background: Salmonella continues to be a major food borne pathogen for animals and humans. A sensitive and specific PCR–ELISA technique was developed ...
161.91 KB
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Gain-of-Function Mutations of R ...
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors in human gastrointestinal tract. We first found that most GISTs expres ...
253.93 KB
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Bcl2’s Flexible Loop Domain Reg ...
p53 not only functions as a transcription factor but also has a direct, apoptogenic role at the mitochondria. We have discovered that DNA damage-indu ...
965.77 KB
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The Role of the COG Database in ...
A major breakthrough in classifying proteins from different microbial genomes in terms of sequence similarity was the development of the COG concept ...
152.48 KB
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Multiple Functions of Rad9 for ...
DNA-damage checkpoints sense and respond to genomic damage. Human Rad9 (hRad9), an evolutionarily conserved gene with multiple functions for preservi ...
145.86 KB
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DNA Polymerase ŋ , the Product ...
DNA polymerase (PolH) is the product of the xeroderma pigmentosum variant (XPV) gene and a well-characterized Y-family DNA polymerase for translesi ...
971.46 KB
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A theoretical and experimental ...
The behavior of membrane bioreactors operating in recycle configuration is characterized from both a theoretical and an experimental point of view. T ...
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