Standard of Practice for the In ...
Isolated iliac artery aneurysms are uncommon, comprising less than 2% of all abdominal aneurysmal disease. Although they have a fairly innocuous nat ...
Paediatric Interventional Urora ...
Paediatric interventional uroradiology lies at the intersection of the disciplines of paediatric interventional radiology and paediatric endourology ...
Tumor immune surveillance and o ...
the past few years, cancer immunotherapies have produced promising results. Although traditionally considered unresponsive to immune therapy, increa ...
Modulation of tumor immunity by ...
The surveillance of tumors by the immune system of cancer patients and its impact on disease progression and patient survival have been largely docu ...
Immunomodulating antibodies and ...
The aim of cancer immunotherapy is to induce immune cells to kill tumor and promote immunological memory that protects against tumor recurrence. Mos ...
Angiogenesis and immunity: a bi ...
The immune system regulates angiogenesis in cancer with both pro- and antiangiogenic activities. The induction of angiogenesis is mediated by tumor- ...
How to improve the immunogenici ...
Chemotherapy or radiotherapy could induce various tumor cell death modalities, releasing tumorderived antigen as well as danger signals that could e ...
The heparanase system and tumor ...
Tumor metastasis, the leading cause of cancer patients’ death, is still insufficiently understood. While concepts and mechanisms of tumor metastasis ...
Molecular determinants of immun ...
The success of some chemo- and radiotherapeutic regimens relies on the induction of immunogenic tumor cell death and on the induction of an anticanc ...
The role of nuclear pore comple ...
One of the main reasons for cancer mortality is caused by the highly invasive behavior of cancer cells, which often due to aggressive metastasis. Me ...
Future perspectives on neuroend ...
In the last 30 years the incidence and prevalence of gastroenteropancreatic neuroendocrine tumors (GEPNETs) has increased substantially. This could ...
The significant role of mast ce ...
Mast cells (MC) are a bone marrow-derived, long-lived, heterogeneous cellular population that function both as positive and negative regulators of i ...
Morphine and tumor growth and m ...
Morphine is an analgesic widely used to alleviate cancer pain. In addition, the perioperative management of pain in cancer surgery patients most oft ...
Innovations therapy: mammalian ...
Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are rare neoplasms that require a multidisciplinary approach for an optimal management. The ...
Myeloid cell diversification an ...
Tumour development is accompanied by an enhanced haematopoiesis. This is not a widespread activation since only cells belonging to the myelo-monocyt ...
Microbial deprivation, inflamma ...
Dysregulated immune function is involved in the pathogenesis of many common human diseases. Living in urban, microbe-poor environment may have a pro ...
Therapy innovations: tyrosine k ...
Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) show limited sensitivity to cytotoxic agents, requiring the search for novel therapies. Rece ...
DNA repair: the culprit for tum ...
The existence of “tumor-initiating cells” (TICs) has been a topic of heated debate for the last few years within the field of cancer biology. Their ...
Tumor microenvironment is multi ...
Cancer initiation, progression, and invasion occur in a complex and dynamic microenvironment which depends on the hosts and sites where tumors devel ...
Somatostatin analogs for the tr ...
Somatostatin is an important regulator of endocrine and exocrine secretion, affecting the release of many hormones. The effects of somatostatin are ...
Mast cell: insight into remodel ...
Mast cells are of paramount importance to allergies, pathogen immune responses during infections, and angiogenesis, as well as innate and adaptive i ...
Current knowledge on diagnosis ...
Neuroendocrine tumors (NETs) consist of a heterogeneous group of malignancies with various clinical presentations and growth rates. The incidence ha ...
True local recurrences do not m ...
Generally, the limits of local tumor control are in part connected with the term “field cancerization” and are known from oral, lung, prostate, or m ...
External validation of a model ...
The surgical treatment of spinal metastases is evolving. The major problem is the selection of patients who may benefit from surgical treatment. One ...
Transcutaneous detection and di ...
Background Indocyanine green (ICG) fluorescence navigation is a useful option in sentinel node biopsy (SNB) for breast cancer. However, several tech ...