Polymorphisms in the ALOX12 gene and osteoporosis
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Polymorphisms in the ALOX12 gen ...
Summary ALOX12 produces ligands for PPARγ thereby turning mesenchymal stem cells into adipocytes instead of osteoblasts. We investigated the effect ...
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A critical review of racial/eth ...
Summary Racial and ethnic variables are common in research on variation in bone density. This literature review describes some of the common flaws a ...
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Osteoporosis quality indicators ...
Summary Healthcare utilization data may be used to examine the quality of osteoporosis management by identifying dual-energy X-ray absorptiometry (D ...
142.75 KB
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Systemic bone effects of biolog ...
Inflammatory joint diseases are responsible of chronic systemic inflammation, joint degradations, deformities, and altered quality of life. Patients ...
776.04 KB
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Development and validation of a ...
Summary This article describes the development of a model for postmenopausal osteoporosis (PMO) based on Swedish data that is easily adaptable to ot ...
514.49 KB
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Do RANKL inhibitors (denosumab) ...
Receptor activator of nuclear factor kappa B ligand (RANKL) and its natural antagonist, osteoprotegerin (OPG), are, respectively, an indispensable f ...
322.30 KB
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Validation of a case definition ...
Summary A simple case definition for osteoporosis case diagnosis is feasible based upon administrative health data. This may facilitate implementati ...
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Lifestyle factors, medications, ...
Summary Aging alone is not the only factor accounting for poor bone health in older men. There are modifiable factors and lifestyle choices that may ...
226.69 KB
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How strontium ranelate, via opp ...
Oestrogen deficiency increases the rate of bone remodelling which, in association with a negative remodelling balance (resorption exceeding formatio ...
251.69 KB
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Does birthweight predict bone m ...
Summary This systematic review and meta-analysis assessed the strength and magnitude of the association between birthweight and adult bone mass. Hig ...
194.83 KB
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Prevalence of vitamin D deficie ...
Summary Vitamin D status of nonwestern immigrants in Europe was poor. Vitamin D status of nonwestern populations in their countries of origin varied ...
209.54 KB
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Effects of therapeutic exercise ...
Summary A systematic literature review was conducted and revealed nine studies investigating the effects of therapeutic exercise for persons with os ...
245.85 KB
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Osteoporosis in inflammatory jo ...
Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) are two inflammatory joint diseases characterized by bone complications including osteopor ...
294.49 KB
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Failure to perceive increased r ...
Summary We compared self-perception of fracture risk with actual risk among 60,393 postmenopausal women aged .55 years, using data from the Global L ...
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Exercise prescription after fra ...
The purpose of this study is to identify and chart research literature on safety, efficacy, or effectiveness of exercise prescription following frac ...
500.92 KB
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Efficacy, side effects and rout ...
The purposes of the study were to review available published literature on magnitude of non-adherence with osteoporosis regimens and to determine th ...
289.93 KB
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Markers of bone turnover for th ...
Summary The International Osteoporosis Foundation (IOF) and the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) recomm ...
458.46 KB
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Oral bisphosphonate compliance ...
Compliance to oral bisphosphonates is suboptimal, with negative consequences of increased healthcare utilization and less effective fracture risk re ...
117.58 KB
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Subtrochanteric fractures after ...
Summary This paper reviews the evidence for an association between atypical subtrochanteric fractures and longterm bisphosphonate use. Clinical case ...
306.71 KB
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BMI change is associated with f ...
Summary Few studies have examined the association between body mass index (BMI) change and fracture in a general population. We observed that BMI lo ...
164.73 KB
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Spine–hip discordance and fract ...
Summary The FRAX® tool estimates a 10-year probability of fracture based upon multiple clinical risk factors and an optional bone mineral density (B ...
169.97 KB
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New knowledge on critical osteo ...
Functional, biochemical and genetic studies have over the past decade identified many causative genes in the osteoclast diseases osteopetrosis and P ...
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753.90 KB
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Influence of physical activity ...
The research protocol was reviewed by the Ethics Committee of the University Hospital of Oulu. MRI scans were obtained with a 1.5-T unit (Sigma, Ge ...
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Denosumab-related osteonecrosis ...
The case of a cancer patient who developed ONJ without previous history of irradiation or bisphosphonate administration has been published [6]. In t ...
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Zoledronic acid-induced transie ...
Bisphosphonate (BP)-induced hepatotoxicity is very rare. There are only a few reports of liver injury after BP treatment, including aledronate and r ...
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