Therapeutic Implications of a Barrier-Based Pathogenesi ...
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Therapeutic Implications of a B ...
Excessive Th2 cell signaling and IgE production play key roles in the pathogenesis of atopic dermatitis (AD). Yet, recent information suggests that ...
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Auto-antibodies as Emergent Pro ...
During the last 15 years, a growing body of evidence supported the fact that auto-antibodies represent not only emergent markers but also active med ...
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Cutting Edge Issues in Autoimmu ...
Autoimmune gastritis is the outcome of a pathological CD4 T cell-mediated autoimmune response directed against the gastric H/K-ATPase. Silent initia ...
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Genetics and Immunopathogenesis ...
IgA nephropathy (IgAN) is the most common glomerulonephritis in the world. The hallmark of IgAN is underglycosylation in the hinge region of IgA1. I ...
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Cutting-Edge Issues in Celiac D ...
Celiac disease (CD) is a gluten-dependent immune-mediated disease with a prevalence in the general population estimated between 0.3% and 1.2%. Large ...
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Cutting Edge Issues in Polymyos ...
Skeletal muscle is the target tissue of immunoflogistic processes in patients affected with idiopathic inflammatory myopathies (IIM). IIM are classi ...
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Viruses and Cytotoxic T Lymphoc ...
Histopathological studies on pancreas tissues from individuals with recent-onset type 1 diabetes (T1D) consistently find that CD8 T cells substantia ...
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The Diagnostic and Clinical Sig ...
The role of autoimmunity in cardiovascular diseases has become one of the focal points of research studies. Autoimmune response and autoreactive aut ...
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Role of Dendritic Cells in Atop ...
Dendritic cells (DCs) have been recognized as key players bridging innate and adaptive immune systems. They control the balance of the adaptive immu ...
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Cutting Edge Issues in Goodpast ...
Goodpasture’s disease, or anti-glomerular basement membrane (anti-GBM) disease, is a systemic autoimmune disorder defined by anti-GBM antibody-media ...
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Macrophagic Myofaciitis a Vacci ...
Macrophagic myofasciitis (MMF) is an immunemediated condition first reported in 1998. MMF is characterized by post-vaccination systemic manifestatio ...
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Innate Immunity in Atopic Derma ...
Atopic dermatitis (AD) is a clinically defined, highly pruritic, chronic inflammatory skin disease. In AD patients, the combination of a genetic pre ...
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Pruritus and Atopic Dermatitis
Atopic eczema is one of the most pruritic skin diseases. Mediators of atopic eczema itch in the skin are still mostly unknown, but recent studies sh ...
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Guillain–Barré Syndrome—A Class ...
Guillain–Barré syndrome (GBS) is a rare autoimmune disorder, the incidence of which is estimated to be 0.6–4/100,000 person/year worldwide. Often, G ...
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Atopic Dermatitis and the Nervo ...
Due to the narrow associations between the skin, immune system, and nervous system, nerve endings are very important in the pathophysiology of infla ...
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Recent Concepts of Autoimmune P ...
Recent studies suggested the existence of two subtypes of autoimmune pancreatitis (AIP): type 1 related with IgG4 (lymphoplasmacytic sclerosing panc ...
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Overcoming a “Probable” Diagnos ...
Serum anti-mitochondrial antibodies (AMA) are the serological hallmark of primary biliary cirrhosis (PBC), yet up to 15% of PBC sera are AMA negativ ...
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Cutting Edge Issues in Primary ...
Primary sclerosing cholangitis (PSC) is a chronic inflammatory liver disease characterized by the destruction of medium- to large-sized bile ducts a ...
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Therapeutic Perspectives in Ato ...
Therapy of atopic dermatitis should comprise emollients, topical glucocorticosteroids, or calcineurin inhibitors, phototherapies, immunosuppressants ...
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The Clinical Significance of An ...
Autoimmune response against myocardial antigens is evident in numerous heart diseases. Both the induction of an autoimmune response and the pathogen ...
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Role of Autoimmunity and Autoin ...
Idiopathic recurrent pericarditis is the most common and troublesome complication of acute pericarditis affecting about one third of such patients. ...
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Transforming growth factor beta ...
Purpose Atrial fibrillation (AF) and acute congestive heart failure (aCHF) are characterized by an adverse cardiac remodeling. Arrhythmogenic or str ...
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New-onset versus chronic atrial ...
Aims Atrial fibrillation (AF) occurs commonly in patients with acute myocardial infarction (AMI) and has been established as a marker of adverse pro ...
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Influence of acute and chronic ...
Background We compared the effect of different loading conditions, parameters of structural heart disease and extracardiac confounders on NT-proBNP ...
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Vascular remodeling in adults a ...
Background Patients after successful repair of coarctation of aorta (CoAo) are at risk of hypertension at rest and associated end-organ damage. The ...
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