Women and Alport syndrome
Should we consider MMF therapy ...
The management of steroid-dependent nephrotic syndrome, especially in patients who have failed to respond to cytotoxic drugs, such as cyclophosphami ...
Parathyroid hormone levels in l ...
Secondary hyperparathyroidism is a common complication of chronic renal failure. Kidney transplantation corrects renal insufficiency and most metabo ...
Comparative clinical outcomes b ...
Published data on the comparative achievement of The Kidney Disease Dialysis Outcome Quality Initative (KDOQI) recommended clinical performance targ ...
Novel developments in thromboti ...
Thrombotic microangiopathies (TMA) represent a spectrum of related disorders associated with newly formed thrombi that block perfusion and thus affe ...
Physiopathology of idiopathic n ...
Idiopathic nephrotic syndrome (INS) has been studied for decades in attempt to understand the physiopathological mechanisms explaining the disease. ...
The role of serum myeloid-relat ...
Myeloid-related protein (MRP) 8/14 complex is a marker of monocyte and neutrophil activation. We evaluated whether serum MRP8/14 complex is associat ...
Phenotypic variability of Barde ...
Bardet-Biedl syndrome (BBS) is a multisystemic developmental disorder diagnosed on the basis of the presence of obesity, retinal defects, polydactyl ...
Microalbuminuria: causes and im ...
Management strategies are increasingly focused on tackling the increasing burden of cardiovascular disease worldwide. Microalbuminuria is a powerful ...
Women and Alport syndrome
X-linked Alport syndrome (XLAS) is caused by mutations in type IV collagen causing sensorineural hearing loss, eye abnormalities, and progressive ki ...
Dyslipidemia in children with C ...
Dyslipidemia has been shown to be a risk factor for increased cardiovascular morbidity and mortality in adult patients with chronic kidney disease ( ...
Cardiorespiratory fitness in yo ...
Limited knowledge exists on cardiorespiratory fitness (CR fitness) in adults having a renal transplant (Rtx) during childhood. Our aim was to assess ...
Maintenance therapy with mycoph ...
Rituximab (RTX) has a significant steroidsparing effect in children with steroid-dependent nephrotic syndrome (SDNS). However, patients are likely t ...
Nephrotic syndrome in infancy c ...
Nephrotic syndrome in the first year of life (NSFL) is a heterogeneous group of disorders, the management of which is supportive, as most patients d ...
Insufficient protection by Neis ...
Sirs, Spurred by the reported spectacular results of eculizumab treatment in atypical hemolytic uremic syndrome (aHUS) due to aberrations in the co ...
The role of molecular genetics ...
Familial microscopic hematuria (MH) of glomerular origin represents a heterogeneous group of monogenic conditions involving several genes, some of w ...
Epidemiology of chronic kidney ...
In the past 30 years there have been major improvements in the care of children with chronic kidney disease (CKD). However, most of the available ep ...
Weight or body surface area dos ...
Although prednisone is the treatment of choice for nephrotic syndrome (NS) in childhood, the dosing regimen varies between 60 mg/m2/day, as recommen ...
Rhabdomyolysis: pathogenesis of ...
Rhabdomyolysis refers to the breakdown of skeletal muscle due to either a physical, biological, or toxic injury that leads to leakage of muscle cont ...
A patient with polyuria and hyd ...
The case demonstrates the importance of assessing NDI and hydronephrosis separately. Hydronephrosis is a recognised complication of primary NDI and ...
Heart ventricular activation in ...
Children with chronic kidney disease (CKD) are affected by cardiovascular complications, including disturbances in the intraventricular conduction s ...
The impact of vesicoureteral re ...
Vesicoureteral reflux (VUR) is a heterogeneous disease and its management remains one of the most controversial topics in pediatrics. Management opt ...
Postnatal trends in creatinemia ...
To document trends and covariates of creatinemia (Scr) in extremely low birth weight (ELBW, < 1,000 g) neonates, maternal characteristics [betametha ...
Neurological development in 21 ...
Few studies have focused on the neurodevelopment of infants on peritoneal dialysis (PD). Infants are the most demanding patient group on PD and thus ...
Posterior reversible encephalop ...
Posterior reversible encephalopathy syndrome (PRES) was originally used to describe a reversible, predominantly posterior leukoencephalopathy in pat ...
Why is hypercalciuria absent at ...
We try to explain why hypercalciuria is absent at diagnosis in some children with an ATP6V1B1 mutation. A 5-month-old girl presented with distal ren ...