Paroxysmal nocturnal hemoglobinuria (PNH): higher sensi ...
رایگان
Paroxysmal nocturnal hemoglobin ...
Flow cytometric analysis of GPI-anchored proteins (GPI-AP) is the gold standard for diagnosis of paroxysmal nocturnal hemoglobinuria (PNH). Due to ...
دانلود 1
1.23 MB
رایگان
Anti-annexin V IgG and IgM anti ...
Vaso-occlusive crisis (VOC) is a significant cause of morbidity and mortality in sickle cell anemia (SCA) patients; however, its mechanisms are poor ...
132.21 KB
رایگان
Severe congenital neutropenia i ...
We have analysed a family with nine congenital neutropenia patients in four generations, several of which we have studied in a long-term follow-up o ...
217.88 KB
رایگان
Sickle-cell disease and malaria ...
Sickle-cell disease (SCD) patients are at high risk of developing malaria which is a major contributor to morbidity andmortality in this disease. In ...
111.05 KB
رایگان
CYP2B6 gene single nucleotide p ...
CYP2B6 is a highly variable and polymorphic cytochrome P450 enzyme which plays a vital role in the degradation of some endogenous metabolites, xenob ...
203.14 KB
رایگان
Long-term follow-up of patients ...
Prior to introduction of imatinib mesylate, the median survival of chronic myeloid leukemia (CML) patients was approximately 60 months and the stand ...
208.90 KB
رایگان
Danazol as first-line therapy f ...
Immunosuppressive therapy (IST) with antithymocyte globulin (ATG) plus cyclosporine A (CsA) is the standard treatment for aplastic anemia (AA) patie ...
149.17 KB
رایگان
Overexpression of the EZH2, RIN ...
Epigenetics refers to the study of clonally inherited changes in gene expression without accompanying genetic changes. Previous research on the epig ...
348.51 KB
رایگان
Chronic nonspherocytic hemolyti ...
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is one of the most common hereditary enzymopathies worldwide. Mostly G6PD deficient cases are a ...
137.89 KB
رایگان
In situ RHAMM protein expressio ...
Treatment options for patients with high-risk acute myeloid leukemia (AML) include high-dose chemotherapy regimens in combination with allogeneic he ...
470.31 KB
رایگان
Polo-like kinase 2 (SNK/PLK2) i ...
Polo-like kinase 2 (SNK/PLK2), a transcriptional target for wild-type p53 and is hypermethylated in a high percentage of multiple myeloma and B cell ...
246.79 KB
رایگان
High prevalence of hepatitis B ...
We performed a large case–control study (3,932 cases, 15,562 controls) to investigate the association of hepatitis B virus (HBV) and hepatitis C vir ...
109.81 KB
رایگان
Prevalence of H63D, S65C, and C ...
Hereditary HFE Hemochromatosis is an inherited disorder of iron metabolism that results from mutations in the HFE gene. Almost all patients with her ...
99.69 KB
رایگان
Long-term outcome of hemizygous ...
The transcriptional regulator GATA1 is crucially involved in megakaryocytopoiesis and erythropoiesis. Mutations of the gene which is located on the ...
643.92 KB
رایگان
CLIPI: a new prognostic index f ...
Indolent primary cutaneous B cell lymphomas (PCBCL) generally have a good prognosis, but they often relapse leading in some cases to extracutaneous ...
245.04 KB
رایگان
Long-term follow-up of clonal e ...
To assess the incidence rates and risk factors for clonal evolutions in aplastic anemia (AA) patients, we studied 802 hospitalization cases from Jan ...
266.57 KB
رایگان
Iron status and treatment modal ...
Transfusion dependency and iron overload are common among patients with myelodysplastic syndromes (MDS) treated with red blood cell (RBC) transfusio ...
437.67 KB
رایگان
Alkylating chemotherapeutic age ...
The adverse effects of melphalan and cyclophosphamide on hematopoietic stem cells are well-known; however, the effects on the mesenchymal stem cells ...
594.42 KB
رایگان
Intrathecal application of dono ...
Extramedullary relapses after allogeneic stem cell transplantation, especially within the central nervous system (CNS), are not only difficult to tr ...
215.52 KB
رایگان
Elevated frequencies of leukemi ...
Some 30% of acute myeloid leukemia (AML) patients display an internal tandem duplication (ITD) mutation in the FMS-like tyrosine kinase 3 (FLT3) gen ...
717.92 KB
رایگان
The role of routine imaging pro ...
Despite improved initial therapies, a subgroup of patients with aggressive non-Hodgkin (A-NHL) and Hodgkin lymphomas (HL) will relapse after first r ...
170.78 KB
رایگان
Expression of myelopoiesis-asso ...
The microRNA/miR deregulation in BCR-ABLnegative myelodysplastic-myeloproliferative neoplasms (MDS/MPN) is not known. Myelopoiesis-associated miR-1 ...
189.35 KB
رایگان
Thrombospondin-1 (TSP-1) in pri ...
Primary myelofibrosis (PMF) is a chronic myeloproliferative neoplasm showing aberrant bone marrow remodeling with increased angiogenesis, progressiv ...
511.56 KB
رایگان
Indoleamine 2,3-dioxygenase in ...
Indoleamine 2,3-dioxygenase (IDO) exerts immunomodulatory effects due to enzymatic activities catalyzing the essential amino acid L-tryptophan. IDO ...
352.49 KB
رایگان
Secondary central nervous syste ...
Secondary central nervous system (CNS) involvement in diffuse large B-cell lymphoma (DLBCL) includes an isolated CNS relapse or CNS involvement with ...
233.16 KB
رایگان
