Treatment of Refractory Status Epilepticus in Childhood
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Treatment of Refractory Status ...
Refractory status epilepticus (RSE) is characterized by a prolonged seizure that persists despite adequate initial management. RSE accounts for almo ...
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Current State of Our Knowledge ...
The overall incidence of brain tumors for benign and malignant tumors combined is 18.71 per 100,000 person-years; 11.52 per 100,000 person-years for ...
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Antiepileptic Drugs and Neurode ...
In utero exposure to some antiepileptic drugs (AEDs) is associated with an increased risk of impaired cognitive development. Specifically, valproate ...
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Lipid Storage Myopathy
Lipid storage myopathy (LSM) is pathologically characterized by prominent lipid accumulation in muscle fibers due to lipid dysmetabolism. Although e ...
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Neurocritical Care of a Reperfu ...
Cerebral hyperperfusion and reperfusion injuries are not infrequently encountered following in reperfusion of ischemic or hypoperfused brain.Mechani ...
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Newly Postulated Neurodevelopme ...
Recent animal and human studies have raised concern that exposure to anesthetic agents in children may cause neuronal damage and be associated with ...
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Advances in MRI Assessment of G ...
Bevacizumab is thought to normalize tumor vasculature and restore the blood–brain barrier, decreasing enhancement and peritumoral edema. Conventiona ...
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Epilepsy and Autism: Neurodevel ...
Epilepsy and autism coexist in up to 20% of children with either disorder. Current studies suggest that a frequent co-occurring condition in epileps ...
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Prognosis After Cardiac Arrest ...
Before the use of hypothermia as a treatment for comatose post-cardiac arrest patients, several prognostic variables were widely accepted as reliabl ...
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Asymptomatic Sleep Abnormalitie ...
Huntington’s disease (HD) is a fatal neurodegenerative disease characterized bymotor, cognitive, and psychiatric disturbance. In this article, we us ...
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Hormonal Therapy for Epilepsy
In 2011, there are greater than 20 antiepileptic medications available. These medications work by modulating neuronal excitability. Reproductive hor ...
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The Sleep Manifestations of Fro ...
Frontal lobe seizures have a tendency to occur from sleep, and in some cases occur exclusively (or almost exclusively) from sleep; these individuals ...
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Biofeedback and Epilepsy
Biofeedback is a noninvasive behavioral treatment that enables a patient to gain volitional control over a physiological process. As a treatment for ...
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Hypocretin and Its Emerging Rol ...
The neuropeptides hypocretin-1 and -2 (orexin A and B) are critical in the regulation of arousal and maintenance of wakefulness. Understanding the r ...
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The Pathophysiologic Basis of S ...
The symptoms of narcolepsy can occur during the course of other neurologic conditions (ie, symptomatic narcolepsy). Inherited disorders, tumors, and ...
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Fingolimod for Multiple Scleros ...
The oral sphingosine 1-phosphate receptor (S1PR) modulator fingolimod functionally antagonizes S1PR hereby blocking lymphocyte egress from secondary ...
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Gait Abnormalities in Multiple ...
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system characterized by episodic decline in various neurologic functions. ...
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The Radiologically Isolated Syn ...
The advent and wide use of magnetic resonance brain imaging has led to in the unexpected detection of lesions that appear typical of multiple sclero ...
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Role of Cerebrospinal Fluid and ...
Biomarkers are one type of laboratory testing being developed in response to the therapeutic imperative for diseases that cause cognitive impairment ...
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Pharmacogenomics and Multiple S ...
Notwithstanding the availability of diseasemodifying treatments including interferon-β, glatiramer acetate, and natalizumab, a considerable proporti ...
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Advances in Epigenetics and Epi ...
In the post-genomic era, epigenetic factors— literally those that are “over” or “above” genetic ones and responsible for controlling the expression ...
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Denosumab in Breast Cancer
Bone destruction is mediated by osteoclasts, whose formation, function, and survival requires the receptor activator of NF-kB ligand (RANKL). Denosu ...
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Update: Modern Approaches to th ...
The optimal treatment strategy for esophageal cancer continues to be a topic of debate. Improvements in chemotherapy drugs, surgical techniques, and ...
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The Need for Axillary Dissectio ...
The need for completion axillary dissection after a positive sentinel node biopsy continues to be challenged. In the 2 years since we last reviewed ...
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Commentary: Implications of Can ...
In an increasing number of settings it is appropriate to consider cancer as a very serious but also a chronic disease process. This commentary discu ...
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