Children’s rights in pediatrics
The United Nations Convention of Children’s Rights (UNCRC) introduced in 1989 has generated a global movement for the protection of children’s right ...
Biologics in children’s autoimm ...
Advances in understanding the pathogenesis of rheumatic diseases have led to the discovery of mechanisms of inflammation and autoimmunity and have m ...
Clinical practice Proteinuria
Proteinuria detection in children is a challenge. Five percent to 15% and 0.4–1% of school children present either transient (benign) or persistent ...
Educational paper Screening in ...
Improvements in our understanding of the genetic basis of human disease and increased utilization of genetic testing have identified a variety of he ...
Eponym de Quervain thyroiditis
de Quervain thyroiditis is a self-limited inflammatory disorder of the thyroid gland. It is an uncommon disease in adults and very rare in children. ...
Educational paper The expanding ...
Severe combined immunodeficiency (SCID) is one of the most severe forms of primary immunodeficiency characterized by absence of functional T lymphoc ...
Educational paper Primary antib ...
Primary antibody deficiencies (PADs) are the most common primary immunodeficiencies and are characterized by a defect in the production of normal am ...
Assessing pain in ventilated ne ...
The Hartwig score was designed to assess pain in ventilated newborns and infants. It comprises the acceptance of mechanical ventilation and the reac ...
Respiratory morbidity, healthca ...
The aim of the study was to determine whether respiratory morbidity, lung function, healthcare utilisation and cost of care at school age in prematu ...
Educational paper Primary immun ...
Primary immunodeficiencies (PIDs) are characterized by an increased susceptibility to infections due to defects in one ore more components of the im ...
Clinical practice The managemen ...
Hyperammonemia is a life-threatening condition which can affect patients at any age. Elevations of ammonia in plasma indicate its increased producti ...
Educational paper Syndromic for ...
The syndromic primary immunodeficiencies are disorders in which not only the immune system but also other organ systems are affected. Other features ...
Aerosol delivery to ventilated ...
There are several aerosolized drugs which have been used in the treatment of neonatal respiratory illnesses, such as bronchodilators, diuretics, and ...
Neonatal liver failure: aetiolo ...
Acute liver failure in neonates is rare, but carries a high mortality. Neonatal liver failure can be defined as “failure of the synthetic function o ...
Educational paper The effect of ...
Over the past several decades, pediatric oncologists have seen the growth in the number of patients surviving their cancer. This is in large part du ...
Metabolic, inflammatory, endoth ...
Childhood obesity and its related comorbidities are increasingly recognised in children, predisposing them to early cardiovascular disease and metab ...
Measurements of neonatal biliru ...
Accurate and precise bilirubin and albumin measurements are essential for proper management of jaundiced neonates. Data hereon are lacking for Dutch ...
Eponym Johanson-Blizzard syndro ...
Johanson-Blizzard syndrome is a very rare autosomal recessive disorder caused by mutations in the Ubiquitin-Protein Ligase E3 Component N-Recognin 1 ...
Position paper—HPV and the prim ...
A large proportion of sexually active adults are infected with the human papillomaviruses (HPVs). Although largely asymptomatic, some types of HPVs ...
Preliminary data on the associa ...
The aim of the present work was to study the association between different anthropometric parameters and insulin resistance (IR) in Spanish schoolch ...
The Eurofever Project: towards ...
Autoinflammatory diseases are a group of diseases characterized by inflammatory attacks. The monogenic forms of these diseases are also classified a ...
Over-the-counter drug use—estim ...
We have used three different sources to estimate the use of drugs sold over the counter (OTC) by the Swedish paediatric population during 2007–2008 ...
Inhaled corticosteroids in chil ...
Inhaled corticosteroids (ICS) are the most effective anti-inflammatory drugs for the treatment of persistent asthma in children. Treatment with ICS ...
Detection of Mycoplasma pneumon ...
Mycoplasma pneumoniae (M. pneumoniae) is an important community-acquired pneumonia pathogen. Serological test and polymerase chain reaction (PCR) as ...
Autoimmune thyroid disease in L ...
Diabetes mellitus is a common autoimmune endocrine disorder associated with organ-specific autoantibodies which are frequently detected at the time ...