A practical approach to imaging ...
Cardiac resynchronization therapy (CRT) is believed to benefit patients by primarily correcting heterogeneity in regional ventricular mechanical con ...
Implantable cardioverter-defibr ...
Implantable cardioverter-defibrillators have proven efficacy in reducing mortality in patients with reduced left ventricular ejection fraction in bo ...
TNFa in myocardial ischemia/rep ...
TNFa is crucially involved in the pathogenesis and progression of myocardial ischemia/reperfusion injury and heart failure. The formation and releas ...
Histopathology of the stimulate ...
A primary concern in the utilization of implantable neural interfaces for the treatment of medical diseases is to follow the Hippocratic dictum: Fir ...
Atrioventricular and interventr ...
In this review, the physiological rationale for atrioventricular and interventricular delay optimization of cardiac resynchronization therapy is dis ...
The role of nuclear imaging in ...
Heart failure represents a common disease affecting approximately 5 million patients in the United States. Several conditions play an important role ...
The potential role of cardiac r ...
Cardiac resynchronization therapy (CRT) has been demonstrated to improve mortality and morbidity in patients with chronic, stable heart failure who ...
Innate immunity and remodelling
A wide variety of cardiac disease states can induce remodelling and lead to the functional consequence of heart failure. These complex disease state ...
Vagus nerve stimulation in expe ...
Chronic heart failure (HF) is associated with autonomic dysregulation characterized by a sustained increase in sympathetic drive and by withdrawal o ...
When is an optimization not an ...
Impact of variability in the measured parameter is rarely considered in designing clinical protocols for optimization of atrioventricular (AV) or in ...
Erratum to: Resveratrol and red ...
Resveratrol, a polyphenol phytoalexin, present in red wine and grapes possesses diverse biochemical and physiological properties, including estrogen ...
Device monitoring strategies in ...
Acute heart failure syndromes (AHFS) represent the most common discharge diagnoses in adults over age 65 and translate into dramatically increased h ...
New insights into the role of t ...
Chronic ischemia or pressure overload decreases thyroid hormone (TH) signaling and activates the fetal gene program in the heart. While these featur ...
Pharmacologic modulation of par ...
In the congestive heart failure state, autonomic dysregulation involves an increase in sympathetic tone and decrease in parasympathetic tone and is ...
Lead positioning strategies to ...
Left ventricular lead position is one of the main determinants of CRT response. There are several approaches in LV lead positioning that include fav ...
Vagus nerve stimulation: from p ...
Vagus nerve stimulation was performed experimentally for the first time more than 150 years ago. In the 1980s and 1990s, vagus nerve stimulation was ...
Chronic ventricular pacing in c ...
In children with congenital or acquired complete atrioventricular (AV) block, ventricular pacing is indicated to increase heart rate. Ventricular pa ...
Electrical modalities beyond pa ...
In this review, we report on electrical modalities, which do not fit the definition of pacemaker, but increase cardiac performance either by direct ...
Heart failure with preserved ej ...
Heart failure is an epidemic in the elderly and has become a leading cause for hospitalization and death. Heart failure with preserved ejection frac ...
Role of various proteases in ca ...
It is believed that cardiac remodeling due to geometric and structural changes is a majormechanism for the progression of heart failure in different ...
Cystatin C: a step forward in a ...
The cardiorenal syndrome is a clinical manifestation of the bidirectional interaction between the heart and kidneys. Evaluating renal function is an ...
Emerging therapies for heart fa ...
Improved understanding of the pathophysiology of salt and water homeostasis has provided a foundation for explaining the renal mechanisms of emergin ...
Tissue inhibitor of metalloprot ...
Remodeling of the myocardium and the extracellular matrix (ECM) occurs in heart failure irrespective of its initial cause. The ECM serves as a scaff ...
New roles for renin and proreni ...
The renin-angiotensin-aldosterone-system (RAAS) plays a central role in the pathophysiology of heart failure and cardiorenal interaction. Drugs inte ...
Pharmacotherapy of heart failur ...
Aging is associated with numerous alterations in body composition and organ function that result in substantial changes in the absorption, distribut ...