Using HLA-A2.1 Transgenic Rabbit Model to Screen and C ...
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Using HLA-A2.1 Transgenic Rabbi ...
We have established an HLA-A2.1 transgenic rabbit /cottontail rabbit papillomavirus (CRPV) infection model. Using this novel transgenic animal model, ...
1.32 MB
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Can Systems Biology Understand ...
Cancer is thought to be caused by a sequence of multiple genetic and epigenetic alterations which occur in one or more of the genes controlling cell ...
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Mitochondrial and Nuclear Genes ...
Although the observation of aerobic glycolysis of tumor cells by Otto v. Warburg had demonstrated abnormalities of mitochondrial energy metabolism in ...
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Computational Challenges of Per ...
It is widely predicted that cost and efficiency gains in sequencing will usher in an era of personal genomics and personalized, predictive, preventiv ...
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Activation and Costimulation of ...
T cells are present in large numbers in the epithelial lining of the small and large intestine of humans and mice. Those cells, referred to as intrae ...
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High-Throughput Omics Technolog ...
The mode of action of a huge amount of agents on biological systems is still unknown. One example where more questions than answers exist is covered ...
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Current Screens Based on the Al ...
Global deciphering of signal transduction pathways represents a new challenge of the post-genomic era. However, for the majority of these signaling p ...
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Innate Immunity in the Skin: Ho ...
The human skin is constantly exposed to a large number of external pathogens, due to the daily contact with the environment. The observation that ext ...
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Plant Spliceosomal Introns: Not ...
Spliceosomal introns in higher eukaryotes are present in a high percentage of protein coding genes and represent a high proportion of transcribed nuc ...
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Genome Analysis of Food Grade L ...
Whole-genome sequencing has revolutionized and accelerated scientific research that aims to study the genetics, biochemistry and molecular biology of ...
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Gene Expression and Regulation ...
Higher plants not only provide human beings renewable food, building materials and energy, but also play the most important role in keeping a stable ...
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Effect of Pre-Existing Immunity ...
We previously demonstrated that a DNA-based tetravalent dengue vaccine can induce balanced neutralizing antibody responses against all four types of ...
1.12 MB
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The Potential Role of Pharmacog ...
Although notable progress has been made in the treatment of non-small-cell lung cancer (NSCLC) in recent years, this disease is still associated with ...
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MicroRNA and Cancer: Tiny Molec ...
Cancer is currently a major public health problem and, as such, emerging research is making significant progress in identifying major players in its ...
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Functional and Clinical Evidenc ...
We searched for potential suppressors of tumor metastasis by identifying the genes that are frequently down-regulated in hepatocellular carcinomas ( ...
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Post-Translational Control of S ...
Sp-family transcription factors are widely expressed in human tissues and involved in the regulation of many cellular processes and response to cellu ...
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Systems Behavior: Of Male Court ...
Male courtship in fruit flies is regulated by the same major regulatory genes that also determine general sexual differentiation of the animal. Elabo ...
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Episcopic 3D Imaging Methods: T ...
This work aims at describing episcopic 3D imaging methods and at discussing how these methods can contribute to researching the genetic mechanisms dr ...
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Molecular Cytogenetics and Cyto ...
Molecular cytogenetics is a promising field of biomedical research that has recently revolutionized our thinking on genome structure and behavior. Th ...
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Meta Analysis of Gene Expressio ...
Since the second half of the 1990s, a large number of genome-wide analyses have been described that study gene expression at the transcript level. To ...
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New Insights into the Modulatio ...
Fasciola hepatica is a trematode that affects human and domestic ruminant health, causing significant economic losses in cattle estimated at US$2000 ...
دانلود 1
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Type 2 Diabetes Mellitus: New G ...
Type 2 diabetes is a disorder of dysregulated glucose homeostasis. Normal glucose homeostasis is a complex process involving several interacting mech ...
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Understanding Genetic Factors i ...
Idiopathic scoliosis (AIS) is the most common pediatric spinal deformity, affecting ~3% of children worldwide. AIS significantly impacts national hea ...
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The Protection Potential of an ...
Aluminum hydroxide is the only adjuvant for use in human vaccines. The commercial alum-adjuvanted vaccines are formulated as liquid without exception ...
1.88 MB
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Involvement of Nucleotide Excis ...
Living organisms are constantly threatened by environmental DNA-damaging agents, including UV and ionizing radiation (IR). Repair of various forms of ...
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