Coronary spasm after completion of adenosine pharmacolo ...
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Coronary spasm after completion ...
Adenosine is a frequently used pharmacologic stress agent in myocardial perfusion imaging. Its safety profile is well established, and most of its s ...
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Prediction of lack of response ...
The authors report a case of a 47-year-old female with a malignant lump in the right breast and ipsilateral axillary nodal involvement. She was path ...
253.85 KB
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Glycogen synthase kinase 3 beta ...
The role of glycogen synthase kinase 3 beta (GSK-3b) in modulating Notch control of vascular smooth muscle cell (vSMC) growth (proliferation and apo ...
795.46 KB
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Mitochondria to nucleus translo ...
Heat shock protein 70 (Hsp70) has been shown to have an anti-apoptotic function, but its mechanism is not clear in heart. In this study, we examined ...
711.72 KB
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Clopidogrel improves endothelia ...
Clopidogrel treatment in patients with coronary artery disease not only inhibits platelet activation but also improves endothelial function and nitr ...
411.89 KB
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Effects of high thoracic epidur ...
High thoracic epidural anesthesia (HTEA) blocks the afferent and efferent cardiac sympathetic nerve fibers and may affect atrial electrophysiologica ...
849.67 KB
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Electromechanical effects of th ...
Activation of the atrial renin–angiotensin system plays an important role in the pathophysiology of atrial fibrillation (AF). The pulmonary vein (PV ...
648.31 KB
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MGMT promoter methylation and t ...
Choroid plexus carcinoma (CPC) is a malignant tumor with a strong tendency to spread along the cerebrospinal fluid pathway. There is no standardized ...
348.35 KB
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Are we missing the mTOR target ...
Abnormalities in the PI3K/Akt/mTOR intracellular signalling pathway have been implicated in several forms of human cancer. The central component of ...
125.72 KB
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Detection of circulating tumor ...
Most assays to detect circulating tumor cells (CTCs) rely on EpCAM expression on tumor cells. Recently, our group reported that in contrast to other ...
610.66 KB
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The b2-adrenergic receptor and ...
In this study, b2-AR level was found to be up-regulated in MCF-7 cells overexpressing Her2 (MCF-7/ Her2). Correlation of b2-AR level with Her2 statu ...
644.96 KB
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Results of a phase II study of ...
Palliation is the primary goal in metastatic breast cancer (MBC), and safe, efficacious, new singleagent options are needed. Pemetrexed, an antifola ...
233.82 KB
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Polymorphisms of tumor necrosis ...
We conducted a meta-analysis to assess the association between tumor necrosis factor-alpha (TNFalpha) gene TNFA-308 (G[A), TNFA-238 (G[A), TNFA -85 ...
318.37 KB
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Joint effect of peroxisome prol ...
Peroxisome proliferator-activated receptor c (PPARc) has been linked with possible antineoplastic effects in colorectal carcinogenesis. However, dat ...
195.81 KB
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Cognitive function in postmenop ...
Endocrine therapy for breast cancer may affect cognition. The purpose of this study was to examine whether cognitive function improves after cessati ...
241.12 KB
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Centrosome-related genes, genet ...
Centrosome amplification has been detected in premalignant lesions and in situ tumors in the breast and in over 70%of invasive breast tumors, and ha ...
169.99 KB
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Young age, increased tumor prol ...
It is unclear if earlier onset (\40 years) and greater proliferative capacity confer an equally poor prognosis to endocrine-dependent and endocrine- ...
382.16 KB
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Mutation analysis of the SLX4/F ...
SLX4 coordinates three structure-specific endonucleases in the DNA damage response. One subtype of Fanconi anaemia, FA-P, has recently been attribut ...
349.93 KB
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Routine pathologic parameters c ...
OncotypeDXTM is an RT-PCR-based assay used to predict chemotherapy benefit in patients with estrogen receptor (ER) positive breast cancers. We were ...
450.68 KB
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Mothers’ pre-pregnancy BMI and ...
Previous studies have established that higher birthweight is associated with increased risk of breast cancer. However, the mechanisms underlying thi ...
179.51 KB
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The influence of removal of pri ...
Recent studies have shown that the detection of circulating tumor cells (CTC) pre and postoperatively in the peripheral blood of primary breast canc ...
306.43 KB
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The association of reproductive ...
Reproductive factors that influence breast cancer risk may also have an impact on survival, once the disease is diagnosed. In this study, 2,640 wome ...
198.26 KB
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Membrane localization of insuli ...
Recent studies have identified a role for insulin receptor substrate-2 (IRS-2) in promoting motility and metastasis in breast cancer. However, no pu ...
1.34 MB
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Traditional breast cancer risk ...
At least four major categories of invasive breast cancer have been reproducibly identified by gene expression profiling: luminal A, luminal B, HER2- ...
200.03 KB
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Different CHEK2 germline mutati ...
Germline mutations in BRCA1 were already linked to basal-like subtype of immunophenotypic molecular classification of breast cancer (BC). However, i ...
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