Intrathecal application of dono ...
Extramedullary relapses after allogeneic stem cell transplantation, especially within the central nervous system (CNS), are not only difficult to tr ...
Synergistic effect of bortezomi ...
The synergistic effect of proteasome inhibitor bortezomib and valproic acid (VPA), a histone deacetylase inhibitor, were investigated in this study. ...
The metalloprotease, NN-PF3 fro ...
NN-PF3 is a non-toxic, anticoagulant, highmolecular- mass (67.81 kDa) metalloprotease from Indian cobra (Naja naja) venom. In the present study, NN- ...
Possible prediction of underlyi ...
In some instances, because of the lack of mass formation and the absence of prominent lymph node enlargement, diagnosis of lymphoma-associated hemop ...
Risk factors for infection and ...
This study was performed to evaluate the impact of extended-spectrum β-lactamase (ESBL)-producing bacteremia on outcome in patients with hematologic ...
Second line chemotherapy in pat ...
Enteropathy-associated T cell lymphoma (EATL) is a rare disease with a dismal prognosis. Due to the low efficacy of chemotherapy and the poor perfor ...
Diagnostic role of initial rena ...
Objective Assessment of the first febrile urinary tract infection (UTI) in children has been the subject of debate for many years. Diagnosis of acut ...
Investigation of dose distribut ...
Objective In this study, radial dosimetric characterization for specific internal geometry of seed source was determined. In this study, the separat ...
Relationship between 18F-FDG up ...
Background Positron emission tomography (PET) imaging with 2-[18F]-fluoro-2-deoxy-D-glucose (18F-FDG) has a false-positive result in benign pulmonar ...
Attentional processing of infan ...
The mother–infant relationship has an important influence on maternal mental health and infant development. Evidence suggests that this relationship ...
Bio-socio-demographic factors a ...
Post-traumatic stress disorder (PTSD) is common among women. In the postpartum period, the prevalence is between 1% and 6%. The present study invest ...
Hematopoietic cytokines for car ...
influence cellular proliferation, differentiation, maturation, and lineage commitment in the bone marrow, include granulocyte colony-stimulating fac ...
NADPH oxidases in cardiovascula ...
NADPH oxidase family enzymes (or NOXs) are the major sources of reactive oxygen species (ROS) that are implicated in the pathophysiology of many ca ...
Diastolic dysfunction and arrhy ...
Transgenic (TG) Ca2?/calmodulin-dependent protein kinase II (CaMKII) dC mice develop systolic heart failure (HF). CaMKII regulates intracellular Ca2 ...
Distinct mechanisms for diastol ...
Chronic pressure-overload and diabetes mellitus are two frequent disorders affecting the heart. We aimed to characterize myocardial structural and f ...
Effect of sulfur dioxide precon ...
Sulfur dioxide has recently been found to be produced endogenously in the cardiovascular system and have important positive biological effects. Howe ...
CXCL12/CXCR4 signaling in malig ...
Chemokines are 8- to 12-kDa peptides that function as chemoattractant cytokines involved in cell activation, differentiation, and trafficking. Chemo ...
Genetic profile of astrocytic a ...
Low-grade diffuse gliomasWHOgrade II (diffuse astrocytoma, oligoastrocytoma, oligodendroglioma) are characterized by frequent IDH1/2 mutations ([80% ...
Indeterminacy in the WHO classi ...
The WHO classifications of tumors are the global standards of tumor diagnosis. In spite of the detailed descriptions of the histopathological featur ...
RERG (Ras-like, oestrogen-regul ...
Global gene expression profiling studies have classified breast cancer into a number of distinct biological and molecular classes with clinical rele ...
Amplification of ESR1 may predi ...
The estrogen receptor (ER) is the target of tamoxifen, but endocrine therapies do not benefit all patients with ER positive tumors. We therefore hyp ...
Mediator of DNA damage checkpoi ...
The mediator of DNA damage checkpoint protein 1 (MDC1) regulates cell cycle checkpoints and recruits repair proteins to sites of double-stranded DNA ...
DEAD box 1: a novel and indepen ...
Breast cancer is a heterogeneous disease characterized by diverse molecular signatures and a variable response to therapy. Clinical management of br ...
Uptake of 2-NBDG as a method to ...
This study quantifies uptake of a fluorescent glucose analog, (2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4- yl)amino)-2-deoxyglucose) (2-NBDG), in a large ...
The TGF-b/Smad pathway induces ...
Transforming growth factor-b (TGF-b) has opposing roles in breast cancer progression by acting as a tumor suppressor in the initial phase, but stimu ...