Markers of childhood lupus neph ...
Current treatment regimens for childhood lupus nephritis (LN) are associated with significant side-effects and toxicity in vulnerable phases of grow ...
Two-photon in vivo imaging of c ...
In vivo imaging of cells gives a glimpse into the world of biology in a natural setting unparalleled by any other venue. Two-photon imaging of fluor ...
Respiratory-chain deficiency pr ...
Renal manifestations of mitochondrial cytopathies have been described, but nephrotic syndrome with respiratory-chain disorders have been described e ...
Measurement of saliva tacrolimu ...
The aim of this study was to investigate whether a strong and clinically applicable correlation exists between saliva and whole-blood tacrolimus lev ...
En-bloc pediatric kidney transp ...
There is a continuing debate about the techniques of kidney transplantation from small donors because of the high vascular thromboses and ureteric l ...
First and second branchial arch ...
First and second branchial arch syndromes (BAS) manifest as combined tissue deficiencies and hypoplasias of the face, external ear, middle ear and ...
Antenatal imaging: does the pos ...
This review explores what is already understood about antenatal diagnosis of a variety of conditions, including Down syndrome, what progress has bee ...
Molecular ultrasound imaging an ...
US is a low-cost, real-time imaging modality that is the most used diagnostic tool in paediatric radiology. Reasons include the improved US image q ...
Value of postmortem thoracic CT ...
Background Studies have reported that thoracic CT may provide greater sensitivity compared with radiography in detection of pediatric rib fractures ...
Unexpected MRI findings in clin ...
Background In the setting of clinically suspected Legg- Calvé-Perthes (LCP) disease and negative/equivocal radiographs, contrast-enhanced MRI can be ...
Whole-body MR angiography: init ...
Radiological assessment of vasculopathy in children is typically undertaken with ultrasonography, echocardiography, conventional angiography, comput ...
US assessment of estrogen-respo ...
Background A mother’s circulating estrogen increases over the third trimester, producing physiological effects on her newborn that wane postnatally. ...
The nature of backbone monomers ...
The influence of the composition of soft contact lenses on the achievement of a significant increase in drug loading and control release capability w ...
p53 binds preferentially to gen ...
The human transcription factor TP53 is a pivotal roadblock against cancer. A key unresolved question is how the p53 protein selects its genomic bindi ...
The antagonism between MCT-1 an ...
Background: MCT-1 oncoprotein accelerates p53 protein degradation via a proteosome pathway. Synergistic promotion of the xenograft tumorigenicity has ...
The Human Glioma-Associated Onc ...
Sonic hedgehog (Shh) signaling is critically important for embryogenesis and other cellular processes in which GLI transcription factors mediate the ...
Osmoadaptation of Mammalian Cel ...
In mammals, the cells of the renal medulla are physiologically exposed to interstitial osmolalities several-fold higher that found in any other tissu ...
HLA Genes in Mayos Population f ...
HLA class I and class II alleles have been studied in 60 unrelated people belonging to Mayos ethnic group, which lives in the Mexican Pacific Sinaloa ...
Transcription Factor CHF1/Hey2 ...
We have previously found that overexpression of CHF1/Hey2 in the myocardium prevents the development of phenylephrine-induced hypertrophy. To identif ...
Advances on the Understanding o ...
Although Alzheimer’s disease (AD) was first discovered a century ago, we are still facing a lack of definitive diagnosis during the patient’s lifetim ...
Involvement of Nuclear Export i ...
The E6 protein from high-risk human papillomaviruses (HPVs) targets the p53 tumor suppressor for degradation by the proteasome pathway. This ability ...
Safety of a Virosomal Adjuvante ...
Children suffering from chronic disease are at increased risk for complications and mortality caused by influenza. Influenza can be most effectively ...
Assembly of the Asparagine- and ...
The proteins Ure2, Sup35 and Rnq1 from the baker’s yeast have infectious properties, termed prions, at the origin of heritable and transmissible phen ...
One Decade Later: What has Gene ...
The many diverse functions executed by the central nervous system (CNS) are mirrored in the diverse shapes, connections, and firing patterns of its i ...
How Drosophila melanogaster For ...
A strictly determined number of external sensory organs, macrochaetes, acting as mechanoreceptors, are orderly located on drosophila head and body. T ...