Class A scavenger receptor attenuates myocardial infar ...
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Class A scavenger receptor atte ...
Classically (M1) and alternatively (M2) activated macrophage subsets play differential roles in left ventricular remodeling after myocardial infarct ...
1.45 MB
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Rhabdoid glioblastoma in a chil ...
Rhabdoid glioblastoma is a rare type of glioblastoma characterized by cells resembling rhabdomyoblasts. Several reports have identified its aggressi ...
دانلود 1
580.77 KB
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The ErbB3 binding protein EBP1 ...
The ErbB2/3 heterodimer plays a critical role in breast cancer progression and in the development of endocrine resistance. EBP1, an ErbB3 binding pr ...
461.14 KB
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MPA-induced gene expression and ...
Over the past several years, we have been interested in understanding the mechanisms by which mammary carcinomas acquire hormone independence. We d ...
1.20 MB
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Time to move forward from ‘‘fir ...
For clinicians, it has been clear for many years that breast cancer patients with the same clinical and pathological characteristics can have divers ...
دانلود 1
120.18 KB
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International distribution and ...
The c.156_157insAlu BRCA2 mutation has so far only been reported in hereditary breast/ovarian cancer (HBOC) families of Portuguese origin. Since thi ...
332.17 KB
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Insulin like growth factor bind ...
Previously, we have shown that insulin-like growth factor binding protein-7 (IGFBP-7) expression is inversely correlated with disease progression in ...
750.15 KB
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Declining melatonin levels and ...
Serum melatonin (MLT) levels have been reported to diminish significantly by the 5th and 6th decades of life as the incidence of breast cancer incre ...
388.37 KB
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Topoisomerase II alpha protein ...
Overexpression of topoisomerase II protein (topo 2a) is postulated to be more closely associated with responsiveness to anthracycline-containing che ...
355.08 KB
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Anti-tissue factor short hairpi ...
In breast cancer, there is a correlation between tissue factor (TF) expression, angiogenesis and disease progression. TF stimulates tumour angiogene ...
627.40 KB
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Evidence on the association bet ...
Several molecular epidemiological studies were conducted in recent years to evaluate the association between NQO1 Pro187Ser polymorphism and breast ...
260.42 KB
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Anastrozole and letrozole: an i ...
Previous studies have demonstrated that both anastrozole and letrozole are well tolerated. Letrozole suppresses estrogen to a greater degree than an ...
225.04 KB
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G-protein-coupled estrogen rece ...
Recently, we have shown that the new G-protein- coupled estrogen receptor GPR30 plays an important role in the development of tamoxifen resistance i ...
625.10 KB
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Possible risk modifications in ...
Manganese superoxide dismutase (MnSOD) has been identified as an important scavenger of reactive oxygen species (ROS), which can cause oxidative str ...
572.60 KB
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Sentinel node micrometastases i ...
Sentinel node biopsy (SNB) for axillary staging in breast cancer allows the application of more extensive pathologic examination techniques. Microme ...
821.26 KB
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RAD51 135G>C polymorphism an ...
Mutations in RAD51 gene are believed to be associated with elevated breast cancer risk. However, several case–control studies focusing on the associ ...
298.77 KB
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Improvement in self-reported ph ...
Physical health-related quality of life scores have been, inconsistently, associated with breast cancer prognosis. This analysis examined whether ch ...
195.79 KB
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Risk of aggressive breast cance ...
The high morbidity and aggressive behavior of breast cancer are associated with genetic variations. Single nucleotide polymorphisms (SNPs) in many g ...
235.29 KB
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Polymorphic variants in TSC1 an ...
TSC1 acts coordinately with TSC2 in a complex to inhibit mTOR, an emerging therapeutic target and known promoter of cell growth and cell cycle progr ...
252.01 KB
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Glutathione S-transferase P1 Il ...
Glutathione S-transferase P1 (GSTP1) is involved in a wide range of detoxifying reactions. Any alteration in the structure, function, or expression ...
271.98 KB
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In situ detection of HER2:HER2 ...
HER2 overexpression/amplification is linked with poor prognosis in early breast cancer. Co-expression of HER2 and HER3 is associated with endocrine ...
408.07 KB
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Absenteeism and short-term disa ...
Few data exist related to the impact of breast cancer on work absenteeism and short-term disability. This retrospective study estimated the extent a ...
277.08 KB
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FOXA1 is an independent prognos ...
Forkhead box protein A1 (FOXA1) is a ‘‘pioneer factor’’ that plays a role in controlling nearly 50% of estrogen receptor target genes. FOXA1 express ...
434.05 KB
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IL-15 and IL-2 increase Cetuxim ...
Triple negative breast cancer (TNBC) patients are not likely to benefit from anti-estrogen or anti-HER2 therapy and this phenotype is associated wit ...
656.49 KB
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Gene expression profiling of br ...
Microtubule-targeting agents, including taxanes (Tax) and ixabepilone (Ixa), are important components of modern breast cancer chemotherapy regimens, ...
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