Cause of Chirality Consensus
Clinical Utility of Microarrays ...
Microarray-based clinical tests have become powerful tools in the diagnosis and treatment of diseases. In contrast to traditional DNA-based tests tha ...
Mass Spectrometry-Based Approac ...
Mass spectrometry has served as a major tool for the discipline of proteomics to catalogue proteins in an unprecedented scale. With chemical and meta ...
Cause and Consequences of Genet ...
Both genetic and epigenetic changes contribute to development of human cancer. Oncogenomics has primarily focused on understanding the genetic basis ...
Genetic Variation and Atheroscl ...
A family history of atherosclerosis is independently associated with an increased incidence of cardiovascular events. The genetic factors underlying ...
Oncogenomic Approaches in Explo ...
Cancer is caused by the spatial and temporal accumulation of alterations in the genome of a given cell. This leads to the deregulation of key signall ...
How Drosophila melanogaster For ...
A strictly determined number of external sensory organs, macrochaetes, acting as mechanoreceptors, are orderly located on drosophila head and body. T ...
Gene Polymorphisms and Pharmaco ...
Rheumatoid arthritis (RA) is a systemic, chronic and inflammatory disease of unknown etiology with genetic predisposition. The advent of new biologic ...
Drosophila Lethal Giant Larvae ...
Drosophila lethal giant larvae (lgl) is a tumour suppressor gene whose function in establishing apical-basal cell polarity as well as in exerting pro ...
Genetics and Molecular Biology ...
Tuberous Sclerosis Complex is a multisystem disorder exhibiting a wide range of manifestations characterized by tumour-like lesions called hamartomas ...
Periostin as a Heterofunctional ...
Periostin (Postn) is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesi ...
Salivary Genomics, Transcriptom ...
There is an increasingly growing interest world-wide for the genomics, transcriptomics and proteomics of saliva and the oral cavity, since they provi ...
Application of TILLING and EcoT ...
With the fairly recent advent of inexpensive, rapid sequencing technologies that continue to improve sequencing efficiency and accuracy, many species ...
Alternative Splicing and Tumor ...
Alternative splicing is a key molecular mechanism for increasing the functional diversity of the eukaryotic proteomes. A large body of experimental d ...
Analysis of NCL Proteins from a ...
The Neuronal Ceroid Lipofuscinoses (NCLs) are the most common group of neurodegenerative disorders of childhood. While mutations in eight different g ...
Molecular Mechanisms of Inherit ...
Inherited arrhythmias and conduction system diseases are known causes of sudden cardiac death and are responsible for significant mortality and morbi ...
Recent Advances in the Characte ...
Human resistance to infection by schistosomes is associated to a strong Th2 immune. However a persistent Th2 response can cause severe kidney and liv ...
Nutrigenomic Analysis of Diet-G ...
Recent advances in molecular biology combined with the wealth of information generated by the Human Genome Project have fostered the emergence of nut ...
Toxicogenomics to Improve Compr ...
Engineered nanomaterials are commonly defined as materials with at least one dimension of 100 nanometers or less. Such materials typically possess na ...
A Systematic Review of Meta-Ana ...
Background. Individual variations in gastric cancer risk have been associated in the last decade with specific variant alleles of different genes tha ...
Multiple Hsp70 Isoforms in the ...
Hsp70 molecular chaperones play a variety of functions in every organism, cell type and organelle, and their activities have been implicated in a num ...
Regulation of the Endoplasmic R ...
Calcium is a ubiquitous second messenger and is involved in virtually all cellular functions. Cellular events being regulated by calcium include gene ...
Computational Approaches for Pr ...
A central focus of cancer genetics is the study of mutations that are causally implicated in tumorigenesis. Although missense variants are commonly i ...
Cause of Chirality Consensus
Biological macromolecules, proteins and nucleic acids are composed exclusively of chirally pure monomers. The chirality consensus appears vital for l ...
S100A8 and S100A9 Overexpressio ...
S100 protein A8 and A9 naturally form a stable heterocomplex. Recently, we have proved that S100A9 overexpression in various adenocarcinomas is assoc ...
Ghrelin Regulates Insulin Relea ...
Insulin release from pancreatic islet ..-cells is stimulated by glucose. Glucose-induced insulin release is potentiated or suppressed by hormones and ...