A Survey of Chloroplast Protein ...
Protein phosphorylation is a major mode of regulation of metabolism, gene expression and cell architecture. In chloroplasts, reversible phosphorylati ...
Pan-Vertebrate Toll-Like Recept ...
Human toll-like receptors (TLRs) recognize pathogen-associated molecular patterns (PAMPs) to raise innate immune responses. The human TLR family was ...
The Genomics of Colorectal Canc ...
The concept of the adenoma-carcinoma sequence, as first espoused by Morson et al. whereby the development of colorectal cancer is dependent on a step ...
Analysis of the Fragile X Trinu ...
Fragile X Syndrome (FXS) is associated with an unstable CGG repeat sequence in the 5’ untranslated region in the first exon of the FMR1 gene which re ...
Gene therapy: Regulations, ethi ...
Gene therapy is a new and promising approach which opens a new door to the treatment of human diseases. By direct transfer of genetic materials to t ...
Genomic Organization and Contro ...
Grb7 and their related family members Grb10 and Grb14 are adaptor proteins, which participate in the functionality of multiple signal transduction pa ...
Comprehensive Resources for Tom ...
Tomato (Solanum lycopersicum L., Solanaceae) is an excellent model plant for genomic research of solanaceous plants, as well as for studying the deve ...
NBS1 Heterozygosity and Cancer ...
Biallelic mutations in the NBS1 gene are responsible for the Nijmegen breakage syndrome (NBS), a rare autosomal recessive disorder characterized by c ...
Modeling the Genetic Control of ...
The progression of HIV disease has been markedly slowed by the use of highly active antiretroviral therapy (HAART). However, substantial genetic vari ...
Haploinsufficiency of DNA Damag ...
Genomic disorders are a clinically diverse group of conditions caused by gain, loss or re-orientation of a genomic region containing dosage-sensitive ...
On the Epistemological Crisis i ...
There is an epistemological crisis in genomics. At issue is what constitutes scientific knowledge in genomic science, or systems biology in general. ...
Understanding Genetic Factors i ...
Idiopathic scoliosis (AIS) is the most common pediatric spinal deformity, affecting ~3% of children worldwide. AIS significantly impacts national hea ...
Meta Analysis of Gene Expressio ...
Since the second half of the 1990s, a large number of genome-wide analyses have been described that study gene expression at the transcript level. To ...
Molecular Cytogenetics and Cyto ...
Molecular cytogenetics is a promising field of biomedical research that has recently revolutionized our thinking on genome structure and behavior. Th ...
Episcopic 3D Imaging Methods: T ...
This work aims at describing episcopic 3D imaging methods and at discussing how these methods can contribute to researching the genetic mechanisms dr ...
Systems Behavior: Of Male Court ...
Male courtship in fruit flies is regulated by the same major regulatory genes that also determine general sexual differentiation of the animal. Elabo ...
Post-Translational Control of S ...
Sp-family transcription factors are widely expressed in human tissues and involved in the regulation of many cellular processes and response to cellu ...
Functional and Clinical Evidenc ...
We searched for potential suppressors of tumor metastasis by identifying the genes that are frequently down-regulated in hepatocellular carcinomas ( ...
MicroRNA and Cancer: Tiny Molec ...
Cancer is currently a major public health problem and, as such, emerging research is making significant progress in identifying major players in its ...
The Potential Role of Pharmacog ...
Although notable progress has been made in the treatment of non-small-cell lung cancer (NSCLC) in recent years, this disease is still associated with ...
Genome Analysis of Food Grade L ...
Whole-genome sequencing has revolutionized and accelerated scientific research that aims to study the genetics, biochemistry and molecular biology of ...
Plant Spliceosomal Introns: Not ...
Spliceosomal introns in higher eukaryotes are present in a high percentage of protein coding genes and represent a high proportion of transcribed nuc ...
Computational Challenges of Per ...
It is widely predicted that cost and efficiency gains in sequencing will usher in an era of personal genomics and personalized, predictive, preventiv ...
Can Systems Biology Understand ...
Cancer is thought to be caused by a sequence of multiple genetic and epigenetic alterations which occur in one or more of the genes controlling cell ...
Genetic and Molecular Basis of ...
A systematic study has been conducted of all available reports in PubMed and OMIM (Online Mendelian Inheritance in Man) to examine the genetic and mo ...