The Challenges of Providing Pal ...
Palliative care seems the right approach to dementia, except that it suggests a dichotomy between cure and care. As in cancer care, supportive care ...
Optimal Management of Bone Meta ...
The biological basis of the selective outgrowth of disseminated prostate cancer cells within the hematopoietic bone microenvironment remains a compe ...
Second Primary Tumors in Patien ...
This is a review on second primary tumors in patients with head and neck cancer. These patients have a high risk of developing other cancers simulta ...
Palliative Medicine: Barriers a ...
The development of palliative care in China is vital to the care of its aging population and associated increase in cancer incidence. There are phys ...
Variant Forms of Bladder Cancer ...
Variant forms of bladder cancer are non-urothelial neoplasms or urothelial carcinomas mixed with other histologies. Compared to pure urothelial carc ...
Changing the Perspective: Curre ...
Functional outcome and quality of life have become frequent outcome measures in head and neck cancer (HNC) clinical trials. Many thoroughly validate ...
The Evolving Role of Targeted T ...
Many of the leading developments in management of non-small cell lung cancer (NSCLC) have been provided by the integration of specific targeted ther ...
Predictive and Prognostic Marke ...
Colorectal cancer (CRC) has a complex pathogenesis involving multiple sequential steps with accumulation of genetic alterations including mutations, ...
Quality of Care in Head and Nec ...
Improving the quality of health care has become a national priority, as indicated by the establishment of multiple federal initiatives and by the ac ...
The Optimal Chemotherapy for St ...
Nearly one third of non–small cell lung cancer (NSCLC) patients at diagnosis have stage III disease. Concurrent chemoradiation has emerged as the st ...
Current Treatment Options for P ...
Pancreas cancer is a significant cause of cancer mortality; therefore, the development of early diagnostic strategies and effective treatment is ess ...
Sipuleucel-T: Prototype for Dev ...
Prostate cancer immunotherapy officially debuted with the recent FDA approval of Sipuleucel-T. The novel trend of cancer immunotherapy relies on the ...
Medical Treatment of Mesothelio ...
In the present report, we review the current standard and investigational treatments of malignant pleural mesothelioma (MPM). Several studies have r ...
Hepatocellular Carcinoma: Preve ...
Hepatocellular carcinoma (HCC) is an aggressive malignancy of the liver and occurs most often in the setting of chronic liver disease. The most comm ...
Development of Second-Generatio ...
The vascular endothelial growth factor (VEGF) signaling pathway appears to be the dominant pathway involved in tumor angiogenesis, providing a ratio ...
Ramucirumab (IMC-1121B): Monocl ...
Angiogenesis, a well-recognized characteristic of malignancy, has been exploited more than any other pathway targeted by biologic anti-neoplastic th ...
Malignant Pleural Mesothelioma
Malignant pleural mesothelioma (MPM) is a relatively rare thoracic malignancy accounting for about 2000–3000 new cases per year. This cancer has bee ...
Update on Treatment Advances in ...
Concurrent radiation therapy and chemotherapy is the primary treatment for patients with squamous cell tumors of the anal canal, and is also employe ...
Abiraterone Acetate, A Novel Ad ...
The androgen receptor remains the key player in patients with castration-resistant prostate cancer (CRPC). Available agents capable of blocking earl ...
Curable Metastatic Colorectal C ...
In the United States and Europe, colorectal cancer (CRC) is the third most common malignancy and the second leading cause of cancer-related death fo ...
Commentary: Implications of Can ...
In an increasing number of settings it is appropriate to consider cancer as a very serious but also a chronic disease process. This commentary discu ...
Update: Modern Approaches to th ...
The optimal treatment strategy for esophageal cancer continues to be a topic of debate. Improvements in chemotherapy drugs, surgical techniques, and ...
Advances in Epigenetics and Epi ...
In the post-genomic era, epigenetic factors— literally those that are “over” or “above” genetic ones and responsible for controlling the expression ...
Pharmacogenomics and Multiple S ...
Notwithstanding the availability of diseasemodifying treatments including interferon-β, glatiramer acetate, and natalizumab, a considerable proporti ...
Role of Cerebrospinal Fluid and ...
Biomarkers are one type of laboratory testing being developed in response to the therapeutic imperative for diseases that cause cognitive impairment ...