The Radiologically Isolated Syn ...
The advent and wide use of magnetic resonance brain imaging has led to in the unexpected detection of lesions that appear typical of multiple sclero ...
Gait Abnormalities in Multiple ...
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system characterized by episodic decline in various neurologic functions. ...
Fingolimod for Multiple Scleros ...
The oral sphingosine 1-phosphate receptor (S1PR) modulator fingolimod functionally antagonizes S1PR hereby blocking lymphocyte egress from secondary ...
The Pathophysiologic Basis of S ...
The symptoms of narcolepsy can occur during the course of other neurologic conditions (ie, symptomatic narcolepsy). Inherited disorders, tumors, and ...
Biofeedback and Epilepsy
Biofeedback is a noninvasive behavioral treatment that enables a patient to gain volitional control over a physiological process. As a treatment for ...
The Sleep Manifestations of Fro ...
Frontal lobe seizures have a tendency to occur from sleep, and in some cases occur exclusively (or almost exclusively) from sleep; these individuals ...
Hormonal Therapy for Epilepsy
In 2011, there are greater than 20 antiepileptic medications available. These medications work by modulating neuronal excitability. Reproductive hor ...
Epilepsy and Autism: Neurodevel ...
Epilepsy and autism coexist in up to 20% of children with either disorder. Current studies suggest that a frequent co-occurring condition in epileps ...
Advances in MRI Assessment of G ...
Bevacizumab is thought to normalize tumor vasculature and restore the blood–brain barrier, decreasing enhancement and peritumoral edema. Conventiona ...
Newly Postulated Neurodevelopme ...
Recent animal and human studies have raised concern that exposure to anesthetic agents in children may cause neuronal damage and be associated with ...
Antiepileptic Drugs and Neurode ...
In utero exposure to some antiepileptic drugs (AEDs) is associated with an increased risk of impaired cognitive development. Specifically, valproate ...
Current State of Our Knowledge ...
The overall incidence of brain tumors for benign and malignant tumors combined is 18.71 per 100,000 person-years; 11.52 per 100,000 person-years for ...
Rescue Therapies for Seizures
Most medical therapies for epilepsy consist of daily (or multiple-daily) dose, fixed-schedule, pharmacologic oral agents. Despite adherence, many pa ...
Adult Primary Intradural Spinal ...
Primary spinal cord tumors constitute 2% to 4% of all central nervous system neoplasms and are characterized based on their location as intramedulla ...
Prognosis of Intractable Epilep ...
Until recently, very little data existed on longterm seizure prognosis of patients with intractable epilepsy. We review recent work that assessed se ...
Neurosurgery for Brain Tumors: ...
Advances in diagnostic imaging modalities and improved access to specialty care have led directly to an increased diagnosis of both metastatic and p ...
Alternative Surgical Approaches ...
The mainstay of epilepsy surgery is the resection of a presumed seizure focus or disruption of seizure propagation pathways. These approaches cannot ...
Patterns of Progression in Mali ...
Antiangiogenic treatment has recently become an integral part of modern cancer therapy targeting the vasculature of numerous aggressive malignancies ...
Molecular Genetics of Neuronal ...
Cortical malformations associated with defects in neuronal migration result in severe developmental consequences including intractable epilepsy and ...
An Update on Psychogenic Moveme ...
Psychogenic movement disorders (PMD) and other conversion disorders (CD) with apparent neurologic signs (neurologic CD) plague patients and perplex ...
NMDA Receptor Antibody Encephal ...
N-methyl-D-aspartate receptor (NMDAR) antibody encephalitis is a recently described immunotherapyresponsive panencephalitis with characteristic feat ...
Differential Diagnosis of Chore ...
Chorea is a common movement disorder that can be caused by a large variety of structural, neurochemical (including pharmacologic), or metabolic dist ...
Genomic Profiles of Glioma
Recent large-scale genomic profiling studies of glioma have yielded a proliferation of candidate subclasses, biomarkers and therapeutic targets for ...
Gastrointestinal Features of Pa ...
Gastrointestinal (GI) symptoms are among the most common nonmotor manifestations of Parkinson’s disease (PD), and they have many important ramificat ...
Molecular Mechanisms of PINK1-R ...
PINK1 is a mitochondrially targeted kinase that has been linked to a rare monogenic form of Parkinson’s disease (PD), a common neurodegenerative dis ...