Impact of Hypertension on Stroke
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Genetics of Rhinosinusitis
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Impact of Hypertension on Strok ...
Hypertension is the single most important risk factor for all types of stroke: ischemic stroke, intracerebral hemorrhage, and aneurysmal subarachnoi ...
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MicroRNAs in Cardiometabolic Di ...
Defects in homeostatic regulation of cholesterol and fatty acids are associated with major cardiometabolic risk factors that are prevalent in type 2 ...
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Evolving Concepts of the Role o ...
High-density lipoprotein (HDL) is classified as a negative risk factor due to the inverse relationship between elevated levels of HDL cholesterol an ...
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Prediction of Stroke Risk in At ...
Atrial fibrillation (AF) is a large public health problem that affects about 1% of the population in the United States. It confers an increased risk ...
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Genetic Mechanisms Mediating At ...
Recent genome-wide association studies have demonstrated that common genetic variants in a region of chromosome 9p21 confer risk of coronary artery ...
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Severe Asthma with Fungal Sensi ...
A new phenotype of asthma has been described recently, namely severe asthma with fungal sensitization (SAFS). SAFS can be conceptualized as a contin ...
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Importance of Allergy in Asthma ...
There has been a global epidemic of asthma during the past half-century. More recently, the prevalence has leveled off or declined in many Western c ...
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Basophils and Autoreactive IgE ...
Systemic lupus erythematosus (SLE) is a heterogeneous disease that can affect multiple organs. A hallmark of this disease, as is the case for other ...
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Role of Allergen Sensitization ...
There is a common perception among physicians and patients that allergic diseases are not relevant in older adults. There is also recognition that i ...
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Role of Sensitization to Mammal ...
Serum albumin (SA) constitutes an intriguing puzzle that is involved in allergic sensitizations from different sources and induces different clinica ...
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Impact of Environmental Control ...
Exposure to allergens early in life can lead to sensitization and the development of childhood asthma. It is thought that increased exposure with th ...
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Recent Insights into the Pathob ...
Primary immunodeficiencies are a heterogeneous group of genetically inherited diseases affecting the innate and adaptive immune systems that confer ...
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Breastfeeding and Otitis Media: ...
Human milk provides infants with antimicrobial, anti-inflammatory, and immunomodulatory agents that contribute to optimal immune system function. Th ...
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The Emerging Role of Interleuki ...
The autoinflammatory syndromes are a group of multisystem disorders characterized by recurrent episodes of fever and systemic inflammation affecting ...
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The New Era of C1-Esterase Inhi ...
Hereditary angioedema (HAE) is an autosomal dominant disorder clinically characterized by recurrent episodes of angioedema. Until late-2008, HAE the ...
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Effectiveness of Air Filters an ...
Air filtration is frequently recommended as a component of environmental control measures for patients with allergic respiratory disease. Residentia ...
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Tourette syndrome (TS) bears a ...
Background Deep brain stimulation (DBS) is a commonly performed surgical technique for the treatment of movement disorders, and recent surgical tria ...
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The Potential Role of Interleuk ...
Asthma has long been characterized as a disease of dysregulated T-helper type 2 immune responses to environmental allergens. Clinical studies sugge ...
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Guidelines 2.0: Do No Net Harm— ...
Decisions are like double-edged swords: they always come with benefits and downsides. That is, any decision in life bears desirable and undesirable ...
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Monoclonal Antibodies for the T ...
Patients with severe asthma have a significant unmet need with persistent symptoms and/or frequent exacerbations despite treatment with high-dose st ...
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Mechanisms of IgE Inflammation
The prevalence of diseases such as allergic asthma and rhinitis continues to increase in the United States, affecting millions of people. It is well ...
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Immunologic Similarities betwee ...
Food allergies are an important medical problem in Westernized countries. Allergy to peanuts is a dramatic example of a food allergy that tends to b ...
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Quality of Life in Patients wit ...
Health-related quality of life (HRQoL) is a domain of quality-of-life assessment that is influenced by the individual’s perception of his or her hea ...
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The History of IgE: From Discov ...
The discovery of IgE and the role of IgEmediated inflammation gave clinical allergy a scientific backbone, and as a result, the reputation of the sp ...
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Genetics of Rhinosinusitis
Suggestion for a potential genetic basis to chronic rhinosinusitis (CRS) is afforded by degree of inheritability suggested from family and twin stud ...
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