Current Use of Botulinum A Toxi ...
Overactive bladder (OAB), which is refractory to oral medications, is a challenging condition. Patients with refractory idiopathic OAB often have se ...
Genetic Testing for Early Detec ...
Coronary heart disease (CHD) often presents suddenly with little warning. Traditional risk factors are inadequate to identify the asymptomatic high- ...
The High-Risk Plaque Initiative ...
The High-Risk Plaque (HRP) Initiative is a research and development effort to advance the understanding, recognition, and management of asymptomatic ...
Optimal Therapy in Hypertensive ...
Diabetes and its micro- and macrovascular complications represent a worldwide epidemic that will place an enormous financial burden on poorer countr ...
Utility of Atherosclerosis Imag ...
Decreased level of high density-lipoprotein cholesterol (HDL-C) is a rigorous predictor for future cardiovascular events. Much effort is being made ...
Developmental Mechanisms Involv ...
The common belief that signs of atherosclerosis and cardiovascular disease (CVD) are clinically relevant only during adult and elderly age is gradua ...
Experimental Models for the Inv ...
Reduction of low-density lipoprotein cholesterol by statin therapy has only modestly decreased coronary heart disease (CHD)-associated mortality in ...
The Role of Matrix Metalloprote ...
The matrix metalloproteinase (MMP) family of enzymes is involved in arterial wall extracellular matrix degradation and remodeling. The latter activit ...
Role of Hepatic Lipase and Endo ...
Reverse cholesterol transport (RCT) constitutes a key part of the atheroprotective properties of high-density lipoproteins (HDL). Hepatic lipase (HL ...
The Role of C-Reactive Protein ...
Much controversy surrounds the use of highsensitivity C-reactive protein (hs-CRP) as a marker of cardiovascular (CV) risk. Although data regarding t ...
Lecithin Cholesterol Acyltransf ...
Lecithin cholesterol acyl transferase (LCAT) is a plasma enzyme that esterifies cholesterol and raises highdensity lipoprotein cholesterol, but its ...
The Role of Beta-Blockers as Fi ...
National and international guidelines still recommend â-blockers (BBs) as first-line agents in uncomplicated prevention of hypertension. However, it ...
Detection of Atrial Fibrillatio ...
Identifying atrial fibrillation (AF) as the cause of stroke is important because it may trigger a change from therapy with antiplatelet agents to pr ...
Role of Phospholipid Transfer P ...
Reverse cholesterol transport (RCT) describes the process whereby cholesterol in peripheral tissues is transported to the liver where it is ultimate ...
Obstructive Sleep Apnea and the ...
Obstructive sleep apnea (OSA) is a common disorder with major neurocognitive and cardiovascular sequelae. It is estimated that more than one quarter ...
Prevention of Stroke Following ...
Transient ischemic attacks (TIAs) are common neurologic events characterized by stroke-like symptoms that completely resolve. They were previously t ...
Update on HDL Receptors and Cel ...
Efflux is central to maintenance of tissue and whole body cholesterol homeostasis. The discovery of cell surface receptors that bind high-density li ...
The Role of Lipoprotein-Associa ...
Lipoprotein-associated phospholipase A2 (Lp- PLA2) is an enzyme that generates inflammatory mediators within atherosclerotic plaques. In epidemiolog ...
Current Management of Symptomat ...
Intracranial arterial stenosis (IAS) is the cause of about 10% of all ischemic strokes in the United States, but may account for about 40% of stroke ...
Genome-Wide Association Studies ...
Cardiovascular disease remains the major cause of worldwide morbidity and mortality. Its pathophysiology is complex and multifactorial. Because the ...
Antithrombotic Management for T ...
The new definition and risk stratification for transient ischemic attack (TIA) have clear implications for the urgency of evaluation and treatment. ...
Genetics of Redox Systems and T ...
As atherosclerosis is still one of the major causes of death in Western populations, it is important to identify those individuals who are at increa ...
Vasculotoxic Effects of Insulin ...
As a result of ambiguous results from several recent trials in diabetes, scrutiny has focused on the potential effects of insulin and its role in at ...
Blood Lipids and Stroke: What M ...
Statin therapy has became the most important advance in stroke prevention since the introduction of aspirin and blood pressure–lowering therapies. O ...
Atherosclerosis: An Epigenetic ...
Increasing evidence points to dietary lipids and their derivates as dynamic modulators of pro- or anti-inflammatory gene expression pathways via the ...