Prevalence of patient-reported ...
The aim of this study is to describe the comorbidity profile in patients with early and established psoriatic arthritis (PsA). Patients with PsA wer ...
The role of ultrasound in rheum ...
The skin and nails are commonly involved in rheumatic conditions, both by the primary disease and/or long-term immunosuppressive treatments. These s ...
An independent review of NCCAM- ...
To promote an independent and critical evaluation of 11 randomised clinical trials (RCTs) of chiropractic funded by the National Centre for Compleme ...
Polymyositis associated with hy ...
Studies confirming a possible relationship of polymyositis within thyroid dysfunction, either hypothyroidism or hyperthyroidism, are hardly availabl ...
Management of rheumatoid arthri ...
Given the recent availability of novel biologic agents for the treatment of rheumatoid arthritis (RA), the Hong Kong Society of Rheumatology has dev ...
An overview of commonly used ra ...
Despite the advent of magnetic resonance imaging and musculoskeletal ultrasound, the plain radiographs of the hands and feet remain an important too ...
Evaluation of current therapeut ...
Behçet’s disease (BD) is a chronic relapsing vasculitis with multifunctional pathogenesis. The mucocutaneous and ocular lesions are the commonest ma ...
The association of Raynaud’s sy ...
Rheumatoid arthritis (RA) has traditionally been included among the diseases associated with Raynaud’s syndrome (RS). The prevalence of RS in patien ...
Animal Models of Osteonecrosis
Osteonecrosis is an uncommon but significant musculoskeletal disease characterized by focal areas of dead bone that often fail to heal even with int ...
Cysteine Cathepsins: Markers an ...
There is now growing evidence that lung cysteine cathepsins take part in several biological processes and pulmonary homeostasis, although their exac ...
Ionizing Radiation and Bone Los ...
Damage to normal, nontumor bone tissue following therapeutic irradiation increases the risk of fracture among cancer patients. For example, women tr ...
Cysteine Protease Cathepsins in ...
Extracellular matrix remodeling is an important mechanism in the initiation and progression of cardiovascular diseases. Cysteine protease cathepsins ...
Osteoradionecrosis of the Jaws
Osteoradionecrosis (ORN) is one of the most serious oral complications of head and neck cancer treatment with radiotherapy. There is bone tissue nec ...
Cathepsins S, L, and K and Thei ...
Members of the cysteine protease cathepsin family play an important part in human pathophysiology. Among those, Cathepsin K has a major role in enzy ...
Bisphosphonates and Osteonecros ...
The beneficial effects of the nitrogen-containing bisphosphonate drugs have been clearly defined, especially for the treatment for osteoporosis, met ...
The Emerging Relevance of the C ...
Cathepsin S is a lysosomal cysteine protease that has been shown to play a key role in MHC class II antigen presentation. Consequently, it has been ...
Pitfalls to Avoid and Advanceme ...
The optimal treatment for osteonecrosis of the hip is contingent on early and accurate diagnosis. Magnetic resonance imaging (MRI) has become the re ...
Cathepsin L in Normal and Patho ...
Cathepsin L is a ubiquitous lysosomal cysteine endopeptidase that is mainly involved in the metabolic turnover of intracellular proteins. However, i ...
Thyroid Cathepsin K: Roles in P ...
The human genome encodes 11 cysteine cathepsins belonging to the papain-like family of cysteine peptidases that are known predominantly as endo-lyso ...
Osteonecrosis of the Hip in Adu ...
Atraumatic osteonecrosis in adults most commonly presents in the hip. The specific etiology and pathogenesis is often uncertain, and we will review ...
Cysteine Cathepsins and the Ske ...
Cysteine cathepsins are lysosomal proteases with housekeeping as well as tissue-specific functions. One of their specialized functions includes the ...
Childhood Femoral Head Osteonec ...
Femoral head osteonecrosis (FHO) is potentially a devastating condition of the hip joint that can affect children and adults. The most serious outco ...
Cutting Edge Issues in Rheumati ...
Although the incidence of acute rheumatic fever and rheumatic heart disease has decreased significantly in regions of the world where antibiotics ar ...
Hydroxychloroquine: From Malari ...
Quinine was first recognized as a potent antimalarial agent hundreds of years ago. Since then, the beneficial effects of quinine and its more advanc ...
The Etiology of Paraneoplastic ...
Although they may sometimes appear similar, paraneoplastic autoimmunity has a unique pathogenesis, different from the classical autoimmune diseases ...