Genetic Interference: Don’t Sta ...
Meiosis is a dynamic process during which chromosomes undergo condensation, pairing, crossing-over and disjunction. Stringent regulation of the distr ...
DNA Transposons: Nature and App ...
Repeated DNA makes up a large fraction of a typical mammalian genome, and some repetitive elements are able to move within the genome (transposons an ...
Indispensable Roles of Plastids ...
The plastid is an organelle vital to all photosynthetic and some non-photosynthetic eukaryotes. In the model plant Arabidopsis thaliana, a number of ...
Functional Genomics of Brain Ag ...
Pivotal brain functions, such as neurotransmission, cognition, and memory, decline with advancing age and, especially, in neurodegenerative condition ...
Discovering Tumor Suppressor Ge ...
Classical tumor suppressor gene discovery has largely involved linkage analysis and loss-of-heterozygosity (LOH) screens, followed by detailed mappin ...
DNA Instability at Chromosomal ...
Human chromosomal fragile sites are specific genomic regions which exhibit gaps or breaks on metaphase chromosomes following conditions of partial re ...
Investigation of Molecular Mech ...
Recent advances into the understanding of molecular mechanism of chronic pain have been largely developed through the use of genetic manipulations. T ...
Therapeutics Based on microRNA: ...
Hepatocellular carcinoma (HCC) is a serious public health hazard. Polygenes involvement, accumulation of genetic and epigenetic changes and immune re ...
Genetics of Interleukin 1 Recep ...
Interleukin 1 receptor-like 1 (IL1RL1) is gaining in recognition due to its involvement in immune/inflammatory disorders. Well-designed animal studie ...
Improvement of Anti-Tumor DNA V ...
DNA vaccine encoding tumor associated antigens (TAAs) is an attractive strategy for tumor vaccine development. But its efficacy to induce efficient a ...
Glioma oncoprotein Bcl2L12 inhi ...
Glioblastoma multiforme (GBM) is a lethal brain tumor characterized by intense apoptosis resistance and extensive necrosis. Bcl2L12 (for Bcl2-like 12 ...
Retinoic Acid Induced 1, RAI1: ...
Genomic structural changes, such as gene Copy Number Variations (CNVs) are extremely abundant in the human genome. An enormous effort is currently on ...
5'–3'-UTR interactions regulate ...
Optimal induction of p53 protein after DNA damage requires RPL26-mediated increases in p53 mRNA translation. We report here the existence of a dsRNA ...
An Outbreak of Shigellosis due ...
Background: On June 16 and 17, 2007, the medical clinic of a prison in Isfahan, Iran received multiple reports of gastrointestinal illness among pris ...
One-Carbon Metabolism and Alzhe ...
Alzheimer’s disease (AD) represents the most common form of dementia in the elderly, characterized by progressive loss of memory and cognitive capaci ...
Causality, Randomness, Intellig ...
Because the basic unit of biology is the cell, biological knowledge is rooted in the epistemology of the cell, and because life is the salient charac ...
Small RNA Diversity in Plants a ...
MicroRNAs are a class of non-coding RNAs involved in post-transcriptional control of gene expression, either via degradation or translational inhibit ...
Plant Protein-Protein Interacti ...
Protein-protein interaction network represents an important aspect of systems biology. The understanding of the plant proteinprotein interaction netw ...
Revolver and Superior: Novel Tr ...
High-throughput sequencing of eukaryotic genomes has revived interest in the structure and function of repetitive genomic sequences, previously refer ...
Breast Cancer in the Personal G ...
Breast cancer is a heterogeneous disease with a complex etiology that develops from different cellular lineages, progresses along multiple molecular ...
Functional Annotation of Genes ...
We have used Gene Ontology (GO) and pathway analyses to uncover the common functions associated to the genes overlapping Copy Number Variants (CNVs) ...
Cytosine Methyltransferases as ...
Changes in DNA methylation patterns is a prominent characteristic of human tumors. Tumor cells display reduced levels of genomic DNA methylation and ...
Designing the Optimal Vaccine: ...
Many vaccines existing today provide strong protection against a wide variety of infectious organisms, and these consist of either live attenuated or ...
The Human Glioma-Associated Onc ...
Sonic hedgehog (Shh) signaling is critically important for embryogenesis and other cellular processes in which GLI transcription factors mediate the ...
Expressional Analysis and Role ...
Perception of stimuli and activation of a signaling cascade is an intrinsic characteristic feature of all living organisms. Till date, several signal ...