A single dose of DNA vaccine based on conserved H5N1 s ...
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A single dose of DNA vaccine ba ...
Background: Highly pathogenic avian influenza virus subtype H5N1 infects humans with a high fatality rate and has pandemic potential. Vaccination is ...
421.14 KB
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Optimised electroporation media ...
Background: Immunological therapies enhance the ability of the immune system to recognise and destroy cancer cells via selective killing mechanisms. ...
752.71 KB
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Recent Methods in Antimalarial ...
As malaria continues to be a worldwide problem due to increasing drug resistance, several drug susceptibility techniques have been reported in the li ...
249.24 KB
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Strategies for Overcoming Inher ...
Mutations in K-Ras are observed in approximately 40% of colon tumours. This has significant implications for predicting likelihood of response to the ...
249.45 KB
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Treatment with Imiquimod enhanc ...
Background: There is an urgent need to develop new innovative therapies for the control of advanced cancer. The combination of antigen-specific immun ...
874.24 KB
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The Macrophage Stimulating Prot ...
Macrophage Stimulating Protein (MSP) is the only known ligand for the receptor tyrosine kinase Ron. The MSP/Ron pathway is involved in several import ...
377.59 KB
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MicroRNA-21: From Cancer to Car ...
MicroRNA-21 (miR-21) expression is activated in multiple types of cancers, such as breast, liver, brain, prostate, myometrial cancers but also in car ...
414.50 KB
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High PIB Retention in Alzheimer ...
Background: New in vivo amyloid PET imaging tracers, such as 11C-PIB, provide possibilities to deeper understand the underlying pathological processe ...
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Pharmacogenomics of Human ABC T ...
Some genetic polymorphisms of human ABC transporter genes are reportedly related to the risk of certain diseases and patients’ responses to medicatio ...
466.79 KB
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Targeting Karyotypic Complexity ...
Multiple karyotypic abnormalities and chromosomal instability are characteristic features of many cancers that are relatively resistant to chemothera ...
591.82 KB
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Serum Serotonin Levels are Asso ...
The role of serotonin in contributing to viral clearance has not been investigated in patients with chronic hepatitis C (HCV). In this prospective st ...
1.05 MB
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Involvement of the Toxic AGEs ( ...
Diabetic vascular complications are leading causes of acquired blindness, end-stage renal failure, a variety of neuropathies, and accelerated atheros ...
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CpG ODN 1826 Enhances the Effic ...
Effectiveness of intrasplenic administration of plasmid vaccines has been of interest in vaccine research, because the spleen is strategically locate ...
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Evaluation of a Recombinant Rif ...
The possible role of the most abundant structural protein of Rift Valley fever virus (RVFV), the nucleocapsid protein (NP), in inducing protective im ...
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Safety of a Virosomal Adjuvante ...
Children suffering from chronic disease are at increased risk for complications and mortality caused by influenza. Influenza can be most effectively ...
116.55 KB
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Assessing the Environment for I ...
This paper presents findings from a study conducted in 2007 and 2008 in two states in India: Andhra Pradesh and Gujarat. The objectives of the study ...
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Rotavirus Hospital Surveillance ...
Background: In 2006 a rotavirus (RV) vaccine (Rota Teq®) was licensed for routine childhood immunization in the US. The aim of the present study was ...
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Heme Oxygenase-1 in Tumor Biolo ...
Heme oxygenase-1 (HO-1) degrades heme to carbon monoxide (CO), biliverdin, and ferrous iron. As HO-1 expression is highly increased by stressful cond ...
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Innate Immunity and Vaccine Adj ...
New vaccine technology has led to vaccines containing highly purified antigens with improved safety profiles, but increased antigen purity often resu ...
1.15 MB
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The Origin of Amerindians and t ...
The classical three-waves theory of American peopling through Beringia was based on a mixed anthropological and linguistic methodology. The use of mt ...
638.95 KB
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TWIST1 Gene: First Insights in ...
TWIST1 is thought to be a novel oncogene. Understanding the molecular mechanisms regulating the TWIST1 gene expression profiles in tumor cells may gi ...
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Regulation of the DNA Damage Re ...
Damage to the genetic material can affect cellular function in many ways. Therefore, maintenance of the genetic integrity is of primary importance fo ...
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Myotonic Dystrophies 1 and 2: C ...
Two multi-system disorders, Myotonic Dystrophies type 1 and type 2 (DM1 and DM2), are complex neuromuscular diseases caused by an accumulation of exp ...
532.68 KB
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Transcription Factor CHF1/Hey2 ...
We have previously found that overexpression of CHF1/Hey2 in the myocardium prevents the development of phenylephrine-induced hypertrophy. To identif ...
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Comparative Approach of the de ...
Over the second half of 20th century much research on lipogenesis has been conducted, especially focused on increasing the production efficiency and ...
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