High-resolution genomic profili ...
Male breast cancer (MBC) is extremely rare and poorly characterized on the molecular level. Using high-resolution genomic data, we aimed to characte ...
Role of CD200 expression in reg ...
Previous studies have confirmed that levels of CD200 expression on the cells of the transplantable EMT6 mouse breast cancer line are increased marke ...
Prognostic significance of meth ...
Free circulating DNA is increased in the serum/ plasma of cancer patients, and methylation of certain genes has been found to be characteristic for ...
Soy intake in association with ...
It has been suggested that soy food and its components may relieve menopausal symptoms (MPS) including hot flashes, night sweats, and vaginal drynes ...
SOSTDC1 differentially modulate ...
Sclerostin domain containing 1 (SOSTDC1) protein regulates processes from development to cancer by modulating activity of bone morphogenetic protein ...
Role of PTEN promoter methylati ...
Tamoxifen (TAM) resistance is a serious clinical problem in the treatment of breast cancer. Here, we found that S-adenosylmethionine (SAM) and DNA m ...
Prediction of lymph node involv ...
The aim of this study was to investigate whether lymph node involvement in breast cancer is influenced by gene or miRNA expression of the primary tu ...
PH006, a novel and selective Sr ...
The central role of Src in tumor progression and metastasis has validated it as an attractive therapeutic target for the treatment of human breast c ...
The associations between two po ...
The association between single-nucleotide polymorphisms (SNPs) in the interleukin-10 (IL-10) gene promoter and breast cancer risk is still ambiguous ...
Acquisition of metastatic tissu ...
Biopsies of metastatic tissue are increasingly being performed. Bone is the most frequent site of metastasis in breast cancer patients, but bone rem ...
Oral administration of benzyl-i ...
Benzyl-isothiocyanate (BITC) is a hydrolysis product of glucotropaeolin, a compound found in cruciferous vegetables, and has also been shown to have ...
MicroRNA profiles of healthy ba ...
In order to determine the microRNA expression pattern in normal basal and luminal breast epithelium and to analyze the relationship of this expressi ...
Estrogen receptor b causes a G2 ...
The role of estrogen receptor beta (ERb) in breast cancer is unclear. ERb is considered to have a protective role in breast cancer development based ...
Post-lumpectomy intracavitary r ...
Liposomes are recognized drug delivery systems with tumor-targeting capability. In addition, therapeutic or diagnostic radionuclides can be efficien ...
Presence of MMTV-like env gene ...
Park et al. 2010 (No evidence of MMTV-like env sequences in specimens from the Australian Breast Cancer Family Study, Breast Cancer Research and Tre ...
No significant association resu ...
We have read with great interest the article ‘‘No significant association between the TP53 codon 72 polymorphism and breast cancer risk: a meta-anal ...
Comprehensive CYP2D6 genotype a ...
The association between CYP2D6 genotype and outcome in breast cancer patients treated with adjuvant tamoxifen remains controversial. We assessed the ...
A 10-year follow-up of treatmen ...
We compare long-term outcomes in patients with node negative early stage breast cancer treated with breast radiotherapy (RT) without the axillary RT ...
Two novel variants in the 30UTR ...
For the majority of breast and/or ovarian cancer patients tested for BRCA1/2 genes, mutation screening of the coding regions remains negative. Micro ...
Poly(ADP-ribose) polymerase-1 m ...
Although poly(ADP-ribose) polymerase-1 (PARP1) inhibition is a recent promising therapy in breast cancer, PARP1 expression in this disease is not kn ...
A recombination-based method to ...
Many missense variants in BRCA1 are of unclear clinical significance. Functional and genetic approaches have been proposed for elucidating the clini ...
Gene expression array testing o ...
Archived formalin-fixed, paraffin embedded (FFPE) tissues constitute a vast, well-annotated, but underexploited resource for the molecular study of ...
A high prevalence of BRCA1 muta ...
The Bahamas is a group of islands in the Caribbean with a high incidence of early onset breast cancer. In isolated populations, the identification o ...
LFA-1 gene polymorphisms are as ...
The infiltrative duct carcinoma (IDC) is the most common malignant breast cancer in females and genetic factors appear to play a significant role in ...
No evidence for an association ...
Breast cancer represents a serious public health problem worldwide, for its high incidence, morbidity, mortality, and its high cost treatment. It is ...