Presence of Foxp3 expression in tumor cells predicts be ...
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Presence of Foxp3 expression in ...
The Forkhead Box Protein 3 is highly expressed not only in regulatory T cells, but also in tumor cells, acting as a transcriptional repressor of bre ...
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Dead-box or black-box: is DDX1 ...
In this issue of Breast Cancer Research and Treatment, Germain et al. evaluate the potential role of DEAD-box 1 (DDX1) as an independent marker of p ...
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Inhibition of focal adhesion ki ...
Acquired resistance to endocrine therapy in breast cancer is a major clinical problem. Previous reports have demonstrated that cell models of acquir ...
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Overexpression of the urokinase ...
uPAR, the three-domain membrane receptor of the serine protease urokinase, plays a crucial role in tumor growth and metastasis. Several mRNA splice ...
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Clinical significance of high f ...
Increased expression and activation of focal adhesion kinase (FAK) was reported to be an unfavorable factor in various human cancers, including brea ...
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Role of ferritin alterations in ...
Breast cancer is the most common malignancy in women. Successful treatment of breast cancer relies on a better understanding of the molecular mechan ...
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Classical membrane progesterone ...
In this article, we demonstrate the expression of functional progesterone binding sites at the cell membrane in murine mammary carcinomas that are s ...
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Cacalol, a natural sesquiterpen ...
We previously isolated cacalol as a free radical- scavenging compound from Cacalia delphiniifolia which is a traditional Asian herbal plant and is b ...
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Decreased expression of EZH2 is ...
The purpose of this study is to investigate EZH2 in a large series of breast cancer patients for its prognostic and predictive value, and to evaluat ...
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Dual targeting of EphA2 and ER ...
Overexpression and altered function of EphA2 receptor tyrosine kinase are critical in the progression of breast cancer and provide a target for brea ...
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The management of ductal intrae ...
The management of ductal intraepithelial neoplasia (DIN) has substantially changed over the past 30 years, as its incidence has increased (from 2–3% ...
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Preclinical evaluation of nucle ...
Prevention and early detection of breast cancer are the major prophylactic measures taken to reduce the breast cancer related mortality and morbidit ...
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BRCA1 promoter methylation in p ...
BRCA1 promoter methylation reportedly plays an important part in the pathogenesis of human breast cancer. In the present study, we investigated whet ...
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Mutations and polymorphic BRCA ...
We previously showed that about 80% of breast cancer patients at high risk to carry mutation in BRCA genes presented at least one polymorphism in th ...
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Time to move forward from ‘‘fir ...
For clinicians, it has been clear for many years that breast cancer patients with the same clinical and pathological characteristics can have divers ...
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Microcephalin is a new novel pr ...
The authors have investigated the expression of the microcephalin (MCPH1) protein to evaluate its prognostic importance in breast cancer. Microcepha ...
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Pachymic acid impairs breast ca ...
Pachymic acid (PA), a lanostane-type triterpenoid derived from Poria cocos, possesses demonstrated anti-inflammatory and anti-cancer activities. Non ...
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Identification of genes associa ...
Here we evaluated the cytotoxic effects of a combination of the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) and taxanes in ...
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Uptake of 2-NBDG as a method to ...
This study quantifies uptake of a fluorescent glucose analog, (2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4- yl)amino)-2-deoxyglucose) (2-NBDG), in a large ...
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DEAD box 1: a novel and indepen ...
Breast cancer is a heterogeneous disease characterized by diverse molecular signatures and a variable response to therapy. Clinical management of br ...
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Cytokeratin 5 positive cells re ...
A majority of breast cancers are estrogen receptor (ER) positive and have a luminal epithelial phenotype. However, these ER? tumors often contain h ...
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Stimulation of retinoic acid-in ...
The sodium iodide symporter (NIS) mediates the active iodide uptake in the thyroid gland as well as lactating breast tissue. Recently, we reported s ...
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Gene expression profile predict ...
Prognosis of early beast cancer is heterogeneous. Today, no histoclinical or biological factor predictive for clinical outcome after adjuvant anthra ...
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Transient over-expression of es ...
Estrogen receptor-a (ERa) positive breast cancer frequently responds to inhibitors of ERa activity, such as tamoxifen, and/or to aromatase inhibitor ...
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Functional implication of TRAIL ...
Recently, TRAIL function has been elucidated beyond its known classical role of mediating cellular homeostasis and immune surveillance against trans ...
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