The Pharmacokinetics and Pharmacodynamics of Levodopa i ...
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The Pharmacokinetics and Pharma ...
Levodopa , a prodrug of dopamine, remains to be one of the main drugs in the treatment of Parkinson’s disease. All current levodopa products are form ...
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A New Glucocorticoid Hypothesis ...
The original glucocorticoid (GC) hypothesis of brain aging and Alzheimer’s disease proposed that chronic exposure to GCs promotes hippocampal aging a ...
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Nutritional Modulation of Termi ...
Findings with experimental rodent models reveal that exposures to dietary factors during the in utero and pubertal periods when the mammary gland is ...
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Mechanism of Action and Potenti ...
“Drinking several cups of green tea a day keeps the doctor away” is clearly an overstatement. However, extensive research has revealed that the predo ...
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ECRG1, a novel esophageal gene, ...
ECRG-1 (esophageal cancer-related gene 1) has been previously found to be down-regulated in human esophagus cancer. Transient expression of green fl ...
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Dendrimers and Dendritic Polyme ...
Nearly 3 decades ago, a dendritic structure was stepwise synthesized for the first time as a new type of molecules with promising applications. Durin ...
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Unique Applications of Novel An ...
Candida albicans is a commensal fungal organism that can over-proliferate and cause disease in the appropriate host setting. C. albicans can cause ir ...
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IMGT Colliers de Perles: Standa ...
IMGT®, the international ImMunoGeneTics information system® (http://imgt.cines.fr) provides a common access to expertly annotated data on the genome, ...
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Quantum Dot Nanocrystals and Su ...
Resonance Energy Transfer (RET) plays an important role, both scientifically and commercially, in diagnostics and high throughput screening. For qual ...
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IMGT Colliers de Perles: Standa ...
IMGT®, the international ImMunoGeneTics information system® (http://imgt.cines.fr) provides a common access to expertly annotated data on the genome, ...
898.46 KB
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The Phosphoinositide 3-Kinase P ...
The phosphoinositide 3-kinase (PI3K) pathway is frequently activated in human cancer and represents an attractive target for therapies based on small ...
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Cutaneous leishmaniasis before ...
Background: Cutaneous leishmaniasis is an endemic infectious disease in Iran caused by flagellated protozoa. The most common cause of cutaneous leish ...
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Structural and Functional Deter ...
Alzheimer’s disease is the most common form of neurodegenerative diseases in humans, characterized by the progressive accumulation and aggregation of ...
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Advances on the Understanding o ...
Although Alzheimer’s disease (AD) was first discovered a century ago, we are still facing a lack of definitive diagnosis during the patient’s lifetim ...
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Genetic Mechanisms and Aberrant ...
Gastric adenocarcinoma occurs via a sequence of molecular events known as the Correa’s Cascade which often progresses over many years. Gastritis, typ ...
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The GNAS Locus: Quintessential ...
The currently estimated number of genes in the human genome is much smaller than previously predicted. As an explanation for this disparity, most ind ...
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The Basic Biology of BACE1: A K ...
Alzheimer’s disease (AD) is an intractable, neurodegenerative disease that appears to be brought about by both genetic and non-genetic factors. The n ...
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HLA Genes in Mayos Population f ...
HLA class I and class II alleles have been studied in 60 unrelated people belonging to Mayos ethnic group, which lives in the Mexican Pacific Sinaloa ...
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Validation of Inference Procedu ...
The availability of high-throughput genomic data has motivated the development of numerous algorithms to infer gene regulatory networks. The validity ...
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Maps of cis-Regulatory Nodes in ...
The availability of complete human and other metazoan genome sequences has greatly facilitated positioning and analysis of various genomic functional ...
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Genetics of Bacterial Alginate: ...
Bacterial alginate genes are chromosomal and fairly widespread among rRNA homology group I Pseudomonads and Azotobacter. In both genera, the genetic ...
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The Application of Single Nucle ...
The development of microarray technology has had a significant impact on the genetic analysis of human disease. The recently developed single nucleot ...
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EGFR Intron Recombination in Hu ...
The epidermal growth factor receptor (EGFR) is a membrane-bound, 170 kDa, protein tyrosine kinase that plays an important role in tumorigenesis. The ...
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EGFR Intron Recombination in Hu ...
The epidermal growth factor receptor (EGFR) is a membrane-bound, 170 kDa, protein tyrosine kinase that plays an important role in tumorigenesis. The ...
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The HLA Region and Autoimmune D ...
The HLA region encodes several molecules that play key roles in the immune system. Strong association between the HLA region and autoimmune disease ( ...
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