Nephronophthisis
Intradialytic hypotension
Intradialytic hypotension (IDH) is common in children during conventional, 4 hour haemodialysis (HD) sessions. The declining blood pressure (BP) was ...
Diagnosis and management of chi ...
A number of syndromic disorders have renal cysts as a component of their phenotypes. These disorders can generally be distinguished from autosomal d ...
Management of toxic ingestions ...
Although rare, renal replacement therapy (RRT) for the treatment of the metabolic, respiratory and hemodynamic complications of intoxications may be ...
PPARم and chronic kidney diseas ...
Peroxisome proliferator-activated receptor-م (PPARم) agonists, exemplified by the thiazolidinediones (TZDs), have been used extensively for their be ...
Parathyroid hormone and growth ...
Growth failure is common in children with chronic kidney disease, and successful treatment is a major challenge in the management of these children. ...
Consequences and therapy of the ...
Metabolic acidosis is common in patients with chronic kidney disease (CKD), particularly once the glomerular filtration rate (GFR) falls below 25 ml ...
Role of fibroblast growth facto ...
Fibroblast growth factor receptors (Fgfrs) are expressed throughout the developing kidney. Several early studies have shown that exogenous fibroblas ...
Nocturnal enuresis—theoretic ba ...
Nocturnal polyuria, nocturnal detrusor overactivity and high arousal thresholds are central in the pathogenesis of enuresis. An underlying mechanism ...
Heat shock proteins in chronic ...
Heat shock proteins (HSP) form a heterogenous, evolutionarily conserved group of molecules with high sequence homology. They mainly act as intracell ...
Uraemic vasculopathy in childre ...
Since the inception of pediatric dialysis programmes nearly 50 years ago, there have been vast improvements in both the technology and expertise in ...
Aciclovir and Varicella-zoster- ...
Clear recommendations for the management of acute varicella-zoster virus (VZV) infections for cases of significant exposure and the use of prophylac ...
Advances in our understanding o ...
Glomerular thrombotic microangiopathy is a hallmark feature of haemolytic uraemic syndrome, the leading cause of acute renal failure in childhood. T ...
The genetic components of idiop ...
Nephrolithiasis is a cause of significant morbidity and medical care expenses worldwide. Its prevalence has increased steadily during the last three ...
Nephronophthisis
Nephronophthisis (NPHP) is an autosomal recessive cystic kidney disease and the most frequent genetic cause of end-stage renal disease up to the thi ...
Vitamin D, chronic kidney disea ...
It is now about 40 years ago that the mechanism of renal 1-ل-hydroxylation of vitamin D was discovered and characterized. After this seminal observa ...
Control of mammalian kidney dev ...
The kidney is the most common site of congenital malformations that result in impaired renal function. Yet, the molecular mechanisms that control re ...
Problems with 'focal segme ...
The term 'focal segmental glomerulosclerosis (FSGS)' has been applied to many different conditions. All classifications of 'FSGS', including those d ...
Genetic susceptibility to renal ...
Identifying patients who may develop renal scarring after urinary tract infections (UTI) remains challenging, as clinical determinants explain only ...
Clinical and Molecular Insights ...
Patients with tuberous sclerosis complex are at great risk of developing renal lesions as part of their disease. These lesions include renal cysts a ...
The primary cilium in different ...
Primary cilia are specialized organelles consisting of an axoneme anchored to the plasma membrane through the basal body consisting of two centriole ...
Acute kidney injury in childhoo ...
While emerging evidence indicates that the incidence of both acute kidney injury (AKI) and chronic kidney disease (CKD) in children is rising and th ...
“Virtual Pediatric Renal Grand ...
Sirs, With the availability of the newer web tools in Web 3.0, such as Blogs, Wikis, Twitter and Podcasts, physicians are able to interact and diss ...
Residual renal function assessm ...
Su Jin Kim and coworkers from Korea published an important study on the relationship of residual renal function (RRF) and cystatin in pediatric peri ...
Post-streptococcal acute glomer ...
Post-streptococcal acute glomerulonephritis (PSAGN) is one of the most important and intriguing conditions in the discipline of pediatric nephrology ...
Pandemic H1N1 influenza A infec ...
Atypical hemolytic uremic syndrome (aHUS) is caused by mutations resulting in an exceedingly active alternative complement pathway. While today more ...