The spinal muscular atrophy mouse model, SMAD7, display ...
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The spinal muscular atrophy mou ...
Spinal muscular atrophy (SMA) is a neurodegenerative disease resulting from decreased levels of survival motor neuron 1 (SMN1) protein. Reduced SMN1 ...
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Factors affecting Ab plasma lev ...
Previous studies of Ab plasma as a biomarker for Alzheimer’s disease (AD) obtained conflicting results. We here included 715 subjects with baseline ...
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The cerebellar component of Fri ...
Lack of frataxin in Friedreich’s ataxia (FRDA) causes a complex neurological and pathological phenotype. Progressive atrophy of the dentate nucleus ...
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Widespread non-central nervous ...
Fragile X-associated tremor/ataxia syndrome (FXTAS) is an adult-onset neurodegenerative disorder generally presenting with intention tremor and gait ...
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Postsynaptic degeneration as re ...
Impairment of synaptic plasticity underlies memory dysfunction inAlzheimer’s disease (AD). Molecules involved in this plasticity such as PSD-95, a m ...
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Enhancement of endogenous neuro ...
Cerebral ischemia stimulates endogenous neurogenesis. However, the functional relevance of this phenomenon remains unclear because of poor survival ...
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Vasculitis-like neuropathy in a ...
Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease with variable involvement of other systems. A pathogenetic role of immune-mediat ...
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Macrophage migration inhibitory ...
Macrophage migration inhibitory factor (MIF), which inhibits apoptosis and promotes angiogenesis, is expressed in cancers suppressing immune surveil ...
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Peroxisomal alterations in Alzh ...
In Alzheimer’s disease (AD), lipid alterations are present early during disease progression. As some of these alterations point towards a peroxisoma ...
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Globular glial tauopathies (GGT ...
A number of recent studies have described cases with tau-positive globular oligodendroglial inclusions (GOIs) and such cases have overlapping pathol ...
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Comparison of SHR, WKY and Wist ...
Spontaneously hypertensive rats (SHR) and its counterpart, the Wistar-Kyoto rats (WKY), are probably the most often used animal model of ADHD. Howev ...
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Antecedents of ADHD: a historic ...
The concept of ADHD has evolved gradually and still carries some traces of its origins. The idea of uncontrolled behaviour as a medical problem aros ...
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A pilot study: differential eff ...
To examine the effects of methylphenidate- OROS (MPH-OROS) on working memory (WM) and attention functions in children with attention-deficit hypera ...
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Childhood obesity and parental ...
ADHD prevalence has risen in parallel with rising prevalence of pregnancy smoking and childhood obesity. The objective was to determine the epidemio ...
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ADHD and comorbid conduct probl ...
Attention-deficit/hyperactivity disorder (ADHD) is a common child and adolescent disorder that is associated with negative outcomes (e.g., emotional ...
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Neurocognitive correlates of ad ...
We established a neuropsychological testing profile among Turkish adults presenting with ADHD controlling for general intelligence and comorbid psyc ...
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Olfactory and gustatory sensiti ...
Recently, research on olfactory functions in attention-deficit/hyperactivity disorder (ADHD) has become prominent, whereas gustation has never been ...
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Mothers of children with attent ...
This study focuses on mothers of children diagnosed with attention deficit/hyperactivity disorder (ADHD) and sets out (1) to characterize dimensions ...
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Long-term open-label response t ...
A three-year open-label study of atomoxetine in adults with ADHD followed two multicenter, double-blind trials. In the double-blind trials, female g ...
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An exploration of the associati ...
Intra-individual variability of the characteristics of children with attention-deficit hyperactivity (ADHD) may reflect compromised glial energy sup ...
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Potential cognitive endophenoty ...
Endophenotypes are neurobiological markers cosegregating and associated with illness. These biomarkers represent a promising strategy to dissect ADH ...
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No evidence for association bet ...
Noradrenergic neurotransmission influences executive functions, attentional performance, and general alertness, involving neuronal networks affected ...
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Training of attention functions ...
Pharmacological treatment of children with ADHD has been shown to be successful; however, medication may not normalize attention functions. The pres ...
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A potential diagnostic blood te ...
Diagnosis of attention deficit hyperactivity disorder (ADHD) in children, adolescents, and adults remains controversial. Dramatic growth in the diag ...
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Multitasking in adults with ADH ...
Adults with ADHD have problems in everyday multitasking situations presumably because of deficits in executive functions. The present study aims to ...
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