A gene expression signature identifies two prognostic s ...
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A gene expression signature ide ...
Prognosis of basal breast cancers is poor but heterogeneous. Medullary breast cancers (MBC) display a basal profile, but a favorable prognosis. We h ...
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Prospective randomized trial of ...
A previous randomized trial (CALGB 9344/ Intergroup 0148) compared four cycles of adjuvant doxorubicin/ cyclophosphamide (AC) to four cycles of AC p ...
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Immediate reconstruction with i ...
Physicians are still concerned about the oncological safety regarding immediate breast reconstruction (IBR) in breast cancer patients. This study ai ...
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Phase I trial of oral mTOR inhi ...
To determine the feasible dose and schedule for everolimus, an oral mTOR inhibitor, combined with vinorelbine and trastuzumab for patients with HER2 ...
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Bone mineral density and risk o ...
To determine if higher bone mineral density (BMD) is a risk factor for breast cancer in women age 50 years and older. 37,860 women C50-year old with ...
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A single-center, prospective an ...
Over the past four decades, chemotherapy has played an important role in prolonging survival in breast cancer patients. However, it may also result ...
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Clinical potential of the mTOR ...
The mammalian target of rapamycin (mTOR) and its substrates S6K1 and S6K2 regulate cell growth, proliferation, and metabolism through translational ...
دانلود 4
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Detection and clinical relevanc ...
The factors determining the clinical relevance of disseminated tumor cells (DTC) in breast cancer patients are largely unknown. Here we compared the ...
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Benefits of early and prolonged ...
Response to fulvestrant and survival in postmenopausal hormone-sensitive advanced breast cancer was investigated within a non-randomized, In-Practic ...
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Neoadjuvant chemotherapy for br ...
Understanding and translating results from the highly regulated and uniform environment of therapeutic trials to everyday patient care are one of th ...
دانلود 1
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Bilateral breast cancer: analys ...
There has been conflicting evidence on the impact of bilateral breast cancer (BBC) on the survival and management of patients. The objectives of thi ...
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Mouse mammary tumor like virus ...
Mouse mammary tumor virus (MMTV) has been a long standing candidate as a potential cause of some human breast cancers. Forty years ago, electron mic ...
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Immunohistochemistry compared t ...
The purpose of this study is to compare immunohistochemistry (IHC) and cytosol-based assays for determination of estrogen receptor (ER) and predicti ...
دانلود 1
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Lobular and non-lobular breast ...
Invasive lobular carcinoma (ILC) accounts for 8–14% of all breast cancers and carries distinct prognostic and biologic implications. The goal of our ...
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Strength training stops bone lo ...
Targeted exercise training could reduce risk factors for fracture and obesity-related diseases that increase from breast cancer treatment, but has n ...
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Vascular endothelial growth fac ...
A cross talk between tyrosine kinase receptors and mitogen-activated protein kinases (MAPKs) is proposed as involved in endocrine resistance. We wan ...
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Let-7a regulation of insulin-li ...
Expression of certain microRNA genes is regulated by DNA methylation, which in turn affects the activities of their downstream molecules. Our previo ...
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Prognosis in women with small ( ...
Knowledge is limited about prognostic significance of breast cancer subtypes among women with small invasive node-negative breast tumours. We explor ...
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The mammalian target of rapamyc ...
mTOR plays a key role in tumor cell cycle control, proliferation, and survival. RAD001 (everolimus) is a novel macrolide that inhibits mTOR and thus ...
دانلود 1
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Disseminated tumor cells: the m ...
Bone marrow DTC in breast cancer It is a tenet of breast cancer biology that patients with primary (Stages I–III) breast cancer can harbor residual ...
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Comparison of the prognostic an ...
The Oncotype DX Recurrence Score (RS) is a validated genomic predictor of outcome and response to adjuvant chemotherapy in ER-positive breast canc ...
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Phase I/II study of sorafenib w ...
We evaluated the use of sorafenib to overcome resistance to aromatase inhibitors (AIs) in patients with metastatic breast cancer who had disease rec ...
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Mitotic activity and bone marro ...
The purpose of this article is to investigate the prognostic value of the mitotic activity index (MAI) and the presence of disseminated tumor cells ...
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Association between polymorphis ...
Epidemiological studies have evaluated the association between ataxia telangiectasia mutated (ATM) gene polymorphisms and breast cancer risk. Howeve ...
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Breast cancer screening in BRCA ...
Breast cancer screening is offered to BRCA1 and BRCA2 mutation carriers from the age of 25 years because of their increased risk of breast cancer. A ...
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