Genetics and Immunopathogenesis of IgA Nephropathy
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Genetics and Immunopathogenesis ...
IgA nephropathy (IgAN) is the most common glomerulonephritis in the world. The hallmark of IgAN is underglycosylation in the hinge region of IgA1. I ...
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Cutting Edge Issues in Autoimmu ...
Autoimmune gastritis is the outcome of a pathological CD4 T cell-mediated autoimmune response directed against the gastric H/K-ATPase. Silent initia ...
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Pregnancy Outcomes in Japanese ...
Systemic lupus erythematosus (SLE) is mainly a disease of fertile women and the coexistence of pregnancy is by no means a rare event. How SLE and it ...
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The Etiology of Paraneoplastic ...
Although they may sometimes appear similar, paraneoplastic autoimmunity has a unique pathogenesis, different from the classical autoimmune diseases ...
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Hydroxychloroquine: From Malari ...
Quinine was first recognized as a potent antimalarial agent hundreds of years ago. Since then, the beneficial effects of quinine and its more advanc ...
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Cutting Edge Issues in Rheumati ...
Although the incidence of acute rheumatic fever and rheumatic heart disease has decreased significantly in regions of the world where antibiotics ar ...
560.67 KB
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Auto-antibodies as Emergent Pro ...
During the last 15 years, a growing body of evidence supported the fact that auto-antibodies represent not only emergent markers but also active med ...
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Therapeutic Implications of a B ...
Excessive Th2 cell signaling and IgE production play key roles in the pathogenesis of atopic dermatitis (AD). Yet, recent information suggests that ...
615.87 KB
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Childhood Femoral Head Osteonec ...
Femoral head osteonecrosis (FHO) is potentially a devastating condition of the hip joint that can affect children and adults. The most serious outco ...
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Cysteine Cathepsins and the Ske ...
Cysteine cathepsins are lysosomal proteases with housekeeping as well as tissue-specific functions. One of their specialized functions includes the ...
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Osteonecrosis of the Hip in Adu ...
Atraumatic osteonecrosis in adults most commonly presents in the hip. The specific etiology and pathogenesis is often uncertain, and we will review ...
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Thyroid Cathepsin K: Roles in P ...
The human genome encodes 11 cysteine cathepsins belonging to the papain-like family of cysteine peptidases that are known predominantly as endo-lyso ...
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Cathepsin L in Normal and Patho ...
Cathepsin L is a ubiquitous lysosomal cysteine endopeptidase that is mainly involved in the metabolic turnover of intracellular proteins. However, i ...
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Pitfalls to Avoid and Advanceme ...
The optimal treatment for osteonecrosis of the hip is contingent on early and accurate diagnosis. Magnetic resonance imaging (MRI) has become the re ...
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The Emerging Relevance of the C ...
Cathepsin S is a lysosomal cysteine protease that has been shown to play a key role in MHC class II antigen presentation. Consequently, it has been ...
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Bisphosphonates and Osteonecros ...
The beneficial effects of the nitrogen-containing bisphosphonate drugs have been clearly defined, especially for the treatment for osteoporosis, met ...
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Cathepsins S, L, and K and Thei ...
Members of the cysteine protease cathepsin family play an important part in human pathophysiology. Among those, Cathepsin K has a major role in enzy ...
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Osteoradionecrosis of the Jaws
Osteoradionecrosis (ORN) is one of the most serious oral complications of head and neck cancer treatment with radiotherapy. There is bone tissue nec ...
دانلود 1
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Cysteine Protease Cathepsins in ...
Extracellular matrix remodeling is an important mechanism in the initiation and progression of cardiovascular diseases. Cysteine protease cathepsins ...
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Ionizing Radiation and Bone Los ...
Damage to normal, nontumor bone tissue following therapeutic irradiation increases the risk of fracture among cancer patients. For example, women tr ...
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Cysteine Cathepsins: Markers an ...
There is now growing evidence that lung cysteine cathepsins take part in several biological processes and pulmonary homeostasis, although their exac ...
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Animal Models of Osteonecrosis
Osteonecrosis is an uncommon but significant musculoskeletal disease characterized by focal areas of dead bone that often fail to heal even with int ...
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The association of Raynaud’s sy ...
Rheumatoid arthritis (RA) has traditionally been included among the diseases associated with Raynaud’s syndrome (RS). The prevalence of RS in patien ...
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Evaluation of current therapeut ...
Behçet’s disease (BD) is a chronic relapsing vasculitis with multifunctional pathogenesis. The mucocutaneous and ocular lesions are the commonest ma ...
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An overview of commonly used ra ...
Despite the advent of magnetic resonance imaging and musculoskeletal ultrasound, the plain radiographs of the hands and feet remain an important too ...
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