The Role of Bone Marrow and Vis ...
The protective effect of total fat mass on bone mineral density (BMD) has been challenged with studies showing no or negative association after adju ...
The Role of Risk Communication ...
Risk assessment and communication of risk are essential components in the care of patients with osteoporosis. The risk of fracture in an untreated p ...
Use of Strontium as a Treatment ...
Given its increasing incidence and serious complications, osteoporosis requires safe and effective long-term treatment. Strontium ranelate (SR), a n ...
Role of Endocrine and Paracrine ...
There appears to be no unique mechanically sensitive pathway by which changes in bone loading regulate bone mass and architecture to ensure adequate ...
Effects of Anti-osteoporosis Me ...
A number of fractures are complicated by impaired healing. This is prevalent in certain risk groups such as elderly, osteoporotics, postmenopausal w ...
Osteoporosis in Men: What has C ...
Osteoporosis in men is finally receiving some attention; it has been realized that men are more likely to die after hip fracture. Methods for screen ...
Role of Altered Signal Transduc ...
Heterotopic ossification is a pathologic condition in which bone tissue is formed outside of the skeleton, within soft tissues of the body. The extr ...
Choosing a Treatment for Patien ...
The occurrence of a fragility fracture is an opportunity to recognize osteoporosis and begin treatment to reduce the risk of another fracture. Howev ...
Optimal Use of Vitamin D When T ...
Inadequate serum 25-hydroxyvitamin D (25[OH] D) concentrations are associated with muscle weakness, decreased physical performance, and increased pr ...
Bone Structural Components Regu ...
Tumors such as breast, lung, and prostate frequently metastasize to bone, where they can cause intractable pain and increase the risk of fracture in ...
Diagnostic Thresholds in Osteop ...
Clinical trials are used to determine the efficacy and safety of a medication prior to approval for commercial use and to influence the prescribing ...
Hematopoietic Cell Regulation o ...
The last several decades have revealed numerous interactions between cells of the hematopoietic lineage and osteoblasts (OBs) of the mesenchymal lin ...
FGF23 in Skeletal Modeling and ...
Fibroblast growth factor 23 (FGF23), a hormone primarily produced in bone cells, targets the kidney to accelerate phosphate excretion into the urine ...
Osteopenia: A Diagnostic and Th ...
We discussed whether we are able to select a subgroup of patients with osteopenia having a high fracture risk, in which anti-osteoporotic drug treat ...
Epidemiology of Cancer Pain
About half of cancer patients experience pain, most commonly due to their primary cancer. Pain severity is at least moderate for most patients exper ...
What Differences Exist in the A ...
Chiari type I malformation is found in 1 out of 20 magnetic resonance imaging (MRI) studies. Isolated tonsillar herniation is of limited utility and ...
Are Antiepileptic Drugs Used in ...
Three antiepileptic drugs (AEDs), valproic acid, gabapentin, and topiramate (TPM), are used frequently in the prophylactic treatment of migraines. I ...
Interventional Management for C ...
Cancer pain is a distressing result of disease, both primary and metastatic, as well as complications caused by cancer treatment. Medication managem ...
Deep Brain Stimulation and Moto ...
Deep brain stimulation (DBS) is an important treatment option for neuropathic pain. DBS has a considerable history, and it can be used successfully ...
Maladaptive Opioid Use Behavior ...
is well established that opioids are broadly effective for chronic pain. Although there is some agreement that stable, moderate dosing is desirable; ...
Updated Perspectives on Neuroge ...
Pain represents a foremost feature of neurogenic thoracic outlet syndrome (NTOS). Similar to other persistent pain conditions, the physical discomfo ...
ICHD-3: What Changes Do We Need ...
Based on publications on migraine in the medical literature after 2004, the third edition of the International Classification of Headache Disorders ...
Managing Breakthrough Pain
Breakthrough cancer pain (BTcP) has been defined as a transitory increase in pain intensity on a baseline pain of moderate intensity in patients on ...
Alcohol and Migraine: What Shou ...
Alcoholic drinks are a migraine trigger in about one third of patients with migraine in retrospective studies on trigger factors. Many population st ...
Effective Treatments for Pain i ...
By 2050, the number of older persons across the globe will exceed the number of younger people for the first time in history. Chronic conditions, es ...