Recently abused b-keto derivati ...
b-Keto derivatives of 3,4-methylenedioxyphenylalkylamines (bk-MDPAs), especially 2-methylamino- 1-(3,4-methylenedioxyphenyl)propan-1-one (methylone) ...
Identification and quantitation ...
Six cannabimimetic indoles have been identified as adulterants in herbal or chemical products being sold illegally in Japan, with four of the compou ...
Mushroom toxins: a forensic tox ...
Mushrooms are ubiquitous in the world. Amateur hunters harvest mushrooms growing in forests to enjoy eating them as seasonal delicacies, and occasio ...
Detection of saxitoxin in count ...
The neurotoxin saxitoxin (STX) is registered in the list of the Chemical Weapons Convention. In preparation against potential terrorism by STX use, ...
Identification and quantitation ...
During our careful surveillance of unregulated drugs, we found five new compounds used as adulterants in herbal and drug-like products obtained via ...
Imaging of methamphetamine inco ...
Matrix-assisted laser desorption ionization (MALDI)–time-of-flight (TOF) mass spectrometry (MS) was used for visual demonstration of methamphetamine ...
In vivo incorporation of fenflu ...
The incorporation profiles for fenfluramine (Fen) and its metabolite norfenfluramine (Norf) into black hair and white hair of Zucker rats and into w ...
Differential inhibition of huma ...
Inhibitory effects of D9-tetrahydrocannabinol (D9-THC), cannabidiol (CBD), and cannabinol (CBN) on the catalytic activities of human recombinant cyt ...
Identification and quantitation ...
During our careful survey of unregulated drugs in Tokyo, a new compound was disclosed as an adulterant in herbal and powder products. This compound ...
A study on mechanisms of toxic ...
Ciguatoxins, a group of virulent marine toxins, are bound to ‘‘site 5’’ inside voltage-dependent sodium channels and alter their kinetics dramatical ...
Possible involvement of Cyp3a e ...
D8-Tetrahydrocannabinol (THC) and D9-THC were mainly oxidized on the pentyl side chain at the 40-position by mouse brain microsomes. 50-Hydroxy-THCs ...
Identification and quantitation ...
During our careful surveillance of unregulated drugs in January to February 2011, we found two new compounds used as adulterants in herbal products ...
Optimization of simultaneous an ...
Recently, liquid chromatography–mass spectrometry (LC–MS) has been recognized as a useful method to analyze tetrodotoxin (TTX), the primary toxin fo ...
A model system for prediction o ...
The in vitro metabolisms of 4-bromo-2,5- dimethoxyphenethylamine (2C-B), 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT), and 2,5-dimethoxy-4- pro ...
8-Hydroxy-20-deoxyguanosine and ...
Arsenic trioxide (ATO) is an effective agent for acute promyelocytic leukemia (APL). In this study, the concentrations of dimethylarsinic acid (DMA) ...
Oripavine as a new marker of op ...
During our extensive surveillance of opiates in urine specimens of opium users, we noticed the appearance of an unknown peak (compound X) in total i ...
Determination of acephate and m ...
A simple and reliable method to determine acephate and methamidophos in mammalian tissues is presented. The method includes solid-phase extraction o ...
Construction of the vessel-coll ...
According to the self-discipline of traditional Chinese medicine, vessel-collateral theory was constructed systematically, which was important to imp ...
Bioartificial liver devices: Pe ...
Acute liver failure remains a significant cause of morbidity and mortality. Bioartificial liver (BAL) devices have been in development for more than ...
Practices, challenges, and oppo ...
Traditional Chinese medicine (TCM) has become widely used in the treatment of acquired immune deficiency syndrome (AIDS) in China in recent years. In ...
Integrated management of cardia ...
The prevalence of the risk factors and the risk of cardiac failure are both increasing in China. This might be the consequence of the changes of the ...
Developments in cancer preventi ...
Through the joint efforts of several generations of practitioners in traditional Chinese medicine (TCM) and integrated medicine of oncology, we have ...
Therapeutic potential of stem c ...
Liver transplantation is the only life-saving procedure for patients with end-stage liver disease. However, its potential benefits are hampered by m ...
Clinical acupuncture research i ...
In recent years, acupuncture has rapidly become part of mainstream medicine in the West, where new developments in acupuncture clinical research show ...
Regulatory factors of mesenchym ...
Adult stem cells hold great promise for wound healing and tissue regeneration. Mesenchymal stem cells (MSCs), for example, have been shown to play a ...