Cause of Chirality Consensus
Nutritional Modulation of Termi ...
Findings with experimental rodent models reveal that exposures to dietary factors during the in utero and pubertal periods when the mammary gland is ...
Ghrelin Regulates Insulin Relea ...
Insulin release from pancreatic islet ..-cells is stimulated by glucose. Glucose-induced insulin release is potentiated or suppressed by hormones and ...
S100A8 and S100A9 Overexpressio ...
S100 protein A8 and A9 naturally form a stable heterocomplex. Recently, we have proved that S100A9 overexpression in various adenocarcinomas is assoc ...
Inflammatory Systemic Biomarker ...
Clinicians have used additional tools to aid clinical assessment and to enhance their ability to identify the “vulnerable” patient at risk for cardio ...
Strategies for Overcoming Inher ...
Mutations in K-Ras are observed in approximately 40% of colon tumours. This has significant implications for predicting likelihood of response to the ...
Recent Methods in Antimalarial ...
As malaria continues to be a worldwide problem due to increasing drug resistance, several drug susceptibility techniques have been reported in the li ...
Natural Non-Trasgenic Animal Mo ...
The most common animal models currently used for Alzheimer disease (AD) research are transgenic mice that express a mutant form of human A.. precurso ...
A New Glucocorticoid Hypothesis ...
The original glucocorticoid (GC) hypothesis of brain aging and Alzheimer’s disease proposed that chronic exposure to GCs promotes hippocampal aging a ...
Optimised electroporation media ...
Background: Immunological therapies enhance the ability of the immune system to recognise and destroy cancer cells via selective killing mechanisms. ...
Cause of Chirality Consensus
Biological macromolecules, proteins and nucleic acids are composed exclusively of chirally pure monomers. The chirality consensus appears vital for l ...
The Pharmacokinetics and Pharma ...
Levodopa , a prodrug of dopamine, remains to be one of the main drugs in the treatment of Parkinson’s disease. All current levodopa products are form ...
Cholinergic Treatment of Trauma ...
In spite of affecting the life of millions of people, chronic traumatic brain injury (TBI) has not been hitherto treatable with effective pharmacolog ...
Liposomal Muramyl Tripeptide Ph ...
About one third of osteosarcoma patients develop lung metastasis refractory to chemotherapy. Recent studies indicate that biological response modifie ...
De Novo and Molecular Target-In ...
There is immediate potential to enhance success and innovation in drug development by pairing newly emerging approaches in medicinal chemistry and co ...
Computational Approaches for Pr ...
A central focus of cancer genetics is the study of mutations that are causally implicated in tumorigenesis. Although missense variants are commonly i ...
Depression and Quality of Life ...
Diabetes patients are known to have a worse quality of life than individuals without diabetes. They also have an increased risk for depressive sympto ...
Ethanol Metabolism and Effects: ...
Ethanol (EtOH) in alcoholic beverages is consumed by a large number of individuals and its elimination is primarily by oxidation. The role of nitric ...
Long-Term Follow-Up of Patients ...
Background: Immunization of patients with Alzheimer’s disease (AD) with synthetic amyloid-.. peptide (A..42) (AN1792) was previously studied in a ran ...
The Role of the COG Database in ...
A major breakthrough in classifying proteins from different microbial genomes in terms of sequence similarity was the development of the COG concept ...
A single dose of DNA vaccine ba ...
Background: Highly pathogenic avian influenza virus subtype H5N1 infects humans with a high fatality rate and has pandemic potential. Vaccination is ...
Atherosclerosis and Arterial Bl ...
Increased blood pressure is a consistent risk factor for the development of atherosclerotic diseases in humans, although the basis for this relations ...
Expression and Function of Krup ...
Krüppel-like factor (KLF) family members share a three C2H2 zinc finger DNA binding domain, and are involved in cell proliferation and differentiatio ...
One Decade Later: What has Gene ...
The many diverse functions executed by the central nervous system (CNS) are mirrored in the diverse shapes, connections, and firing patterns of its i ...
Regulation of the Endoplasmic R ...
Calcium is a ubiquitous second messenger and is involved in virtually all cellular functions. Cellular events being regulated by calcium include gene ...
Mechanisms Used by Human Papill ...
The greatest risk factor for the development of cervical and other cancers that have been linked to the human papillomavirus (HPV) family is the pers ...