Genetics and Molecular Biology of Tuberous Sclerosis Co ...
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Plant Plastid Engineering
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Genetics and Molecular Biology ...
Tuberous Sclerosis Complex is a multisystem disorder exhibiting a wide range of manifestations characterized by tumour-like lesions called hamartomas ...
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MicroRNA: Implications for Alzh ...
Understanding complex diseases such as sporadic Alzheimer disease (AD) has been a major challenge. Unlike the familial forms of AD, the genetic and e ...
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Epigenetic Control of MicroRNA ...
MicroRNAs are a major category among the noncoding RNA fraction that negatively regulate gene expression at the post-transcriptional level, by either ...
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Living without Oxygen: Anoxia-R ...
Many species of marine mollusks demonstrate exceptional capacities for long term survival without oxygen. Analysis of gene expression under anoxic co ...
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Drosophila Lethal Giant Larvae ...
Drosophila lethal giant larvae (lgl) is a tumour suppressor gene whose function in establishing apical-basal cell polarity as well as in exerting pro ...
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Immunobiology of Herpes Simplex ...
Immunologic “immaturity” is often blamed for the increased susceptibility of newborn humans to infection, but the precise mechanisms and details of i ...
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Gene Polymorphisms and Pharmaco ...
Rheumatoid arthritis (RA) is a systemic, chronic and inflammatory disease of unknown etiology with genetic predisposition. The advent of new biologic ...
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How Drosophila melanogaster For ...
A strictly determined number of external sensory organs, macrochaetes, acting as mechanoreceptors, are orderly located on drosophila head and body. T ...
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Host-Cell Survival and Death Du ...
Different Chlamydia trachomatis strains are responsible for prevalent bacterial sexually-transmitted disease and represent the leading cause of preve ...
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Oncogenomic Approaches in Explo ...
Cancer is caused by the spatial and temporal accumulation of alterations in the genome of a given cell. This leads to the deregulation of key signall ...
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Molecular Markers of Tumor Prog ...
Malignant melanoma represents one of the most aggressive malignancies but outcome is highly variable with early tumor lesions having an excellent pro ...
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Mouse Models of Genomic Syndrom ...
Each human's genome is distinguished by extra and missing DNA that can be “benign” or powerfully impact everything from development to disease. In th ...
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3D QSAR Studies of 1,3,4-oxadia ...
Recently several 1,3,4-oxadiazole derivatives were identified as potentially active antimycobacterial agents. Various 5-aryl-2-thio-1,3,4-oxadiazoles ...
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Simultaneous detection of Esche ...
Background: Escherichia coli O157:H7, Vibrio cholerae, and Salmonella typhimurium are pathogenic bacteria found in contaminated water and food. No as ...
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Academia–Industry Collaboration ...
The availability of ،«200 nearly completed genome sequences and >900 additional sequencing projects underway is changing the very fabric of biologi ...
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Genetic Variation and Atheroscl ...
A family history of atherosclerosis is independently associated with an increased incidence of cardiovascular events. The genetic factors underlying ...
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Regulation of Interactions with ...
The molecular machines that replicate the genome consist of many interacting components. Essential to the organization of the replication machinery a ...
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Cause and Consequences of Genet ...
Both genetic and epigenetic changes contribute to development of human cancer. Oncogenomics has primarily focused on understanding the genetic basis ...
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Mass Spectrometry-Based Approac ...
Mass spectrometry has served as a major tool for the discipline of proteomics to catalogue proteins in an unprecedented scale. With chemical and meta ...
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The Biology of Persistent Infec ...
Multiple Sclerosis (MS) is an immune-mediated demyelinating disease of humans. Although causes of MS are enigmatic, underlying elements contributing ...
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Clinical Utility of Microarrays ...
Microarray-based clinical tests have become powerful tools in the diagnosis and treatment of diseases. In contrast to traditional DNA-based tests tha ...
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Signaling Transduction Network ...
Nasopharyngeal carcinoma (NPC) is a polygenetic disease. SPLUNC1, UBAP1, BRD7, NAG7, NOR1, NGX6 and LTF genes were found to be tumor suppressor/susce ...
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Plant Plastid Engineering
Genetic material in plants is distributed into nucleus, plastids and mitochondria. Plastid has a central role of carrying out photosynthesis in plant ...
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Genetic and Molecular Basis of ...
A systematic study has been conducted of all available reports in PubMed and OMIM (Online Mendelian Inheritance in Man) to examine the genetic and mo ...
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Cytosine Methyltransferases as ...
Changes in DNA methylation patterns is a prominent characteristic of human tumors. Tumor cells display reduced levels of genomic DNA methylation and ...
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