Long-term outcome of hemizygous ...
The transcriptional regulator GATA1 is crucially involved in megakaryocytopoiesis and erythropoiesis. Mutations of the gene which is located on the ...
Indoleamine 2,3-dioxygenase in ...
Indoleamine 2,3-dioxygenase (IDO) exerts immunomodulatory effects due to enzymatic activities catalyzing the essential amino acid L-tryptophan. IDO ...
The metalloprotease, NN-PF3 fro ...
NN-PF3 is a non-toxic, anticoagulant, highmolecular- mass (67.81 kDa) metalloprotease from Indian cobra (Naja naja) venom. In the present study, NN- ...
Radiotherapy of solitary plasma ...
Solitary plasmacytoma of the bone (SBP) or extramedullary plasmacytoma (EP) are rare neoplasms amenable to local radiotherapy. In this retrospective ...
Concurrent p16 methylation patt ...
Disruption of cell cycle control genes, including p16, is known to contribute to the cancerogenesis of multiple myeloma (MM). We investigated the me ...
Normal variants of bowel FDG up ...
Objective To evaluate the normal variants of the physiological bowel 2-deoxy-2-[18F]fluoro-D-glucose (FDG) uptake in dual-time-point positron emissi ...
18F-FDG uptake on PET helps pre ...
Background Positron emission tomography (PET) with fluorine-18-fluorodeoxyglucose (18F-FDG) has been studied in thymic epithelial tumors. We evaluat ...
Comparative study of anatomical ...
Objective In single photon emission computed tomography (SPECT) cerebral blood flow studies, two major algorithms are widely used statistical parame ...
Coronary spasm after completion ...
Adenosine is a frequently used pharmacologic stress agent in myocardial perfusion imaging. Its safety profile is well established, and most of its s ...
Glycogen synthase kinase 3 beta ...
The role of glycogen synthase kinase 3 beta (GSK-3b) in modulating Notch control of vascular smooth muscle cell (vSMC) growth (proliferation and apo ...
Mitochondria to nucleus translo ...
Heat shock protein 70 (Hsp70) has been shown to have an anti-apoptotic function, but its mechanism is not clear in heart. In this study, we examined ...
Effect of PAR2 in regulating TN ...
Protease-activated receptor-2 (PAR2) is expressed in endothelial cells and mediates endotheliumdependent vasodilation. We hypothesized that PAR2 reg ...
Clopidogrel improves endothelia ...
Clopidogrel treatment in patients with coronary artery disease not only inhibits platelet activation but also improves endothelial function and nitr ...
Electromechanical effects of th ...
Activation of the atrial renin–angiotensin system plays an important role in the pathophysiology of atrial fibrillation (AF). The pulmonary vein (PV ...
Diffuse large B-cell lymphoma w ...
Cavernous angiomas or hemangiomas and malignant lymphomas rarely involve the cavernous sinus. We report the case of a 72-year-old man with right cir ...
Accuracy of magnetic resonance ...
Dynamic contrast-enhanced breast magnetic resonance (MR) is a promising emerging technique for evaluating breast lesions. A quantitative systematic ...
Detection of circulating tumor ...
Most assays to detect circulating tumor cells (CTCs) rely on EpCAM expression on tumor cells. Recently, our group reported that in contrast to other ...
Transient over-expression of es ...
Estrogen receptor-a (ERa) positive breast cancer frequently responds to inhibitors of ERa activity, such as tamoxifen, and/or to aromatase inhibitor ...
Results of a phase II study of ...
Palliation is the primary goal in metastatic breast cancer (MBC), and safe, efficacious, new singleagent options are needed. Pemetrexed, an antifola ...
Polymorphisms of tumor necrosis ...
We conducted a meta-analysis to assess the association between tumor necrosis factor-alpha (TNFalpha) gene TNFA-308 (G[A), TNFA-238 (G[A), TNFA -85 ...
Joint effect of peroxisome prol ...
Peroxisome proliferator-activated receptor c (PPARc) has been linked with possible antineoplastic effects in colorectal carcinogenesis. However, dat ...
Cognitive function in postmenop ...
Endocrine therapy for breast cancer may affect cognition. The purpose of this study was to examine whether cognitive function improves after cessati ...
Centrosome-related genes, genet ...
Centrosome amplification has been detected in premalignant lesions and in situ tumors in the breast and in over 70%of invasive breast tumors, and ha ...
The non-breast-cancer death rat ...
Non-breast-cancer deaths currently account for almost half of deaths among breast carcinoma patients in the 15 years following diagnosis. Understand ...
Mutation analysis of the SLX4/F ...
SLX4 coordinates three structure-specific endonucleases in the DNA damage response. One subtype of Fanconi anaemia, FA-P, has recently been attribut ...