Where now with NICE?
The National Institute of Clinical Excellence (NICE) is the agency in the UK, charged with the task of appraising Novel Health Technologies. Since i ...
Coordinator-based systems for s ...
The underlying causes of incident fractures— bone fragility and the tendency to fall—remain underdiagnosed and under-treated. This care gap in secon ...
Fitting of bone mineral density ...
Summary A new model describing normal values of bone mineral density in children has been evaluated, which includes not only the traditional paramet ...
Predictors of very low adherenc ...
Summary We developed a clinical prediction rule score to predict medication non-adherence for women prescribed osteoporosis treatment. When combined ...
The impact of substance abuse o ...
Summary Review of the 1-year prevalence of screening for osteoporosis and of osteoporosis or idiopathic fracture in Maryland Medicaid administrative ...
The effect of PTH(1–84) or stro ...
Summary We explored the effects of PTH(1–84) compared with strontium ranelate on bone remodeling as measured by bone remodeling markers in postmenop ...
Smoking is a strong risk factor ...
Summary In this longitudinal study of 4,160 postmenopausal women (3,947 without and 213 with self-reported diabetes), smoking was strongly related t ...
Vertebral fractures in Gaucher ...
Summary Gaucher disease type 1 (GD1), results in a range of skeletal complications including osteopenia, osteoporosis, and osteonecrosis, but there ...
High serum total cholesterol is ...
Summary Risk factors for osteoporotic fractures were evaluated in 1,396 men and women for a period of 20 years. Serum total cholesterol was found to ...
Efficacy of low doses of pamidr ...
Summary This study evaluates the efficacy of low doses of pamidronate after renal transplantation to prevent bone loss in osteopenic patients. Resul ...
Ovariectomy and genes encoding ...
Summary This study investigated the influence of ovarian hormone deficiency on core circadian regulatory protein (CCRP) in the context of bone loss. ...
Serum sclerostin levels positiv ...
Summary Sclerostin is expressed by osteocytes and inhibits bone formation by osteoblasts. In this study, serum sclerostin was positively correlated ...
Multi-site bone ultrasound meas ...
Summary About 75% of patients suffering from osteoporosis are not diagnosed. This study describes a multi-site bone ultrasound method for osteoporos ...
The association between serum o ...
Summary The association between serum osteocalcin levels and metabolic syndrome (MS) in Korean individuals was investigated. Serum osteocalcin level ...
The anti-tumor agent sagopilone ...
Summary Sagopilone, a fully synthetic epothilone and very potent anti-tumor agent, has proved to be efficient in inhibiting bone destruction and tum ...
In peripubertal girls, artistic ...
Summary Peripubertal artistic gymnasts display elevated areal bone mineral density at various bone sites, despite delayed menarche and a high freque ...
Coding Single-Nucleotide Polymo ...
This study aimed to examine whether coding single-nucleotide polymorphisms (cSNPs) of the interleukin- 1 gene cluster [interleukin-1-alpha (IL1a), I ...
Cardiac Troponin T in Children ...
The existence of cardiac damage in active rheumatic carditis patients is unknown, especially in those without pericarditis. The aim of this study wa ...
Benefits of an International Wo ...
This report describes a 1-year exchange between members of two pediatric cardiology centers: one in Canada and one in Australia. Five cardiologists ...
Catabolism of Branched-Chain Am ...
Genetic defects in amino acid metabolism are major causes of newborn diseases that often lead to abnormal development and function of the central ne ...
Novel NKX2-5 Mutations in Patie ...
Atrial septal defect (ASD) is a common cardiovascular malformation and an important contributor to substantial morbidity and mortality. Increasing e ...
Reoperation for a Congenital He ...
A 12-year-old boy was referred for treatment of severe mitral regurge. The boy had already undergone two previous operations. A reduced exercise cap ...
Noncoronary Aortic Cusp Rupture ...
Aortic regurgitation is a common complication of ventricular septal defects. The most common mechanism is right or noncoronary cusp prolapse. Other ...
Partial Occlusion of a Blalock– ...
A 3-month-old male patient was born at 34 weeks’ gestation weighing 1.3 kg with an antenatal diagnosis of severe mitral stenosis, hypoplasia of the ...
Exercise-Induced Myocardial Isc ...
We report a case of anomalous origin of the left main coronary artery (LCA) from the noncoronary sinus of valsalva (LCANCS) in a young healthy patie ...