Decreased expression of EZH2 is ...
The purpose of this study is to investigate EZH2 in a large series of breast cancer patients for its prognostic and predictive value, and to evaluat ...
COX2 expression in prognosis an ...
In breast cancer, the prognostic impact of COX2 expression varies widely between studies. We examined the prognostic value of COX2 expression in a ...
Evaluation of the association o ...
Trastuzumab (T) is effective in metastatic breast cancer (MBC) with HER2 overexpression and/or amplification, but resistance to T develops in a sign ...
Asian ethnicity and breast canc ...
The distribution of breast cancer molecular subtypes has been shown to vary by race/ethnicity, highlighting the importance of host factors in breast ...
Randomized, double-blind compar ...
Near-infrared (NIR) fluorescence imaging has the potential to improve sentinel lymph node (SLN) mapping in breast cancer. Indocyanine green (ICG) is ...
The association between IGF1 CA ...
IGF-I CA repeat polymorphisms have been reported to influence the risk for breast cancer in many studies; however, the results still remains controv ...
Germline mutations in BRCA1 and ...
Three mutations in BRCA1 (185delAG, 5382InsC) and BRCA2 (6174delT) predominate among high risk breast ovarian cancer Ashkenazi Jewish families, with ...
Predictors of non-adherence to ...
The purpose of this study is to investigate 1-year adherence rates to aromatase inhibitors (AI) and to determine risk factors for non-adherence amon ...
Investigating Hardy–Weinberg eq ...
Yu et al. (Breast Cancer Res Treat 117:675–677, 2009) recently stated that testing for deviation from Hardy– Weinberg equilibrium (HWE) is necessary ...
Prognostic significance of micr ...
Maaskant-Braat and colleagues [1] contribute to our understanding of sentinel node micrometastatic disease with this population-based study. Using d ...
Trends in improving survival in ...
In this issue of the Breast Cancer Research and Treatment, there is the encouraging report from van den Hurk et al. [1] that the 5 year overall surv ...
Alcohol consumption and breast ...
Alcohol consumption is known to be a risk factor for breast cancer in Western countries, but few epidemiologic data have been available in Japan. Th ...
Early discontinuation and non-a ...
Despite the benefit of adjuvant hormonal therapy (HT) on mortality among women with breast cancer (BC), many women are non-adherent with its use. We ...
EMSY and CCND1 amplification in ...
EMSY is a putative oncogene amplified in a minority of breast carcinomas, its protein product interacts with and transcriptionally silences BRCA2. W ...
Pathological complete response ...
Sequential doxorubicin/paclitaxel (AT) followed by CMF treatment was shown to be an active neoadjuvant chemotherapy regimen in the first European C ...
Targeted and intracellular trig ...
Limiting tumor invasion to the surrounding healthy tissues has proven to be clinically relevant for anticancer treatment options. We have demonstrat ...
Sleep duration change across br ...
Sleep duration among breast cancer survivors correlates with fatigue, depression, and health-related quality of life (HRQOL); however, this has not ...
Prognostic significance of meth ...
Free circulating DNA is increased in the serum/ plasma of cancer patients, and methylation of certain genes has been found to be characteristic for ...
Role of CD200 expression in reg ...
Previous studies have confirmed that levels of CD200 expression on the cells of the transplantable EMT6 mouse breast cancer line are increased marke ...
High-resolution genomic profili ...
Male breast cancer (MBC) is extremely rare and poorly characterized on the molecular level. Using high-resolution genomic data, we aimed to characte ...
Distinct expressions of microRN ...
Estrogen receptor (ER) a is essential for estrogen-dependent growth, and its level of expression is a crucial determinant of response to endocrine t ...
Alteration of immunohistochemic ...
The immunohistochemical (IHC) biomarkers of breast cancer, especially hormone receptors and HER2, are very important because the pharmacological the ...
Strategy of radiation therapy f ...
Bone metastasis is a common event in advanced cancers such as prostate, breast, lung, and renal cancers. Radiation therapy has been widely used for ...
Radiation therapy for brain met ...
Most randomized comparison trials (RCTs) investigating treatments for brain metastases (BM) have included BM from any origin; as a result, more than ...
A case of metaplastic breast ca ...
Patients with metaplastic breast cancer (MBC) exhibit reduced response to chemotherapy and have poor prognosis. We investigated a case of MBC that s ...