The association between IGF1 CA repeat polymorphisms an ...
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The association between IGF1 CA ...
IGF-I CA repeat polymorphisms have been reported to influence the risk for breast cancer in many studies; however, the results still remains controv ...
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Germline mutations in BRCA1 and ...
Three mutations in BRCA1 (185delAG, 5382InsC) and BRCA2 (6174delT) predominate among high risk breast ovarian cancer Ashkenazi Jewish families, with ...
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Improved survival of patients w ...
In this study, changes in prognosis for more than 8,000 patients with primary distant metastatic breast cancer were analyzed, using nation-wide data ...
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Predictors of non-adherence to ...
The purpose of this study is to investigate 1-year adherence rates to aromatase inhibitors (AI) and to determine risk factors for non-adherence amon ...
208.63 KB
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Investigating Hardy–Weinberg eq ...
Yu et al. (Breast Cancer Res Treat 117:675–677, 2009) recently stated that testing for deviation from Hardy– Weinberg equilibrium (HWE) is necessary ...
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Prognostic significance of micr ...
Maaskant-Braat and colleagues [1] contribute to our understanding of sentinel node micrometastatic disease with this population-based study. Using d ...
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The CYP17A1 234T > C polymor ...
Exposure to estrogen has a major effect on breast cancer risk. A polymorphism (-34 T[C; rs743572) in the cytochrome P450c17alpha gene (CYP17A1) enc ...
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Early discontinuation and non-a ...
Despite the benefit of adjuvant hormonal therapy (HT) on mortality among women with breast cancer (BC), many women are non-adherent with its use. We ...
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Individual responses to chemoth ...
Differences in redox homeostatic control between cancer patients may underlie predisposition to drug resistance and toxicities. To evaluate interind ...
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No evidence for an association ...
Breast cancer represents a serious public health problem worldwide, for its high incidence, morbidity, mortality, and its high cost treatment. It is ...
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Replication of genome-wide disc ...
Genome-wide association studies (GWAS) have identified associations with robust statistical support for influencing breast cancer susceptibility. Mo ...
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A high prevalence of BRCA1 muta ...
The Bahamas is a group of islands in the Caribbean with a high incidence of early onset breast cancer. In isolated populations, the identification o ...
185.69 KB
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High estrogen receptor expressi ...
One of the most controversial questions in early breast cancer treatment is the need of chemotherapy in patients with estrogen receptor positive dis ...
404.08 KB
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Molecular and epidemiological c ...
Inflammatory breast cancer (IBC) shows a high incidence in Tunisia and Egypt but epidemiological and molecular characteristics have not been describ ...
216.30 KB
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Metabotropic glutamate receptor ...
Metabotropic glutamate receptors are G-protein- coupled receptors normally expressed in the central nervous system where they mediate neuronal excit ...
506.90 KB
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Gene expression profile testing ...
As gene expression profile (GEP) testing for breast cancer may provide additional prognostic information to guide the use of adjuvant chemotherapy, ...
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Prognostic significance of meth ...
Free circulating DNA is increased in the serum/ plasma of cancer patients, and methylation of certain genes has been found to be characteristic for ...
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High-resolution genomic profili ...
Male breast cancer (MBC) is extremely rare and poorly characterized on the molecular level. Using high-resolution genomic data, we aimed to characte ...
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The role of topoisomerase IIa i ...
Topoisomerase IIa is not only a proliferation marker of tumor cells, but is also a target for anthracyclinebased chemotherapy. Both in vitro and in ...
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Pathological characteristics of ...
The immunophenotype of BRCA-associated breast cancer has been studied in predominantly non-Hispanic whites (NHW). We evaluated the pathological char ...
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Distinct expressions of microRN ...
Estrogen receptor (ER) a is essential for estrogen-dependent growth, and its level of expression is a crucial determinant of response to endocrine t ...
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Refractory lung metastasis from ...
suggestive case of metastatic disease from breast cancer is reported. The HER-2-positive tumor was refractory to several agents, including anti-HER- ...
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Strategy of radiation therapy f ...
Bone metastasis is a common event in advanced cancers such as prostate, breast, lung, and renal cancers. Radiation therapy has been widely used for ...
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Radiation therapy for brain met ...
Most randomized comparison trials (RCTs) investigating treatments for brain metastases (BM) have included BM from any origin; as a result, more than ...
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Lung Tumor Radiofrequency Ablat ...
Today, radiofrequency ablation (RFA) of primary and metastatic lung tumor is increasingly used. Because RFA is most often used with curative intent, ...
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