Update on the Management of Pediatric Chronic Hepatitis ...
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Update on the Management of Ped ...
A primary challenge in the management of pediatric chronic hepatitis B (CHB) is the lack of established child-specific guidelines. Treatment decisio ...
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New and Evolving Management Par ...
Hepatitis-C induced liver failure is the leading indication for liver transplantation in the United States, and the burden of hepatitis C virus (HCV ...
2.74 MB
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Update on the Risk of Hepatocel ...
Chronic hepatitis B virus infection is an important cause of liver-related morbidity and mortality, with hepatocellular carcinoma being the most lif ...
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Combination Therapy for Chronic ...
Hepatitis B infection remains a major public health problem globally and in the United States, with significant use of healthcare resources. Several ...
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Ribavirin: How Does it Work and ...
Ribavirin is a synthetic guanosine analogue, which acts against hepatitis C virus (HCV) through several mechanisms that include 1) immune modulation ...
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Hepatitis B Genotypes: Role of ...
Hepatitis B viral genotypes influence natural history, with genotype Cmore likely to develop hepatocellular carcinoma than genotype B, thus influenc ...
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IL28B Polymorphisms as a Predic ...
Hepatitis C virus (HCV) is the most common cause of chronic liver disease in the United States. There are more than 170 million cases worldwide, and ...
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IL28B: Implications for Therapy
Within the last 2 years, a number of Genome- Wide Association Studies (GWAS) have shown that single nucleotide polymorphisms (SNPs) in the interleuk ...
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Management of Lower-Risk Myelod ...
Myelodysplastic syndromes (MDS) represent a spectrum of bone marrow failure with variable outcome. Patients with “lower-risk” disease have an expect ...
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The Relevance of Iron Overload ...
Accumulation of excessive amounts of iron in vulnerable organs and tissues, together with elevated plasma and intracellular concentrations of reacti ...
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Updates in Cytogenetics and Mol ...
Myelodysplastic syndromes (MDS) are clonal hematologic neoplasms that can result in cytopenias and increase the risk of leukemic transformation. The ...
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What is the Best Frontline Ther ...
Chronic lymphocytic leukemia (CLL) is a lymphoproliferative disease with significant variation in disease progression, response to therapy, and surv ...
257.46 KB
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Late Effects of Childhood Leuke ...
As survival rates for children treated for childhood cancers become significantly better, the focus is increasingly on determining the late effects ...
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Treatment of Newly Diagnosed My ...
Melphalan plus prednisone (MP) has long been considered the gold-standard treatment for elderly patients with newly diagnosed myeloma, and it still ...
136.64 KB
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Role of Tyrosine Kinase Inhibit ...
The Philadelphia chromosome is the most common cytogenetic abnormality found in adult patients diagnosed with acute lymphoblastic leukemia. The resu ...
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Treatment of Newly Diagnosed Mu ...
Treatment of myeloma has changed significantly in the past decade as a result of better understanding of disease biology, more effective treatments, ...
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New Drugs for Chronic Myelogeno ...
The introduction of tyrosine kinase inhibitors (TKIs) has changed the landscape of therapy for chronic myelogenous leukemia (CML). Once considered a ...
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Can Low-Risk, Early-Stage Patie ...
Advances in the treatment of Hodgkin lymphoma since about 1970 have led to a remarkable improvement in the long-term outcomes of what was once cons ...
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Predicting the Response of CML ...
As of 2011, the choice of tyrosine kinase inhibitor (TKI) for the patient with newly diagnosed chronic-phase chronic myelogenous leukemia (CP-CML) ...
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The Role of Autologous Transpla ...
Between 80% and 90% of Hodgkin lymphoma (HL) patients can be cured with up-to-date combinedmodality treatments, but patients with disease refractory ...
258.27 KB
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In Search of CML Stem Cells’ De ...
Chronic myeloid leukemia (CML) is a clonal myeloproliferative disorder that is characterized by the presence of a fusion oncogene, BCR-ABL, which en ...
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The Unique Characteristics and ...
In recent decades, the prognosis of Hodgkin lymphoma has been substantially improved, but these successes have been restricted to younger patients a ...
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Chronic Myelogenous Leukemia: M ...
Molecular monitoring is a key component of the management of patients with chronic myeloid leukemia. The current recommendation is that molecular mo ...
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Primary Mediastinal Large B-Cel ...
In recent years, an overlap in biologic and clinical features has been identified between classic Hodgkin lymphoma (CHL) and primary mediastinal lar ...
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Impact of Diabetes on Postinfar ...
Diabetes mellitus, the metabolic syndrome, and the underlying insulin resistance are increasingly associated with diastolic dysfunction and reduced ...
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