Digital image analysis of membrane connectivity is a ro ...
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Digital image analysis of membr ...
The purpose of this study was to develop and validate a new software, HER2-CONNECTTM, for digital image analysis of the human epidermal growth facto ...
1.89 MB
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Evidence for a link between TNF ...
Intracellular signaling mediated by the receptor activator of nuclear factor-jB [Rank, encoded by the tumor necrosis factor receptor superfamily, me ...
350.51 KB
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ErbB1/2 tyrosine kinase inhibit ...
Overexpression of epidermal growth factor receptors (ErbB) is frequently seen in inflammatory breast cancer (IBC). Treatment with ErbB1/2-targeting ...
563.27 KB
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Keratin 15, transcobalamin I an ...
Breast phyllodes tumors are rare neoplasms which present challenges for histological classification. Microscopic features are not always predictive ...
649.44 KB
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Prognostic value of acquired un ...
Many studies have examined DNA copy number changes or gene expression profiling and their association with clinical outcomes in breast cancer. Howev ...
268.12 KB
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Effect of false-positives and w ...
False-positive results may influence adherence to mammography screening. The effectiveness of breast cancer screening is closely related to adequate ...
304.26 KB
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Pilot and feasibility study: pr ...
Normal mammary gland homeostasis requires the coordinated regulation of protein signaling networks. However, we have little prospective information ...
746.01 KB
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First-line bevacizumab in combi ...
Despite extensive evaluation of first-line bevacizumab- containing therapy in randomized trials in locally recurrent/metastatic breast cancer (LR/mB ...
325.02 KB
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Androgens and musculoskeletal s ...
Aromatase inhibitors (AIs), the adjuvant hormonal treatment of choice for postmenopausal estrogen receptor-positive breast cancer, are associated wi ...
374.87 KB
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The prognostic significance of ...
Although the favourable role of T lymphocyte populations in different tumour types is established, that of B cells is still a matter of debate and n ...
767.00 KB
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Targeting low molecular weight ...
Low molecular weight cyclin E (LMW-E) plays an important oncogenic role in breast cancer. LMWE, which is not found in normal tissue, can promote the ...
979.45 KB
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Elevated PCNA+ tumor-associated ...
African American and Hispanic women develop more triple negative breast cancer at younger ages than Caucasian women. The frequently observed associa ...
561.56 KB
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Childhood factors associated wi ...
Growth and development factors could contribute to the development of breast cancer associated with an increase in mammographic density. This study ...
217.56 KB
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Aberrant DNA methylation but no ...
CBP/p300-interacting transactivator with EDrich carboxy-terminal domain 4 (CITED4) inhibits HIF-1a transactivation by binding to CBP/p300. We hypoth ...
912.42 KB
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Combined effects of MDM2 SNP309 ...
The MDM2 oncoprotein regulates the p53 pathway and, while functional polymorphisms of the MDM2 and p53 genes have been investigated for association ...
237.00 KB
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Glucocorticoid receptor activit ...
The purpose of this article is to determine the tumorigenic potential of estradiol treatment (E2) when combined with either progesterone (P4) or med ...
1.27 MB
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Excised and irradiated volumes ...
In early-stage breast cancer and DCIS patients, breast-conserving therapy is today’s standard of care. The purpose of this study was to evaluate the ...
425.71 KB
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Tamoxifen metabolites as active ...
The mechanism of tamoxifen action in the treatment of breast cancer is believed to be via active metabolites that act as potent estrogen receptor an ...
329.43 KB
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Understanding of the immunologi ...
We have evaluated the phenotypic features of peripheral blood leukocytes as putative novel biomarkers with prognostic values to monitor canine mamma ...
694.97 KB
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The chemokine receptor CCR4 pro ...
Increasing evidence has shown that chemokines and chemokine receptors are associated with tumor growth and metastasis. CCR4, an important chemokine ...
740.46 KB
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The association between chronic ...
Greater chronic disease burden may decrease quality of life (QOL) of breast cancer survivors. Our objective was to investigate the association betwe ...
232.50 KB
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Prolonged mammosphere culture o ...
Mammosphere culture has been used widely for the enrichment of mammary epithelial stem cells and breast cancer stem cells (CSCs). Epithelial-to-mese ...
829.15 KB
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Multivitamin use and breast can ...
Little is known about the relation of multivitamin use to breast cancer outcomes. 2,236 women diagnosed from 1997 to 2000 with early-stage breast ca ...
223.10 KB
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Effect of primary prophylactic ...
Effective systemic therapy is vital for successful breast cancer treatment, but early onset toxicities like neutropenia hinder systemic therapy admi ...
220.23 KB
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Pathological characteristics of ...
The immunophenotype of BRCA-associated breast cancer has been studied in predominantly non-Hispanic whites (NHW). We evaluated the pathological char ...
242.94 KB
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