Age-specific trends of survival in metastatic breast ca ...
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Age-specific trends of survival ...
Treatment of metastatic breast cancer (MBC) has evolved during the last decades but it is largely unknown whether this has led to improved survival ...
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First generation prognostic gen ...
The aims of this study were to compare the performance of six different genomic prognostic markers to predict long-term survival and chemotherapy re ...
296.20 KB
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The role of topoisomerase IIa i ...
Topoisomerase IIa is not only a proliferation marker of tumor cells, but is also a target for anthracyclinebased chemotherapy. Both in vitro and in ...
597.94 KB
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Androgen receptor expression in ...
The androgen receptor (AR) has been shown to be of potential prognostic importance in retrospective cohorts. We evaluated immunohistochemical AR exp ...
633.43 KB
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LMTK3 expression in breast canc ...
Interactions between kinases and the estrogen receptor a (ERa) are thought to be a critical signaling pathway in the majority of human breast cancer ...
450.90 KB
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Biopsy sampling of breast lesio ...
Needle biopsy is now the initial investigation of choice for the pre-operative diagnosis of breast lesions. This includes core needle biopsy (CNB) a ...
184.95 KB
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COX-2 expression predicts worse ...
Some previous studies have found worse prognosis among cyclooxygenase-2 (COX-2)-expressing breast cancers. Aspirin and NSAIDs inhibit COX-2. Three ...
282.22 KB
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Predictive value of BI-RADS cla ...
In this study, we assessed the positive-predictive value (PPV) of mammography and/or ultrasonography in women age 50 based on recommendations for bi ...
170.50 KB
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Variation in breast cancer risk ...
Germline mutations in BRCA1/2 confer a high risk of breast cancer (BC), but the magnitude of this risk varies according to various factors. Although ...
414.64 KB
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Leptomeningeal metastases from ...
Leptomeningeal metastasis (LM) usually occurs late during the course of breast cancer. The aim of this study was to characterize the clinical featur ...
346.82 KB
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Epithelial-mesenchymal transiti ...
Currently used methods to detect and enumerate circulating tumor cells (CTCs) rely on the expression of the epithelial cell adhesion molecule (EpCAM ...
261.29 KB
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Unliganded progesterone recepto ...
Whether the presence of steroid receptors in luminal breast cancers renders them resistant to taxanes remains uncertain. Here we assess the role of ...
730.96 KB
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Immunohistochemically defined s ...
The aim of this study is to evaluate the outcome of occult breast cancer (OBC) in patients with axillary presentation overall and according to the i ...
257.23 KB
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Protective effect of longstandi ...
Reproductive risk factors and associated risk for breast cancer have been and remain the subject of intense investigation. Particular attention is g ...
152.82 KB
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Inhibitors of histone demethyla ...
Abnormal activities of histone lysine demethylases (KDMs) and lysine deacetylases (HDACs) are associated with aberrant gene expression in breast can ...
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Specific kinesin expression pro ...
Breast cancer is a genetically heterogenous disease with subtypes differing in prognosis and chemosensitivity. The basal-like breast cancer (BLBC) m ...
551.99 KB
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Genetic variation in proinflamm ...
Proinflammatory cytokines are associated with age-related diseases including arthritis and heart disease. IL6 and TNF also play key roles in estroge ...
209.70 KB
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Patient and tumor characteristi ...
Few data are available on bilateral breast cancer in the screening population. The aim of this study was to determine patient and tumor characterist ...
188.66 KB
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Genotypes and phenotypes of IGF ...
The relationship between IGF genotypes and phenotypes in breast tumors and their associations with breast cancer risk remain to be elucidated. Such ...
244.88 KB
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Mesenchymal stem cells from pri ...
Mesenchymal stem cells (MSCs) play a critical role in promoting cancer progression. However, it is not clear whether MSCs are located in breast canc ...
1.24 MB
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Breast cancer risk assessment i ...
Although the benefit of screening mammography for women over 69 has not been established, it is generally agreed that screening recommendations for ...
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221.79 KB
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The earwax-associated SNP c.538 ...
Genetic polymorphisms of human ABC-transporter genes have been suggested to modulate breast cancer risk in the general population. In particular ABC ...
197.63 KB
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The impact of obesity on receip ...
Disparities in the receipt of adjuvant chemotherapy for early stage breast cancer is an important factor influencing mortality. We investigated whet ...
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Physical activity and breast ca ...
The study was conducted to determine the effect of physical activity on DNA methylation and to predict the consequence of this effect concerning gen ...
290.16 KB
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Co-amplification of the HER2 ge ...
Co-amplification of the centromere on chromosome 17 (CEP17) and HER2 can occur in breast cancer. Such aberrant patterns (clusters) on CEP17 can be m ...
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