Correlation of breast cancer susceptibility loci with p ...
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Correlation of breast cancer su ...
To understand the biology of low-risk breast cancer alleles, and to investigate whether these loci also contribute to disease progression that was o ...
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Frondoside A inhibits breast ca ...
Frondoside A, derived from the sea cucumber Cucumaria frondosa has demonstrable anticancer activity in several models, however, the ability of Frond ...
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Lack of efficacy to systemic ch ...
Metaplastic carcinoma of the breast (MCB) is a rare subtype of breast cancer. Anecdotal reports are available regarding its response to systemic che ...
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Addition of a histone deacetyla ...
Modulation of estrogen signaling is one of the most successful modalities for the treatment of estrogen receptor (ER)-positive breast cancer, yet de ...
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Cancer predisposing BARD1 mutat ...
The breast cancer susceptibility gene BARD1 (BRCA1-associated RING domain protein, MIM# 601593) acts with BRCA1 in DNA double-strand break (DSB) re ...
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Behavioral risk factors and the ...
Hispanics are more likely to be diagnosed with breast cancer at a younger age, with more advanced stage at diagnosis, hormone receptor-negative tumo ...
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The p160 ER co-regulators predi ...
The SRC family of ER co-regulators are frequently overexpressed in breast cancer. Overexpression of AIB1 appears to be linked to hormone resistance ...
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bc-GenExMiner: an easy-to-use o ...
Gene prognostic meta-analyses should benefit from breast tumour genomic data obtained during the last decade. The aim was to develop a user-friendly ...
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Primary tumor classification ac ...
Breast cancer patients with similar clinical stage may experience different disease outcomes. Aberrant DNA methylation of primary breast tumors can ...
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Genetic variants of 6q25 and br ...
A recent genome-wide association study identified a novel single nucleotide polymorphism (SNP), rs2046210, in the 6q25 region as a breast cancer sus ...
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Prevalence of BRCA1/2 mutations ...
In order to adequately evaluate the clinical relevance of genetic testing in sporadic breast and ovarian cancer patients, we offered comprehensive B ...
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Two new CHEK2 germ-line variant ...
CHEK2 gene mutations occur in a subset of patients with familial breast cancer, acting as moderate/low penetrance cancer susceptibility alleles. Alt ...
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Detection of isolated ipsilater ...
Imaging diagnostic methods except for mammograms are not recommended for follow-up of postoperative breast cancer patients in order to detect small ...
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Association between the p53 pol ...
p53 is a tumor suppressor gene and plays an important role in the etiology of breast cancer. However, studies on the association between p53 polymor ...
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Single nucleotide polymorphisms ...
The 20q13 region is frequently amplified/overexpressed in breast tumours. However, the nature of this amplification/overexpression is unknown. Here, ...
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Long-term course of pain in bre ...
After successful treatment of early breast cancer, many women still report pain symptoms, and attribute them to the previous illness or its treatmen ...
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RAD50 and NBS1 are not likely t ...
Deleterious mutations in several genes that are involved in repair of damage to DNA have been associated with an increased risk of breast cancer. Re ...
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A retrospective study of breast ...
Immunohistochemical markers are often used to classify breast cancer into subtypes that are biologically distinct and behave differently. The aim of ...
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Prognosis of metachronous contr ...
Studies comparing the prognosis after contralateral breast cancer (CBC) with that after unilateral breast cancer (UBC) shows conflicting results. We ...
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HER2 discordance between primar ...
The proto-oncogene, HER2, has prognostic and predictive relevance in invasive breast cancer (IBC). HER2 testing of primary IBC guides treatment sele ...
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Comparative gene expression ana ...
Functional development of the mammary gland is an important physiological process. Several studies have used gene expression profiling of mammary gl ...
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Insulin-like growth factor-1 re ...
Insulin-like growth factor-1 receptor (IGF1R) plays a key role in the initiation and progression of breast cancer. However, its prognostic relevance ...
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Identification of a new complex ...
In this study, we present a novel complex rearrangement in the BRCA1 gene. The genomic rearrangement was identified using one of the two commerciall ...
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A phase II neoadjuvant trial of ...
Endocrine therapy in patients with breast cancer can be limited by the problem of resistance. Preclinical studies suggest that complete blockade of ...
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Gene expression profiling of lu ...
The luminalBsubtype represents a group of high proliferating estrogen receptor positive breast cancers which are associated with a poor prognosis. G ...
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