Hematogenous and lymphatic tumor cell dissemination may ...
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Hematogenous and lymphatic tumo ...
Tumor cell dissemination in bone marrow (BM) and lymph nodes is considered an important step in systemic disease progression and is associated with ...
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FOXA1 is an independent prognos ...
Forkhead box protein A1 (FOXA1) is a ‘‘pioneer factor’’ that plays a role in controlling nearly 50% of estrogen receptor target genes. FOXA1 express ...
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COX2 overexpression is a progno ...
To determine the significance of (Cyclooxygenase 2) COX2 for clinical outcome in breast cancer, we analyzed the correlation between COX2 overexpress ...
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Overexpression of ligase defect ...
E6-associated protein (E6-AP) is a dual function protein. It acts as an E3 ubiquitin-protein ligase enzyme and coactivator of steroid hormone recept ...
1.36 MB
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Absenteeism and short-term disa ...
Few data exist related to the impact of breast cancer on work absenteeism and short-term disability. This retrospective study estimated the extent a ...
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Transcriptomic and proteomic pr ...
Sulforaphane (SFN), an isothiocyanate found in cruciferous vegetables, is a potent inhibitor of experimental mammary carcinogenesis and may be an ef ...
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Prevalence and characterization ...
Although there are some studies to investigate germline mutations in BRCA1/2 genes in Chinese women with familial breast cancer, many of them suffer ...
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Characterisation of unclassifie ...
subset of the unclassified variants (UVs) identified during genetic screening of BRCA1/2 genes may affect splicing. We assessed at RNA level the eff ...
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A prognostic model for lymph no ...
model for a more precise prognosis of the risk of relapse is needed to avoid overtreatment of lymph node-negative breast cancer patients. A large de ...
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Identification of the receptor ...
The identification of molecular features that contribute to the progression of breast cancer can provide valuable insight into the pathogenesis of t ...
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Predictors of timing of adjuvan ...
Adherence to consensus guidelines for cancer care may vary widely across health care settings and contribute to differences in cancer outcomes. For ...
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Gene expression profile testing ...
As gene expression profile (GEP) testing for breast cancer may provide additional prognostic information to guide the use of adjuvant chemotherapy, ...
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Different CHEK2 germline mutati ...
Germline mutations in BRCA1 were already linked to basal-like subtype of immunophenotypic molecular classification of breast cancer (BC). However, i ...
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A SEER-Medicare population-base ...
Each year there are an estimated 200,000 new breast cancer cases diagnosed in the United States; of these, 1% of cases are in men. Lymphedema can be ...
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Common genetic polymorphisms of ...
Recent compelling evidence indicates that mutation, aberrant expression, and dysregulation of microRNA (miRNA) biogenesis are implicated in cancer ...
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Co-expression of SNAIL and TWIS ...
Epithelial mesenchymal transition (EMT) plays an important role in the development of metastases. One of the hallmarks of EMT is loss of E-cadherin ...
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b-Adrenergic receptors (b-AR) r ...
Activation of b-adrenergic receptors (b-AR) drives proangiogenic factor production in several types of cancers. To examine b-AR regulation of breast ...
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The prognostic role of circulat ...
The prognostic significance of circulating tumor cells (CTCs) in patients with breast cancer is controversial. We performed a meta-analysis of publi ...
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Traditional breast cancer risk ...
At least four major categories of invasive breast cancer have been reproducibly identified by gene expression profiling: luminal A, luminal B, HER2- ...
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Loss of Yes-associated protein ...
Yes-associated protein (YAP) is a well characterized transcriptional coactivator that interacts with various transcription factors and modulates the ...
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FOXC1, a target of polycomb, in ...
Polycomb group (PcG) proteins have recently been shown related to cancer development. The PcG protein EZH2 is involved in progression of prostate an ...
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KX-01, a novel Src kinase inhib ...
KX-01 is the first clinical Src inhibitor of the novel peptidomimetic class that targets the peptide substrate site of Src providing more specificit ...
1.53 MB
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Second events following ductal ...
The incidence of ductal carcinoma in situ (DCIS) of the breast has increased in recent decades, particularly, in counties offering mammography scree ...
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Correlates of fear of cancer re ...
Fear of cancer recurrence (FCR) is a common and persistent concern among breast cancer survivors. Little is known about factors associated with FCR ...
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Sleep duration change across br ...
Sleep duration among breast cancer survivors correlates with fatigue, depression, and health-related quality of life (HRQOL); however, this has not ...
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