Associations between polymorphisms of tumor necrosis fa ...
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Associations between polymorphi ...
We read with great interest the article by Yang et al. which investigated the associations between tumor necrosis factor-a (TNF-a) polymorphisms an ...
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Increased risk for distant meta ...
The identification of women with early-stage breast cancer who will develop distant metastasis may improve clinical management. The transcriptional ...
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Association between polymorphis ...
The renin–angiotensin system (RAS) has been considered to be implicated in the development of breast cancer. However, the results are inconsistent. ...
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ER, HER2, and TOP2A expression ...
At recurrence of breast cancer, the therapeutic target is the metastases. However, it is current practice to base the choice of systemic treatment o ...
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Elimination of the chemotherapy ...
Metastatic breast cancer is currently incurable despite initial responsiveness, assumingly due to the presence of chemoresistant subpopulations that ...
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Circulating free DNA: a new sur ...
Despite progress made in the oncologic therapy, the prognosis of the patients with breast cancer is still limited by metastatic relapse often many y ...
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The tamoxifen metabolite norend ...
To improve the treatment of breast cancer, there has been a need for alternative aromatase inhibitors (AIs) that bring about adequate aromatase inhi ...
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Five-year patterns of adjuvant ...
Adjuvant hormonal therapy (HT) for breast cancer improves survival, yet studies have shown that early discontinuation and suboptimal adherence are c ...
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Metabotropic glutamate receptor ...
Metabotropic glutamate receptors are G-protein- coupled receptors normally expressed in the central nervous system where they mediate neuronal excit ...
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MDM2 SNP309 and TP53 R72P assoc ...
The aim of this study was to investigate the association of two genetic polymorphisms, MDM2 SNP309 and TP53 R72P, with incidence of neutropenia in b ...
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The effect of delays in treatme ...
It is generally accepted that delay in receiving treatment for breast cancer results in adverse outcomes. The purpose of this study was to evaluate ...
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Genetic predictors of taxane-in ...
Taxanes have resulted in improved survival for breast cancer patients, but often cause neurological toxicities. Identification of biomarkers related ...
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Locally advanced breast cancers ...
Interval cancers (ICs), defined as cancers detected between regular screening mammograms, have been shown to be of higher grade, larger size, and as ...
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Membrane localization of insuli ...
Recent studies have identified a role for insulin receptor substrate-2 (IRS-2) in promoting motility and metastasis in breast cancer. However, no pu ...
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Differential expression of arre ...
Emerging evidence has implicated G proteincoupled receptors, such as CXCR4 and PAR2, in breast cancer progression and the development of metastatic ...
1.30 MB
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Molecular and epidemiological c ...
Inflammatory breast cancer (IBC) shows a high incidence in Tunisia and Egypt but epidemiological and molecular characteristics have not been describ ...
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Final overall survival results ...
The ATHENA study expanded on the safety and efficacy data derived from first-line trials of bevacizumab combined with standard chemotherapy for loc ...
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Deoxycytidine kinase is overexp ...
Only a minority of breast cancer patients responds to chemotherapy and we lack predictive biomarkers that help to select a patient-tailored therapy ...
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Daintain/AIF-1 promotes breast ...
Tumor-associated macrophages can release a vast diversity of growth factors, proteolytic enzymes, cytokines, and inflammatory mediators. Many of the ...
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Well-done meat intake and meat- ...
Previous studies of the association of meat intake and meat-derived mutagen exposure with breast cancer risk have produced inconsistent results. We ...
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The association of reproductive ...
Reproductive factors that influence breast cancer risk may also have an impact on survival, once the disease is diagnosed. In this study, 2,640 wome ...
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The influence of removal of pri ...
Recent studies have shown that the detection of circulating tumor cells (CTC) pre and postoperatively in the peripheral blood of primary breast canc ...
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Mothers’ pre-pregnancy BMI and ...
Previous studies have established that higher birthweight is associated with increased risk of breast cancer. However, the mechanisms underlying thi ...
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Lack of association between hOG ...
Recently, we read with great interest the article ‘‘The hOGG1 Ser326Cys polymorphism and breast cancer risk: a meta-analysis’’ published online in A ...
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In situ detection of HER2:HER2 ...
HER2 overexpression/amplification is linked with poor prognosis in early breast cancer. Co-expression of HER2 and HER3 is associated with endocrine ...
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