Regulation of Interactions with Sliding Clamps During D ...
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Regulation of Interactions with ...
The molecular machines that replicate the genome consist of many interacting components. Essential to the organization of the replication machinery a ...
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Simultaneous detection of Esche ...
Background: Escherichia coli O157:H7, Vibrio cholerae, and Salmonella typhimurium are pathogenic bacteria found in contaminated water and food. No as ...
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3D QSAR Studies of 1,3,4-oxadia ...
Recently several 1,3,4-oxadiazole derivatives were identified as potentially active antimycobacterial agents. Various 5-aryl-2-thio-1,3,4-oxadiazoles ...
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Mouse Models of Genomic Syndrom ...
Each human's genome is distinguished by extra and missing DNA that can be “benign” or powerfully impact everything from development to disease. In th ...
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Molecular Markers of Tumor Prog ...
Malignant melanoma represents one of the most aggressive malignancies but outcome is highly variable with early tumor lesions having an excellent pro ...
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Living without Oxygen: Anoxia-R ...
Many species of marine mollusks demonstrate exceptional capacities for long term survival without oxygen. Analysis of gene expression under anoxic co ...
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Epigenetic Control of MicroRNA ...
MicroRNAs are a major category among the noncoding RNA fraction that negatively regulate gene expression at the post-transcriptional level, by either ...
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MicroRNA: Implications for Alzh ...
Understanding complex diseases such as sporadic Alzheimer disease (AD) has been a major challenge. Unlike the familial forms of AD, the genetic and e ...
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Beyond Stressed Self: Evidence ...
The activity of cytotoxic lymphocytes is regulated by the opposing function of stimulatory and inhibitory cell surface receptors. According to the no ...
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Estrogen Regulation of MicroRNA ...
Women outlive men, but life expectancy is not influenced by hormone replacement (estrogen + progestin) therapy. Estrogens appear to protect brain, ca ...
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Rallying the Troops: Innate Muc ...
The mucosal surfaces of the gastrointestinal tract are constantly exposed to large quantities of commensal microbes and enteric pathogens. Highly sop ...
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Dendritic Cells and Macrophages ...
Dendritic cells (DCs) and macrophages differently contribute to the generation of coordinated immune system responses against infectious agents. They ...
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The Arrestin Fold: Variations o ...
Endocytosis of ligand-activated plasma membrane receptors has been shown to contribute to the regulation of their downstream signaling. ..-arrestins ...
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Implication of CD154/CD40 Inter ...
The discovery of new functions for CD154 and CD40 molecules has expanded our knowledge to claim that CD154 plays well beyond its postulated role in a ...
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The Story of SPATA2 (Spermatoge ...
In an attempt to isolate new spermatogenesis-associated genes, pd1 was initially identified and cloned as a novel human cDNA sequence from testis cDN ...
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One Decade Later: What has Gene ...
The many diverse functions executed by the central nervous system (CNS) are mirrored in the diverse shapes, connections, and firing patterns of its i ...
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Expression and Function of Krup ...
Krüppel-like factor (KLF) family members share a three C2H2 zinc finger DNA binding domain, and are involved in cell proliferation and differentiatio ...
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Long-Term Follow-Up of Patients ...
Background: Immunization of patients with Alzheimer’s disease (AD) with synthetic amyloid-.. peptide (A..42) (AN1792) was previously studied in a ran ...
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Depression and Quality of Life ...
Diabetes patients are known to have a worse quality of life than individuals without diabetes. They also have an increased risk for depressive sympto ...
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Natural Non-Trasgenic Animal Mo ...
The most common animal models currently used for Alzheimer disease (AD) research are transgenic mice that express a mutant form of human A.. precurso ...
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Inflammatory Systemic Biomarker ...
Clinicians have used additional tools to aid clinical assessment and to enhance their ability to identify the “vulnerable” patient at risk for cardio ...
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Towards Retinoid Therapy for Al ...
Alzheimer’s disease(AD) is associated with a variety of pathophysiological features, including amyloid plaques, inflammation, immunological changes, ...
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Anti-Apoptotic Genes in the Sur ...
Macrophages are cells of the immune system that protect organisms against invading pathogens by fulfilling critical roles in innate and adaptive immu ...
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CENPA a Genomic Marker for Cent ...
Inheritance of genetic material requires that chromosomes segregate faithfully during cell division. Failure in this process can drive to aneuploidy ...
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Signal Processing for Metagenom ...
Traditionally, studies in microbial genomics have focused on single-genomes from cultured species, thereby limiting their focus to the small percenta ...
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