MicroRNA-30c expression level is an independent predict ...
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MicroRNA-30c expression level i ...
MicroRNAs (miRNAs) are small RNA molecules that modulate gene expression and which have been implicated in cancer. We evaluated whether five candida ...
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Biological and clinical implica ...
Nicastrin is an essential component of the gamma secretase (GS) enzyme complex, required for its synthesis and recognition of substrates for proteol ...
1.26 MB
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CTEN (C-terminal tensin-like), ...
C-terminal tensin-like (CTEN) gene is a member of the TENSIN gene family, involved in cell migration and localised at focal adhesion sites. This stu ...
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MPA-induced gene expression and ...
Over the past several years, we have been interested in understanding the mechanisms by which mammary carcinomas acquire hormone independence. We d ...
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Mediator of DNA damage checkpoi ...
The mediator of DNA damage checkpoint protein 1 (MDC1) regulates cell cycle checkpoints and recruits repair proteins to sites of double-stranded DNA ...
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Native MAG-1 antibody almost de ...
native form of mouse monoclonal IgG1 antibody called MAG-1, which recognizes an epitope on provasopressin, has been found to shrink and produce ext ...
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Development of 95-gene classifi ...
Our aim was to develop an accurate diagnostic system using gene expression analysis by means of DNA microarray for prognosis of node-negative and es ...
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Breast cancer prognostic marker ...
Historically, new prognostic markers for breast cancer were assessed separately and sequentially in a series of studies, often with considerable cos ...
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Functional implication of TRAIL ...
Recently, TRAIL function has been elucidated beyond its known classical role of mediating cellular homeostasis and immune surveillance against trans ...
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Transient over-expression of es ...
Estrogen receptor-a (ERa) positive breast cancer frequently responds to inhibitors of ERa activity, such as tamoxifen, and/or to aromatase inhibitor ...
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Gene expression profile predict ...
Prognosis of early beast cancer is heterogeneous. Today, no histoclinical or biological factor predictive for clinical outcome after adjuvant anthra ...
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Stimulation of retinoic acid-in ...
The sodium iodide symporter (NIS) mediates the active iodide uptake in the thyroid gland as well as lactating breast tissue. Recently, we reported s ...
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Cytokeratin 5 positive cells re ...
A majority of breast cancers are estrogen receptor (ER) positive and have a luminal epithelial phenotype. However, these ER? tumors often contain h ...
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DEAD box 1: a novel and indepen ...
Breast cancer is a heterogeneous disease characterized by diverse molecular signatures and a variable response to therapy. Clinical management of br ...
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Uptake of 2-NBDG as a method to ...
This study quantifies uptake of a fluorescent glucose analog, (2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4- yl)amino)-2-deoxyglucose) (2-NBDG), in a large ...
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Identification of genes associa ...
Here we evaluated the cytotoxic effects of a combination of the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) and taxanes in ...
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Pachymic acid impairs breast ca ...
Pachymic acid (PA), a lanostane-type triterpenoid derived from Poria cocos, possesses demonstrated anti-inflammatory and anti-cancer activities. Non ...
605.95 KB
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Microcephalin is a new novel pr ...
The authors have investigated the expression of the microcephalin (MCPH1) protein to evaluate its prognostic importance in breast cancer. Microcepha ...
464.62 KB
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Time to move forward from ‘‘fir ...
For clinicians, it has been clear for many years that breast cancer patients with the same clinical and pathological characteristics can have divers ...
دانلود 1
120.18 KB
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Mutations and polymorphic BRCA ...
We previously showed that about 80% of breast cancer patients at high risk to carry mutation in BRCA genes presented at least one polymorphism in th ...
227.69 KB
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BRCA1 promoter methylation in p ...
BRCA1 promoter methylation reportedly plays an important part in the pathogenesis of human breast cancer. In the present study, we investigated whet ...
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Preclinical evaluation of nucle ...
Prevention and early detection of breast cancer are the major prophylactic measures taken to reduce the breast cancer related mortality and morbidit ...
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The management of ductal intrae ...
The management of ductal intraepithelial neoplasia (DIN) has substantially changed over the past 30 years, as its incidence has increased (from 2–3% ...
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Dual targeting of EphA2 and ER ...
Overexpression and altered function of EphA2 receptor tyrosine kinase are critical in the progression of breast cancer and provide a target for brea ...
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Decreased expression of EZH2 is ...
The purpose of this study is to investigate EZH2 in a large series of breast cancer patients for its prognostic and predictive value, and to evaluat ...
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