The association between IGF1 CA ...
Recently, we read with interest the article by Huang et al. [1]. They performed a meta-analysis of nine case–control studies (5,641 cases and 10,471 ...
Presence of MMTV-like env gene ...
Park et al. 2010 (No evidence of MMTV-like env sequences in specimens from the Australian Breast Cancer Family Study, Breast Cancer Research and Tre ...
Inhibition of aldehyde dehydrog ...
The majority of breast cancer deaths are because of ineffective treatment of metastatic disease. We previously identified a subpopulation of cells i ...
Mutation analysis of the SLX4/F ...
SLX4 coordinates three structure-specific endonucleases in the DNA damage response. One subtype of Fanconi anaemia, FA-P, has recently been attribut ...
Bone metastasis in a novel brea ...
In practice, investigations for bone metastasis of breast cancer rely heavily on models in vivo. Lacking of such ideal model makes it difficult to s ...
Unmet supportive care needs: a ...
The comparison of psychosocial needs across different cultural settings can identify cultural and service impacts on psychosocial outcomes. We compa ...
Insulin-like growth factor rece ...
Insulin-like growth factor-1 receptor (IGF-1R) is expressed in normal and malignant breast tissue and has been implicated in cell survival and resis ...
Estrogen and insulin-like growt ...
Although estrogen receptor alpha (ERa) and insulin-like growth factor (IGF) signaling are important for normal mammary development and breast cancer ...
Mutational characterization of ...
Understanding how cancer genes are mutated in individual tumors is an important issue with potential clinical and therapeutic impact. This is especi ...
Neoadjuvant chemotherapy in ER+ ...
A pathological complete remission (pCR) is rarely achieved by neoadjuvant chemotherapy in estrogen receptor-positive (ER?) HER2-negative (HER2-) tum ...
TP53 genomics predict higher cl ...
To determine rates of pathologic complete response (pCR) and near-complete response (npCR) in operable early-stage breast cancer using neoadjuvant ...
Oncological and cosmetic outcom ...
An inappropriate skin incision on the breast reduces the cosmetic benefit of breast-conserving surgery (BCS). To improve the cosmetic outcome, we ha ...
Combination of the proliferatio ...
Global gene expression profiles, consisting mainly of genes associated with proliferation, have been shown to subdivide histological grade 2 breast ...
Agonists and antagonists of GnR ...
Metastasis to bone is a frequent problem of advanced breast cancer. Particularly breast cancers, which do not express estrogen and progesterone rece ...
Post-lumpectomy intracavitary r ...
Liposomes are recognized drug delivery systems with tumor-targeting capability. In addition, therapeutic or diagnostic radionuclides can be efficien ...
Estrogen receptor b causes a G2 ...
The role of estrogen receptor beta (ERb) in breast cancer is unclear. ERb is considered to have a protective role in breast cancer development based ...
Characterization of BRCA1 and B ...
Mutations in BRCA1 and BRCA2 predispose carriers to early onset breast and ovarian cancer. A common problem in clinical genetic testing is interpret ...
Pathological complete response ...
Sequential doxorubicin/paclitaxel (AT) followed by CMF treatment was shown to be an active neoadjuvant chemotherapy regimen in the first European C ...
Sentinel lymph node biopsy comp ...
Sentinel lymph node biopsy (SLNB) has been recommended as the standard performance for negative sentinel lymph node (SLN) patients without axillary ...
Birth weight and other prenatal ...
Little is known about the role of birth weight and other prenatal factors in the etiology of breast cancer in Asian-Americans. We investigated the r ...
SerpinB3, a new prognostic tool ...
It is unclear which patients with breast cancer benefit from anthracycline-based neoadjuvant chemotherapy and whether taxanes increase survival. Hsp ...
Genomic analysis identifies uni ...
The ability to predict metastatic potential could be of great clinical importance, however, it is uncertain if predicting metastasis to specific vit ...
Outcome of triple-negative brea ...
More than 75% of breast cancers that develop in BRCA1 mutation carriers are triple-negative breast cancers (TNBC). The aim of this study was to comp ...
Targeted and intracellular trig ...
Limiting tumor invasion to the surrounding healthy tissues has proven to be clinically relevant for anticancer treatment options. We have demonstrat ...
Reproductive factors and histol ...
Evidence suggests that certain reproductive factors are more strongly associated with the incidence of lobular than of ductal breast cancer. The mec ...