Role of Allergen Sensitization in Older Adults
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Role of Allergen Sensitization ...
There is a common perception among physicians and patients that allergic diseases are not relevant in older adults. There is also recognition that i ...
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Basophils and Autoreactive IgE ...
Systemic lupus erythematosus (SLE) is a heterogeneous disease that can affect multiple organs. A hallmark of this disease, as is the case for other ...
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Importance of Allergy in Asthma ...
There has been a global epidemic of asthma during the past half-century. More recently, the prevalence has leveled off or declined in many Western c ...
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Severe Asthma with Fungal Sensi ...
A new phenotype of asthma has been described recently, namely severe asthma with fungal sensitization (SAFS). SAFS can be conceptualized as a contin ...
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Genetic Mechanisms Mediating At ...
Recent genome-wide association studies have demonstrated that common genetic variants in a region of chromosome 9p21 confer risk of coronary artery ...
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Prediction of Stroke Risk in At ...
Atrial fibrillation (AF) is a large public health problem that affects about 1% of the population in the United States. It confers an increased risk ...
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Evolving Concepts of the Role o ...
High-density lipoprotein (HDL) is classified as a negative risk factor due to the inverse relationship between elevated levels of HDL cholesterol an ...
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What Combination Therapy with a ...
The latest recommended goals for blood lipid levels may require multiple lipid drugs. Lower doses in combination may render more efficacy and safety ...
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MicroRNAs in Cardiometabolic Di ...
Defects in homeostatic regulation of cholesterol and fatty acids are associated with major cardiometabolic risk factors that are prevalent in type 2 ...
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Impact of Hypertension on Strok ...
Hypertension is the single most important risk factor for all types of stroke: ischemic stroke, intracerebral hemorrhage, and aneurysmal subarachnoi ...
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Diabetes and Cardiovascular Dis ...
The health burden of type 2 diabetes mellitus continues to increase worldwide. A substantial portion of this burden is due to the development of car ...
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Atherosclerosis: An Epigenetic ...
Increasing evidence points to dietary lipids and their derivates as dynamic modulators of pro- or anti-inflammatory gene expression pathways via the ...
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Statin Rebound or Withdrawal Sy ...
Studies in vascular cells in culture and in laboratory animals revealed that statin discontinuation triggers a rebound deterioration of vascular fun ...
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Blood Lipids and Stroke: What M ...
Statin therapy has became the most important advance in stroke prevention since the introduction of aspirin and blood pressure–lowering therapies. O ...
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Vasculotoxic Effects of Insulin ...
As a result of ambiguous results from several recent trials in diabetes, scrutiny has focused on the potential effects of insulin and its role in at ...
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Genetics of Redox Systems and T ...
As atherosclerosis is still one of the major causes of death in Western populations, it is important to identify those individuals who are at increa ...
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Antithrombotic Management for T ...
The new definition and risk stratification for transient ischemic attack (TIA) have clear implications for the urgency of evaluation and treatment. ...
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Statin Therapy in Metabolic Syn ...
Much evidence supports a pivotal role for inflammation in atherosclerosis. C-reactive protein (CRP), the prototypic marker of inflammation in humans ...
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The Role of Anxiety and Emotion ...
Depression and anxiety are both known to be comorbid with coronary heart disease. Given the high prevalence of coronary heart disease today, specifi ...
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Genome-Wide Association Studies ...
Cardiovascular disease remains the major cause of worldwide morbidity and mortality. Its pathophysiology is complex and multifactorial. Because the ...
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Current Management of Symptomat ...
Intracranial arterial stenosis (IAS) is the cause of about 10% of all ischemic strokes in the United States, but may account for about 40% of stroke ...
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The Anti-Ischemic and Anti-Angi ...
Angina pectoris resulting from myocardial ischemia afflicts half of all patients with coronary heart disease (CHD). Chronic angina remains a major p ...
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The Role of Lipoprotein-Associa ...
Lipoprotein-associated phospholipase A2 (Lp- PLA2) is an enzyme that generates inflammatory mediators within atherosclerotic plaques. In epidemiolog ...
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Update on HDL Receptors and Cel ...
Efflux is central to maintenance of tissue and whole body cholesterol homeostasis. The discovery of cell surface receptors that bind high-density li ...
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Prevention of Stroke Following ...
Transient ischemic attacks (TIAs) are common neurologic events characterized by stroke-like symptoms that completely resolve. They were previously t ...
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