Expanding the Role of Neuromodulation for Overactive Bl ...
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Augmentation Cystoplasty
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Expanding the Role of Neuromodu ...
From the time that it was granted US Food and Drug Administration approval, neuromodulation has secured a firm position in the treatment algorithm f ...
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Bladder Augmentation and the Ri ...
Augmentation cystoplasty is the gold standard for increasing bladder capacity and improving bladder compliance in patients with refractory neurogeni ...
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Augmentation Cystoplasty
Although more conservative measures are used as first-line treatment of patients with overactive bladder and for those with small capacity, low-comp ...
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Purinoceptors and Bladder Dysfu ...
Purinergic signaling is increasingly appreciated as an important contributor to the normal bladder functions of urine storage and voiding. The trans ...
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Treatment of Neurogenic Voiding ...
The neurophysiology of volitional voiding is a poorly understood and constantly evolving field. Some of the most difficult clinical problems in urol ...
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New Insights into the Pathophys ...
Detrusor-sphincter dyssynergia (DSD) is a condition in which the urethral outlet actively contracts during a detrusor contraction. This is most ofte ...
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Bladder Neck Dysfunction in Spi ...
Spinal cord injury (SCI) impairs the voluntary and autonomic control of storage and emptying functions of the urinary bladder, leading to a marked r ...
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Future Directions in Overactive ...
Overactive bladder (OAB) remains a remarkably common urologic condition resulting in significant clinical and economic sequelae. Although likely und ...
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Pharmacodynamics of Overactive ...
Understanding the role of pharmacodynamics in determining a drug’s effect helps prescribing physicians choose the most appropriate agent and regimen ...
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Metabolic Syndrome and Breast C ...
Obesity is one of the most important known preventable causes of cancer, accounting for up to 20% of cancer deaths in women. Obese women have increa ...
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Insulin-Like Growth Factor Path ...
The insulin-like growth factor (IGF) pathway plays an important role in cancer development, survival, metastasis, and resistance to antineoplastic t ...
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Patient Selection and Technical ...
Skin-sparing (SSM) and nipple-sparing mastectomy (NSM) have gained widespread popularity over the past few years. Breast reconstruction is facilitat ...
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Hedgehog Pathway Inhibitors: Po ...
The Hedgehog (Hh) signaling pathway is a developmental pathway with important roles in embryogenesis, epithelial-mesenchymal transition, stem/progen ...
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Breast Preservation in Patients ...
Mastectomy is the current standard of care following in-breast local recurrence of breast cancer previously treated with breast-conserving surgery a ...
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Management of Aromatase Inhibit ...
With increased use of aromatase inhibitors (AIs) in the adjuvant and first-line metastatic settings for postmenopausal women with estrogen receptor ...
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Sentinel Lymph Node Biopsy Afte ...
The timing of sentinel lymph node (SLN) biopsy in patients receiving neoadjuvant chemotherapy remains a debated topic, despite increasing literature ...
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How Can the AJCC Staging System ...
Although the current American Joint Commission on Cancer (AJCC) staging system is the most widely used classification scheme for the prognostication ...
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Cryoablation as a Replacement f ...
With improvements in technology, freezing malignant tissue (cryoablation) as an alternative to surgery has been used to treat cancers of the skin, p ...
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Reoperative Sentinel Lymph Node ...
The role of sentinel lymph node biopsy for staging of primary breast cancer is well established. However, in cases of previous surgery to the breast ...
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Who Benefits from Nodal Field I ...
Randomized clinical trials and meta-analyses have clearly demonstrated that radiation after definitive surgery can improve local-regional control an ...
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Percutaneous Mitral Repair: Pat ...
Percutaneous heart valve therapies are rapidly changing our approach to valvular heart diseases. Currently, mitral valve surgery is the treatment of ...
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Risk Scores for Predicting Outc ...
Risk scoring tools have been developed from clinical databases to predict expected patient mortality from cardiac surgical procedures. The risk algo ...
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Heart Failure Pharmacogenetics: ...
Heart failure is an increasingly common disease associated with significant morbidity and mortality in the aging population. Recent advances in hear ...
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Role of Coronary Artery Calcium ...
Coronary heart disease is the leading cause of death worldwide, and has traditionally been assessed through a patient’s cardiovascular risk profile ...
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Stroke Prevention in the High-r ...
Medical management of patients with atrial fibrillation (AF) at high risk for stroke is limited by problems of imperfect tools for assessment of thr ...
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