Commentary: Implications of Can ...
In an increasing number of settings it is appropriate to consider cancer as a very serious but also a chronic disease process. This commentary discu ...
Curable Metastatic Colorectal C ...
In the United States and Europe, colorectal cancer (CRC) is the third most common malignancy and the second leading cause of cancer-related death fo ...
Abiraterone Acetate, A Novel Ad ...
The androgen receptor remains the key player in patients with castration-resistant prostate cancer (CRPC). Available agents capable of blocking earl ...
Update on Treatment Advances in ...
Concurrent radiation therapy and chemotherapy is the primary treatment for patients with squamous cell tumors of the anal canal, and is also employe ...
The Need to Examine Metastatic ...
Knowledge of estrogen receptor (ER), progesterone receptor (PgR) and human epidermal growth factor receptor-2 (HER2) status is necessary for determi ...
Malignant Pleural Mesothelioma
Malignant pleural mesothelioma (MPM) is a relatively rare thoracic malignancy accounting for about 2000–3000 new cases per year. This cancer has bee ...
Ramucirumab (IMC-1121B): Monocl ...
Angiogenesis, a well-recognized characteristic of malignancy, has been exploited more than any other pathway targeted by biologic anti-neoplastic th ...
Development of Second-Generatio ...
The vascular endothelial growth factor (VEGF) signaling pathway appears to be the dominant pathway involved in tumor angiogenesis, providing a ratio ...
Hepatocellular Carcinoma: Preve ...
Hepatocellular carcinoma (HCC) is an aggressive malignancy of the liver and occurs most often in the setting of chronic liver disease. The most comm ...
Medical Treatment of Mesothelio ...
In the present report, we review the current standard and investigational treatments of malignant pleural mesothelioma (MPM). Several studies have r ...
Tumor Profiling: Development of ...
Primary brain tumors are a heterogeneous group of malignancies with highly variable outcomes, and diagnosis is largely based on the histological app ...
Sipuleucel-T: Prototype for Dev ...
Prostate cancer immunotherapy officially debuted with the recent FDA approval of Sipuleucel-T. The novel trend of cancer immunotherapy relies on the ...
Current Treatment Options for P ...
Pancreas cancer is a significant cause of cancer mortality; therefore, the development of early diagnostic strategies and effective treatment is ess ...
The Optimal Chemotherapy for St ...
Nearly one third of non–small cell lung cancer (NSCLC) patients at diagnosis have stage III disease. Concurrent chemoradiation has emerged as the st ...
Patient Profiling for Treatment ...
Significant advances have been made in the identification of genes associated with the occurrence and prognosis of a variety of cancers. Recent effo ...
Quality of Care in Head and Nec ...
Improving the quality of health care has become a national priority, as indicated by the establishment of multiple federal initiatives and by the ac ...
Predictive and Prognostic Marke ...
Colorectal cancer (CRC) has a complex pathogenesis involving multiple sequential steps with accumulation of genetic alterations including mutations, ...
The Evolving Role of Targeted T ...
Many of the leading developments in management of non-small cell lung cancer (NSCLC) have been provided by the integration of specific targeted ther ...
Incorporation of Biomarker Asse ...
Advances in molecular genetics have aided the identification of potential biomarkers with significant clinical promise in neurooncology. These advan ...
Changing the Perspective: Curre ...
Functional outcome and quality of life have become frequent outcome measures in head and neck cancer (HNC) clinical trials. Many thoroughly validate ...
Variant Forms of Bladder Cancer ...
Variant forms of bladder cancer are non-urothelial neoplasms or urothelial carcinomas mixed with other histologies. Compared to pure urothelial carc ...
Palliative Medicine: Barriers a ...
The development of palliative care in China is vital to the care of its aging population and associated increase in cancer incidence. There are phys ...
Response Assessment in Neuro-On ...
Accuracy and reproducibility in determining response to therapy and tumor progression can be difficult to achieve for nervous system tumors. Current ...
Second Primary Tumors in Patien ...
This is a review on second primary tumors in patients with head and neck cancer. These patients have a high risk of developing other cancers simulta ...